| MSS11 |
YMR164C |
Transcription factor |
regulation |
4 |
4 |
4 |
beta-galactosidase reporter gene assay evidence, DNA to cDNA expression microarray evidence, northern blot evidence, nucleic acid binding evidence |
| FLO8 |
YER109C |
Transcription factor |
regulation |
3 |
3 |
3 |
beta-galactosidase reporter gene assay evidence, northern blot evidence, nucleic acid binding evidence |
| UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
2 |
2 |
2 |
DNA to cDNA expression microarray evidence, quantitative reverse transcription polymerase chain reaction evidence |
| TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
regulation |
2 |
2 |
2 |
DNA to cDNA expression microarray evidence, northern blot evidence |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
| YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YLR287C |
YLR287C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
| ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Phenotypic Suppression |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
regulation |
1 |
1 |
1 |
northern blot evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
regulation |
1 |
1 |
1 |
northern blot evidence |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
northern blot evidence |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
regulation |
1 |
1 |
1 |
nucleic acid binding evidence |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
regulation |
1 |
1 |
1 |
nucleic acid binding evidence |
| RGT1 |
YKL038W |
Glucose-responsive transcription factor |
regulation |
1 |
1 |
1 |
northern blot evidence |
| ASG1 |
YIL130W |
Zinc cluster protein proposed to be a transcriptional regulator |
regulation |
1 |
1 |
1 |
northern blot evidence |
| MFG1 |
YDL233W |
Regulator of filamentous growth |
regulation |
1 |
1 |
1 |
nucleic acid binding evidence |
| MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
regulation |
1 |
1 |
1 |
northern blot evidence |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
regulation |
1 |
1 |
1 |
northern blot evidence |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA4 |
YHR011W |
Probable mitochondrial seryl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ARP10 |
YDR106W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BPL1 |
YDL141W |
Biotin:apoprotein ligase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| COQ11 |
YLR290C |
Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| IRA1 |
YBR140C |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| FLO8 |
YER109C |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| YDR415C |
YDR415C |
Putative aminopeptidase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MSS11 |
YMR164C |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR071C |
YNR071C |
Putative aldose 1-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFG1 |
YOR315W |
Nuclear protein putative transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| DIA1 |
YMR316W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ASP3-4 |
YLR160C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DIA3 |
YDL024C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CSS3 |
YOL159C |
Protein of unknown function, secreted when constitutively expressed |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALP1 |
YNL270C |
Arginine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO10 |
YKR102W |
Member of the FLO family of cell wall flocculation proteins |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |