Standard name Systematic name Name description Description
FAR1 YJL157C CDK inhibitor and nuclear anchor CDK inhibitor and nuclear anchor; during the cell cycle Far1p sequesters the GEF Cdc24p in the nucleus; phosphorylation by Cdc28p-Cln results in SCFCdc4 complex-mediated ubiquitin-dependent degradation, releasing Cdc24p for export and activation of GTPase Cdc42p; in response to pheromone, phosphorylation of Far1p by MAPK Fus3p results in association with, and inhibition of Cdc28p-Cln, as well as Msn5p mediated nuclear export of Far1p-Cdc24p, targeting Cdc24p to polarity sites
Visualize the interactome of FAR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2/M 136

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.703 0.816 0.894
Mito 0.059 NaN NaN
Nucleus 0.183 0.112 0.064
Vac/Vac Memb 0.127 0.095 0.064

GFP localization & abundance

GFP localization GFP abundance
nucleus 238

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FAR1 0 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 14 5 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 9 4 7 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid
BEM1 YBR200W Protein containing SH3-domains physical 9 3 5 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle physical 7 3 6 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 5 3 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Co-crystal Structure
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 4 3 4 Phenotypic Enhancement, Synthetic Lethality, Synthetic Rescue, Phenotypic Enhancement
STE4 YOR212W G protein beta subunit physical 4 3 3 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions physical 4 3 3 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 3 2 3 Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 3 2 3 Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 3 3 2 Dosage Rescue, Phenotypic Suppression, Phenotypic Enhancement
MCM1 YMR043W Transcription factor genetic 3 3 1 Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression
MSN5 YDR335W Karyopherin physical 3 2 1 Affinity Capture-Western, Two-hybrid, Two-hybrid
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
CLN3 YAL040C G1 cyclin involved in cell cycle progression physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
PKC1 YBL105C Protein serine/threonine kinase regulation 2 2 1 physical interaction evidence, protein kinase assay evidence
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CDC42 YLR229C Small rho-like GTPase physical 1 1 1 Two-hybrid
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Phenotypic Suppression
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Synthetic Rescue
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
GSP1 YLR293C Ran GTPase physical 1 1 1 Affinity Capture-Western
STE18 YJR086W G protein gamma subunit physical 1 1 1 Affinity Capture-Western
STE4 YOR212W G protein beta subunit genetic 1 1 1 Phenotypic Suppression
LSM2 YBL026W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-RNA
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
UFO1 YML088W F-box receptor protein physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Synthetic Lethality
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Phenotypic Enhancement
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 1 1 1 Phenotypic Suppression
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Phenotypic Suppression
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Phenotypic Suppression
STE7 YDL159W Signal transducing MAP kinase kinase genetic 1 1 1 Phenotypic Suppression
GPA1 YHR005C Subunit of G protein involved in pheromone response genetic 1 1 1 Phenotypic Suppression
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Phenotypic Enhancement
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Phenotypic Suppression
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Synthetic Growth Defect
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-Western
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Phenotypic Enhancement
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase physical 1 1 1 Affinity Capture-MS