| SLA1 | YBL007C | Cytoskeletal protein binding protein | physical | 4 | 2 | 4 | Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid | 
            
                | RVS167 | YDR388W | Calmodulin-binding actin-associated protein | physical | 4 | 2 | 4 | Two-hybrid, Protein-peptide, Two-hybrid, Two-hybrid | 
            
                | LSB3 | YFR024C-A | Protein containing a C-terminal SH3 domain | physical | 4 | 2 | 4 | Protein-peptide, Two-hybrid, Two-hybrid, Two-hybrid | 
            
                | YSC84 | YHR016C | Actin-binding protein | physical | 3 | 2 | 3 | Protein-peptide, Two-hybrid, Two-hybrid | 
            
                | IQG1 | YPL242C | Actin filament binding protein that enhances actin ring formation | genetic | 3 | 3 | 2 | Dosage Rescue, Synthetic Growth Defect, Negative Genetic | 
            
                | INP53 | YOR109W | Polyphosphatidylinositol phosphatase | physical | 3 | 2 | 2 | Affinity Capture-Western, Two-hybrid, Affinity Capture-Western | 
            
                | CYK3 | YDL117W | SH3-domain protein located in the bud neck and cytokinetic actin ring | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | UBP3 | YER151C | Ubiquitin-specific protease that cleaves Ub-protein fusions | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | FAR7 | YFR008W | Protein involved in recovery from pheromone-induced cell cycle arrest | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | QCR9 | YGR183C | Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | YHR140W | YHR140W | Endoplasmic reticulum protein | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | BRE2 | YLR015W | Subunit of COMPASS (Set1C) complex | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | RVS161 | YCR009C | Amphiphysin-like lipid raft protein | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | SNF4 | YGL115W | Activating gamma subunit of the AMP-activated Snf1p kinase complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | RRD1 | YIL153W | Peptidyl-prolyl cis/trans-isomerase | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | SNX4 | YJL036W | Sorting nexin | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | MEH1 | YKR007W | Subunit of the EGO/GSE complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | ROM2 | YLR371W | Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | RAD52 | YML032C | Protein involved in homologous recombination | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | PFK2 | YMR205C | Beta subunit of heterooctameric phosphofructokinase | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | NST1 | YNL091W | Translational inhibitor and suppressor of proteasome-assembly defects | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | AIM4 | YBR194W | Protein proposed to be associated with the nuclear pore complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | INP52 | YNL106C | Polyphosphatidylinositol phosphatase | physical | 2 | 2 | 1 | Affinity Capture-Western, Two-hybrid | 
            
                | SSA2 | YLL024C | HSP70 family ATP-binding protein | physical | 2 | 1 | 1 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | SSE1 | YPL106C | ATPase component of heat shock protein Hsp90 chaperone complex | physical | 2 | 1 | 1 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | SWF1 | YDR126W | Palmitoyltransferase that acts on transmembrane proteins | genetic | 2 | 1 | 1 | Negative Genetic, Negative Genetic | 
            
                | CYT1 | YOR065W | Cytochrome c1 | genetic | 2 | 1 | 1 | Negative Genetic, Negative Genetic | 
            
                | RPD3 | YNL330C | Histone deacetylase, component of both the Rpd3S and Rpd3L complexes | genetic | 2 | 1 | 1 | Dosage Lethality, Dosage Lethality | 
            
                | CDC28 | YBR160W | Cyclin-dependent kinase (CDK) catalytic subunit | regulation | 1 | 1 | 1 | quantitative mass spectrometry evidence | 
            
                | PDR1 | YGL013C | Transcription factor that regulates the pleiotropic drug response | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | OPI1 | YHL020C | Transcriptional regulator of a variety of genes | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | GZF3 | YJL110C | GATA zinc finger protein | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | APC1 | YNL172W | Largest subunit of the Anaphase-Promoting Complex/Cyclosome | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | BMH2 | YDR099W | 14-3-3 protein, minor isoform | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CAP1 | YKL007W | Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | RVS167 | YDR388W | Calmodulin-binding actin-associated protein | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | BZZ1 | YHR114W | SH3 domain protein implicated in regulating actin polymerization | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SHO1 | YER118C | Transmembrane osmosensor for filamentous growth and HOG pathways | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | HSE1 | YHL002W | Subunit of the endosomal Vps27p-Hse1p complex | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | HSP82 | YPL240C | Hsp90 chaperone | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SAW1 | YAL027W | 5'- and 3'-flap DNA binding protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SAT4 | YCR008W | Ser/Thr protein kinase involved in salt tolerance, nutrient response | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | MLC1 | YGL106W | Essential light chain for Myo1p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SGV1 | YPR161C | Cyclin (Bur2p)-dependent protein kinase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | PTC7 | YHR076W | Type 2C serine/threonine protein phosphatase (PP2C) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SEC14 | YMR079W | Phosphatidylinositol/phosphatidylcholine transfer protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CDC33 | YOL139C | Translation initiation factor eIF4E | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | POB3 | YML069W | Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CMK1 | YFR014C | Calmodulin-dependent protein kinase | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | SNF1 | YDR477W | AMP-activated S/T protein kinase | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | SNF1 | YDR477W | AMP-activated S/T protein kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TPK1 | YJL164C | cAMP-dependent protein kinase catalytic subunit | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | VAM7 | YGL212W | Vacuolar SNARE protein | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | VPS17 | YOR132W | Subunit of the membrane-associated retromer complex | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | IQG1 | YPL242C | Actin filament binding protein that enhances actin ring formation | physical | 1 | 1 | 1 | FRET | 
            
                | HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | PIN3 | YPR154W | Negative regulator of actin nucleation-promoting factor activity | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | GTS1 | YGL181W | Protein involved in Arf3p regulation and in transcription regulation | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | LAS17 | YOR181W | Actin assembly factor | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | LAS17 | YOR181W | Actin assembly factor | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CMR1 | YDL156W | Nuclear protein with role in transcription, protein quality control | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | PAT1 | YCR077C | Deadenylation-dependent mRNA-decapping factor | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | CRM1 | YGR218W | Nuclear export factor, exportin | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | ISW1 | YBR245C | ATPase subunit of imitation-switch (ISWI) class chromatin remodelers | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | MPT5 | YGL178W | mRNA-binding protein of the PUF family | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | MOG1 | YJR074W | Conserved nuclear protein that interacts with GTP-Gsp1p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CDC28 | YBR160W | Cyclin-dependent kinase (CDK) catalytic subunit | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | CAF20 | YOR276W | Phosphoprotein of the mRNA cap-binding complex | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | PUB1 | YNL016W | Poly (A)+ RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SPT16 | YGL207W | Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CDC37 | YDR168W | Essential Hsp90p co-chaperone | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | PGA3 | YML125C | Putative cytochrome b5 reductase, localized to the plasma membrane | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YDL180W | YDL180W | Putative protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | IMO32 | YGR031W | Conserved mitochondrial protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CBT1 | YKL208W | Protein involved in 5' RNA end processing | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YPT7 | YML001W | Rab family GTPase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SSO2 | YMR183C | Plasma membrane t-SNARE | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | EAF3 | YPR023C | Component of the Rpd3S histone deacetylase complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RIC1 | YLR039C | Protein involved in retrograde transport to the cis-Golgi network | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MDM31 | YHR194W | Mitochondrial protein that may have a role in phospholipid metabolism | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MRM2 | YGL136C | Mitochondrial 2' O-ribose methyltransferase | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | IRA2 | YOL081W | GTPase-activating protein | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | PCF11 | YDR228C | mRNA 3' end processing factor | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HYP2 | YEL034W | Translation elongation factor eIF-5A | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CDC123 | YLR215C | Assembly factor for the eIF2 translation initiation factor complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SGT1 | YOR057W | Cochaperone protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YAR066W | YAR066W | Putative GPI protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YBR284W | YBR284W | Putative metallo-dependent hydrolase superfamily protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MRX14 | YDR115W | Putative mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | OSH7 | YHR001W | Oxysterol-binding phosphatidylserine transferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PTH1 | YHR189W | One of two mitochondrially-localized peptidyl-tRNA hydrolases | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPL40A | YIL148W | Ubiquitin-ribosomal 60S subunit protein L40A fusion protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PET130 | YJL023C | Protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | COA3 | YJL062W-A | Mitochondrial protein required for cytochrome c oxidase assembly | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MNL2 | YLR057W | Putative mannosidase involved in ER-associated protein degradation | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UPS2 | YLR168C | Mitochondrial intermembrane space protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YMR230W-A | YMR230W-A | Putative protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PET494 | YNR045W | Mitochondrial translational activator specific for the COX3 mRNA | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | IMG2 | YCR071C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SLM3 | YDL033C | tRNA-specific 2-thiouridylase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PMP3 | YDR276C | Small plasma membrane protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | OMS1 | YDR316W | Protein integral to the mitochondrial membrane | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PET122 | YER153C | Mitochondrial translational activator specific for the COX3 mRNA | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | LPD1 | YFL018C | Dihydrolipoamide dehydrogenase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPL24A | YGL031C | Ribosomal 60S subunit protein L24A | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SMI1 | YGR229C | Protein involved in the regulation of cell wall synthesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MPC3 | YGR243W | Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GSH1 | YJL101C | Gamma glutamylcysteine synthetase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SMT1 | YJL147C | Translational repressor of the mitochondrial ATP6/8 mRNA | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ILM1 | YJR118C | Protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RAD27 | YKL113C | 5' to 3' exonuclease, 5' flap endonuclease | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VPS9 | YML097C | Guanine nucleotide exchange factor (GEF) and ubiquitin receptor | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RTC1 | YOL138C | Subunit of SEACAT, a subcomplex of the SEA complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | WHI2 | YOR043W | Negative regulator of TORC1 in response to limiting leucine | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VHS3 | YOR054C | Negative regulatory subunit of protein phosphatase 1 Ppz1p | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | COX10 | YPL172C | Heme A:farnesyltransferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TUB4 | YLR212C | Gamma-tubulin | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | HRQ1 | YDR291W | 3'-5' DNA helicase of the conserved RecQ family | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SGS1 | YMR190C | RecQ family nucleolar DNA helicase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ATS1 | YAL020C | Protein required for modification of wobble nucleosides in tRNA | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BCS1 | YDR375C | Protein translocase and chaperone required for Complex III assembly | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BET4 | YJL031C | Alpha subunit of Type II geranylgeranyltransferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | AIM23 | YJL131C | Mitochondrial translation initiation factor 3 (IF3, mIF3) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ATP23 | YNR020C | Putative metalloprotease of the mitochondrial inner membrane | genetic | 1 | 1 | 1 | Negative Genetic |