Standard name Systematic name Name description Description
NPL6 YMR091C Component of the RSC chromatin remodeling complex Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions
Visualize the interactome of NPL6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.436 0.413 0.292
Nucleus 0.846 0.822 0.877

GFP localization & abundance

GFP localization GFP abundance
nucleus 3510

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NPL6 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 12 3 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 9 2 6 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 7 1 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 7 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RSC58 YLR033W Component of the RSC chromatin remodeling complex physical 7 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 6 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RSC4 YKR008W Component of the RSC chromatin remodeling complex physical 6 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 6 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC9 YML127W Component of the RSC chromatin remodeling complex physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC1 YGR056W Component of the RSC chromatin remodeling complex physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
RSC30 YHR056C Component of the RSC chromatin remodeling complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
HHF1 YBR009C Histone H4 physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
REB1 YBR049C RNA polymerase I enhancer binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
RSC3 YDR303C Component of the RSC chromatin remodeling complex genetic 2 2 1 Synthetic Lethality, Dosage Rescue
RAD51 YER095W Strand exchange protein genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 1 1 1 Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Dosage Rescue
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
RSC30 YHR056C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Synthetic Growth Defect
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Synthetic Growth Defect
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Growth Defect
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Synthetic Growth Defect
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Growth Defect
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Synthetic Growth Defect
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Synthetic Growth Defect
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Synthetic Growth Defect
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Growth Defect
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Rescue
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Affinity Capture-MS
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Synthetic Growth Defect
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Synthetic Growth Defect
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Reconstituted Complex
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Synthetic Growth Defect
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Synthetic Growth Defect
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Growth Defect
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Growth Defect
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HHT2 YNL031C Histone H3 physical 1 1 1 Reconstituted Complex
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 1 1 1 Synthetic Growth Defect
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit physical 1 1 1 Affinity Capture-MS
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex physical 1 1 1 Affinity Capture-MS
FRD1 YEL047C Soluble fumarate reductase physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Synthetic Growth Defect
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Synthetic Growth Defect
MSC1 YML128C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect