| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
13 |
5 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, PCA, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
| GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
12 |
4 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
physical |
11 |
3 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
6 |
3 |
6 |
Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Dosage Rescue, Dosage Rescue |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
6 |
4 |
4 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic, Negative Genetic |
| GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
6 |
3 |
4 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Rescue |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
physical |
4 |
2 |
4 |
Two-hybrid, Two-hybrid, Two-hybrid, Co-localization |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Negative Genetic, Negative Genetic |
| CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| CWC21 |
YDR482C |
Protein involved in RNA splicing by the spliceosome |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APL3 |
YBL037W |
Alpha-adaptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUT1 |
YHL032C |
Glycerol kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IST1 |
YNL265C |
Protein with positive role in the multivesicular body sorting pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HXT7 |
YDR342C |
High-affinity glucose transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLC1 |
YDL052C |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCX1 |
YBR227C |
Non-proteolytic ATPase of the AAA family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GUF1 |
YLR289W |
Mitochondrial matrix GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
| TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| LSM5 |
YER146W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YER079W |
YER079W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM7 |
YJR113C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP1 |
YMR204C |
Peripheral membrane protein of peroxisomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPS16 |
YPL013C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR363W-A |
YLR363W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAP1 |
YHR047C |
Arginine/alanine amino peptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBP6 |
YBR120C |
Mitochondrial protein required for translation of the COB mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTR1 |
YPR124W |
High-affinity copper transporter of plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC19 |
YAL038W |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Positive Genetic |