FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
genetic |
9 |
6 |
7 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Lethality, Dosage Rescue, Negative Genetic, Negative Genetic, Synthetic Rescue |
FTR1 |
YER145C |
High affinity iron permease |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Rescue |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Growth Defect |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
northern blot evidence |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP13 |
YLR222C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBL036C |
YBL036C |
Putative non-specific single-domain racemase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAG2 |
YLR427W |
Cytoplasmic protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Co-fractionation |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FET5 |
YFL041W |
Multicopper oxidase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMA111 |
YNL123W |
Serine protease and general molecular chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL33 |
YBR297W |
MAL-activator protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI5 |
YLR204W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL036W |
YOL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCS2 |
YOR173W |
m(7)GpppX pyrophosphatase regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |