Standard name Systematic name Name description Description
RAD2 YGR258C Single-stranded DNA endonuclease Single-stranded DNA endonuclease; cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein
Visualize the interactome of RAD2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.178 0.390 0.573
Nucleus 0.836 0.683 0.698
Vac/Vac Memb 0.121 0.195 NaN
Cytoplasm NaN 0.122 0.073

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 846

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RAD2 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 5 3 4 Reconstituted Complex, Co-purification, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
SRB4 YER022W Subunit of the RNA polymerase II mediator complex physical 5 3 2 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Two-hybrid
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 4 2 3 Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid
RAD18 YCR066W E3 ubiquitin ligase genetic 3 3 3 Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 3 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
APN1 YKL114C Major apurinic/apyrimidinic endonuclease genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
SSL2 YIL143C Component of RNA polymerase transcription factor TFIIH holoenzyme physical 2 2 2 Reconstituted Complex, Co-purification
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
MSH2 YOL090W Protein that binds to DNA mismatches physical 2 2 1 Affinity Capture-Western, Two-hybrid
TPM1 YNL079C Major isoform of tropomyosin genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
NUT1 YGL151W Component of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-Western
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Phenotypic Enhancement
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Phenotypic Suppression
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Synthetic Growth Defect
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Synthetic Growth Defect
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Positive Genetic
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Synthetic Rescue
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Phenotypic Enhancement
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Synthetic Lethality
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 1 1 1 Affinity Capture-Western
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 1 1 1 PCA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
RAD3 YER171W 5' to 3' DNA helicase physical 1 1 1 Co-purification
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH physical 1 1 1 Co-purification
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease physical 1 1 1 Affinity Capture-MS
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Phenotypic Enhancement
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Phenotypic Enhancement
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Dosage Rescue
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Phenotypic Enhancement
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Rescue
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Phenotypic Suppression
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Phenotypic Suppression
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Phenotypic Suppression
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Synthetic Rescue
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
MAP1 YLR244C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
HIM1 YDR317W Protein of unknown function involved in DNA repair genetic 1 1 1 Phenotypic Enhancement