Standard name Systematic name Name description Description
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine Plasma membrane transporter for choline, ethanolamine, and carnitine; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
Visualize the interactome of HNM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.879 0.917 0.893
Cort. Patches 0.171 0.198 0.154
Cytoplasm 0.070 0.104 NaN
ER 0.050 NaN 0.050

GFP localization & abundance

GFP localization GFP abundance
cell periphery, bud technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HNM1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1149 (ethanolamine transport), r_1684 (choline transport), r_1125 (choline transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily physical 2 1 2 PCA, PCA
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 2 1 1 Positive Genetic, Positive Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 1 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
OPI1 YHL020C Transcriptional regulator of a variety of genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Positive Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Positive Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic physical 1 1 1 PCA
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Phenotypic Enhancement
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Dosage Growth Defect
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 PCA
ECM10 YEL030W Heat shock protein of the Hsp70 family genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) physical 1 1 1 PCA
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Negative Genetic
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Positive Genetic
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
RFS1 YBR052C Protein of unknown function physical 1 1 1 PCA
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 PCA
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 1 1 1 PCA
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 PCA
TVP15 YDR100W Integral membrane protein physical 1 1 1 PCA
ITR1 YDR497C Myo-inositol transporter physical 1 1 1 PCA
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain physical 1 1 1 PCA
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 PCA
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
WSC3 YOL105C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 PCA
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 PCA
MEP3 YPR138C Ammonium permease of high capacity and low affinity physical 1 1 1 PCA
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
RBD2 YPL246C Possible rhomboid protease physical 1 1 1 PCA
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 PCA
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
YVH1 YIR026C Dual specificity protein phosphatase physical 1 1 1 PCA
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
YJU3 YKL094W Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters physical 1 1 1 PCA
MEP1 YGR121C Ammonium permease physical 1 1 1 PCA
MSC3 YLR219W Protein of unknown function physical 1 1 1 PCA
YLR326W YLR326W Putative protein of unknown function physical 1 1 1 PCA
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 PCA
LSP1 YPL004C Eisosome core component physical 1 1 1 PCA
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 PCA
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 PCA
HXT5 YHR096C Hexose transporter with moderate affinity for glucose physical 1 1 1 PCA
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 PCA
YGL108C YGL108C Protein of unknown function, predicted to be palmitoylated physical 1 1 1 PCA
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
INA1 YLR413W Protein of unknown function physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 PCA
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 PCA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Reconstituted Complex
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 PCA
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) genetic 1 1 1 Positive Genetic
POS5 YPL188W Mitochondrial NADH kinase genetic 1 1 1 Positive Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
PHO8 YDR481C Repressible vacuolar alkaline phosphatase genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Dosage Rescue
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
MRPS12 YNR036C Mitochondrial protein genetic 1 1 1 Negative Genetic
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Negative Genetic
RAX1 YOR301W Protein involved in establishing bud site selection genetic 1 1 1 Negative Genetic
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Positive Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI physical 1 1 1 PCA
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Synthetic Growth Defect
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease physical 1 1 1 PCA
ANY1 YMR010W Protein involved in phospholipid flippase function physical 1 1 1 PCA
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
FLC1 YPL221W Flavin adenine dinucleotide transporter physical 1 1 1 PCA
DUR3 YHL016C Plasma membrane transporter for both urea and polyamines physical 1 1 1 PCA
CHO1 YER026C Phosphatidylserine synthase genetic 1 1 1 Synthetic Lethality
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic