Standard name Systematic name Name description Description
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; is ubiquitinated by Dma1p; phosphorylation by Pho85p targets it for degradation; localizes to sites of polarized cell growth
Visualize the interactome of PCL1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 54

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 606

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PCL1 1 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PHO85 YPL031C Cyclin-dependent kinase physical 7 5 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex
BNI1 YNL271C Formin genetic 4 4 4 Synthetic Lethality, Phenotypic Enhancement, Dosage Lethality, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
SLT2 YHR030C Serine/threonine MAP kinase genetic 4 3 4 Dosage Rescue, Synthetic Growth Defect, Dosage Growth Defect, Dosage Rescue
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 4 4 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
NCP1 YHR042W NADP-cytochrome P450 reductase physical 4 4 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors physical 4 4 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor regulation 3 3 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 3 2 3 Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality
DMA1 YHR115C Ubiquitin-protein ligase (E3) physical 3 2 2 Biochemical Activity, Affinity Capture-Western, Biochemical Activity
MSN2 YMR037C Stress-responsive transcriptional activator regulation 2 2 2 chromatin immunoprecipitation-chip evidence, RNA-sequencing evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Phenotypic Enhancement, Synthetic Lethality
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Synthetic Lethality, Dosage Rescue
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 2 1 2 Negative Genetic, Negative Genetic
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
SWI6 YLR182W Transcription cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 2 1 2 Negative Genetic, Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 2 1 2 Negative Genetic, Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 2 1 2 Negative Genetic, Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 2 1 2 Negative Genetic, Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 2 1 2 Negative Genetic, Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 2 1 2 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 2 1 Two-hybrid, Affinity Capture-Western
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AFT2 YPL202C Iron-regulated transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MCM1 YMR043W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PUT3 YKL015W Transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis regulation 1 1 1 DNA to cDNA expression microarray evidence
RDR1 YOR380W Transcriptional repressor involved in regulating multidrug resistance regulation 1 1 1 DNA to cDNA expression microarray evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Biochemical Activity
NPL3 YDR432W RNA-binding protein physical 1 1 1 Biochemical Activity
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Phenotypic Enhancement
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Biochemical Activity
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Dosage Rescue
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions physical 1 1 1 Affinity Capture-Western
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Dosage Rescue
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase physical 1 1 1 Affinity Capture-Western
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Dosage Lethality
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Dosage Lethality
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-Western
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 1 1 1 Biochemical Activity
SHS1 YDL225W Component of the septin ring that is required for cytokinesis physical 1 1 1 Biochemical Activity
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Biochemical Activity
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Biochemical Activity
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Biochemical Activity
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Biochemical Activity
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Biochemical Activity
SSD1 YDR293C Translational repressor physical 1 1 1 Biochemical Activity
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Biochemical Activity
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Dosage Rescue
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Dosage Rescue
YKE4 YIL023C Zinc transporter genetic 1 1 1 Dosage Rescue
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Dosage Lethality
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Dosage Growth Defect
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Synthetic Growth Defect
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
VHS2 YIL135C Regulator of septin dynamics genetic 1 1 1 Dosage Rescue
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Dosage Lethality
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Dosage Rescue
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Phenotypic Enhancement
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation physical 1 1 1 Biochemical Activity
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Biochemical Activity
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex physical 1 1 1 Biochemical Activity
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Dosage Rescue
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Dosage Rescue
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Biochemical Activity
ISR1 YPR106W Predicted protein kinase physical 1 1 1 Biochemical Activity
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity physical 1 1 1 Biochemical Activity
MLF3 YNL074C Serine-rich protein of unknown function genetic 1 1 1 Dosage Rescue
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic