RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
genetic |
6 |
2 |
4 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue |
HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
genetic |
4 |
3 |
3 |
Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
RQC1 |
YDR333C |
Component of the ribosome quality control complex (RQC) |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement |
HTB1 |
YDR224C |
Histone H2B |
genetic |
3 |
1 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
RQC1 |
YDR333C |
Component of the ribosome quality control complex (RQC) |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Phenotypic Suppression |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement |
DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
HSP104 |
YLL026W |
Disaggregase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Rescue |
RPL22B |
YFL034C-A |
Ribosomal 60S subunit protein L22A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL37B |
YDR500C |
Ribosomal 60S subunit protein L37B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL32 |
YBL092W |
Ribosomal 60S subunit protein L32 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL26B |
YGR034W |
Ribosomal 60S subunit protein L26B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL18B |
YNL301C |
Ribosomal 60S subunit protein L18B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL36B |
YPL249C-A |
Ribosomal 60S subunit protein L36B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL42B |
YHR141C |
Ribosomal 60S subunit protein L42B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Co-fractionation |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
physical |
1 |
1 |
1 |
Two-hybrid |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MRPL8 |
YJL063C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Positive Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAS1 |
YJL149W |
Putative SCF ubiquitin ligase F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCL6 |
YER059W |
Pho85p cyclin of the Pho80p subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
HFM1 |
YGL251C |
Meiosis specific DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OSH6 |
YKR003W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RNQ1 |
YCL028W |
[PIN(+)] prion |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI80 |
YOR143C |
Thiamine pyrophosphokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RQT4 |
YKR023W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MMO1 |
YKL044W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |