Standard name Systematic name Name description Description
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) Mitochondrial type 2C protein phosphatase (PP2C); involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; localizes to the intermembrane space and is imported via the presequence pathway and processed by the inner membrane protease (Imp1p-Imp2p); acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p
Visualize the interactome of PTC5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 7550

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PTC5 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 2 1 2 Negative Genetic, Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Dosage Growth Defect
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Dosage Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
NUC1 YJL208C Major mitochondrial nuclease physical 1 1 1 Affinity Capture-MS
NOC2 YOR206W Protein involved in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
FMP52 YER004W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Co-fractionation
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
RCF2 YNR018W Cytochrome c oxidase subunit physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SCO2 YBR024W Protein anchored to mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
SCW4 YGR279C Cell wall protein with similarity to glucanases physical 1 1 1 Affinity Capture-MS
SIP5 YMR140W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
TIM10 YHR005C-A Essential protein of the mitochondrial intermembrane space physical 1 1 1 Affinity Capture-MS
TIM50 YPL063W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
TIM54 YJL054W Component of the mitochondrial TIM22 complex physical 1 1 1 Affinity Capture-MS
TOM40 YMR203W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Affinity Capture-MS
TRR1 YDR353W Cytoplasmic thioredoxin reductase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
YDL124W YDL124W NADPH-dependent alpha-keto amide reductase physical 1 1 1 Affinity Capture-MS
YME1 YPR024W Catalytic subunit of i-AAA protease complex physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Dosage Growth Defect
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
PGM2 YMR105C Phosphoglucomutase physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Positive Genetic
DSS1 YMR287C 3'-5' exoribonuclease genetic 1 1 1 Positive Genetic
MOH1 YBL049W Protein of unknown function, essential for stationary phase survival physical 1 1 1 Affinity Capture-MS
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Positive Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Positive Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane physical 1 1 1 Affinity Capture-MS
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
CDD1 YLR245C Cytidine deaminase physical 1 1 1 Affinity Capture-MS
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
HNT1 YDL125C Adenosine 5'-monophosphoramidase physical 1 1 1 Affinity Capture-MS
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p physical 1 1 1 Affinity Capture-MS
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p physical 1 1 1 Affinity Capture-MS
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase physical 1 1 1 Affinity Capture-MS
ERG5 YMR015C C-22 sterol desaturase physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
ETR1 YBR026C 2-enoyl thioester reductase physical 1 1 1 Affinity Capture-MS
NDE2 YDL085W Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex physical 1 1 1 Affinity Capture-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Affinity Capture-MS
CYT1 YOR065W Cytochrome c1 physical 1 1 1 Affinity Capture-MS
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
COX11 YPL132W Protein required for delivery of copper to Cox1p physical 1 1 1 Affinity Capture-MS
CYC2 YOR037W Mitochondrial peripheral inner membrane protein physical 1 1 1 Affinity Capture-MS
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p physical 1 1 1 Affinity Capture-MS
FMP25 YLR077W Protein required for assembly of respiratory complex III physical 1 1 1 Affinity Capture-MS
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology physical 1 1 1 Affinity Capture-MS
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function physical 1 1 1 Affinity Capture-MS
PIG2 YIL045W Putative type-1 protein phosphatase targeting subunit physical 1 1 1 Affinity Capture-MS
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS