Standard name Systematic name Name description Description
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA Essential serine kinase involved in the processing of 20S pre-rRNA; involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p
Visualize the interactome of RIO2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.984 0.989 0.982

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 10300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RIO2 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 20 6 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-fractionation
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 19 6 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 17 5 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
LTV1 YKL143W Subunit of the EGO/GSE complex physical 16 5 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Co-crystal Structure, Co-fractionation, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 15 6 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 14 6 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 10 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 9 4 9 Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 9 4 8 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 8 3 8 Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 6 3 6 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 5 3 5 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS8B YER102W Protein component of the small (40S) ribosomal subunit physical 3 2 3 Co-fractionation, Affinity Capture-MS, Affinity Capture-MS
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing physical 3 2 2 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing genetic 2 2 2 Synthetic Lethality, Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YGR054W YGR054W Eukaryotic initiation factor eIF2A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS18B YML026C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 1 2 Negative Genetic, Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
RAX2 YLR084C Protein required for the maintenance of bud site selection genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Positive Genetic
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
AVO1 YOL078W Component of the membrane-bound TORC2 complex physical 1 1 1 Affinity Capture-MS
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs genetic 1 1 1 Negative Genetic
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 1 1 1 Affinity Capture-MS
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
DUR12 YBR208C Urea amidolyase genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Affinity Capture-MS
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
TSR2 YLR435W Protein with a potential role in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
RRP15 YPR143W Nucleolar protein physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 1 1 1 Affinity Capture-MS
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 Co-crystal Structure
TIF11 YMR260C Translation initiation factor eIF1A physical 1 1 1 Co-crystal Structure
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Co-crystal Structure
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS23B YPR132W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
YRB2 YIL063C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Positive Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Negative Genetic
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Negative Genetic
VPS73 YGL104C Mitochondrial protein genetic 1 1 1 Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
VHR1 YIL056W Transcriptional activator genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
YKL050C YKL050C Protein of unknown function genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Negative Genetic
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Negative Genetic
YPL034W YPL034W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Affinity Capture-MS
GSP1 YLR293C Ran GTPase physical 1 1 1 Reconstituted Complex
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Positive Genetic
PXR1 YGR280C Essential protein involved in rRNA and snoRNA maturation physical 1 1 1 Affinity Capture-MS
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Positive Genetic
NOP13 YNL175C Nucleolar protein found in preribosomal complexes genetic 1 1 1 Negative Genetic
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
APE2 YKL157W Aminopeptidase yscII genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Positive Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase physical 1 1 1 Affinity Capture-MS
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
CTL1 YMR180C RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm genetic 1 1 1 Negative Genetic
BNA6 YFR047C Quinolinate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins physical 1 1 1 Affinity Capture-MS
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-Western
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 1 1 1 Affinity Capture-Western
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Synthetic Lethality
MTR2 YKL186C mRNA transport regulator physical 1 1 1 Affinity Capture-Western
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Synthetic Lethality
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
GAP1 YKR039W General amino acid permease genetic 1 1 1 Positive Genetic
NNK1 YKL171W Protein kinase genetic 1 1 1 Negative Genetic
PEX27 YOR193W Peripheral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Co-fractionation
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Affinity Capture-MS
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Positive Genetic
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Positive Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Positive Genetic
IGO2 YHR132W-A Protein required for initiation of G0 program genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Positive Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
PUT1 YLR142W Proline oxidase genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
IZH1 YDR492W Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic