COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
5 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Rescue |
COX2 |
Q0250 |
Subunit II of cytochrome c oxidase (Complex IV) |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Positive Genetic, Synthetic Growth Defect |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
3 |
2 |
3 |
Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
SAL1 |
YNL083W |
ADP/ATP transporter |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Growth Defect |
AAC1 |
YMR056C |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Enhancement |
QCR10 |
YHR001W-A |
Subunit of the ubiqunol-cytochrome c oxidoreductase complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Dosage Rescue |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
CYT1 |
YOR065W |
Cytochrome c1 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NRG1 |
YDR043C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HAP4 |
YKL109W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP123 |
YER110C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
genetic |
1 |
1 |
1 |
Dosage Rescue |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ADH2 |
YMR303C |
Glucose-repressible alcohol dehydrogenase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAC1 |
YMR056C |
Mitochondrial inner membrane ADP/ATP translocator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCO2 |
YBR024W |
Protein anchored to mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIC2 |
YER053C |
Mitochondrial copper and phosphate carrier |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TIM44 |
YIL022W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TIM17 |
YJL143W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC22 |
YLR268W |
R-SNARE protein |
physical |
1 |
1 |
1 |
PCA |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Dosage Rescue |
URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
physical |
1 |
1 |
1 |
PCA |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PGS1 |
YCL004W |
Phosphatidylglycerolphosphate synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TAZ1 |
YPR140W |
Lyso-phosphatidylcholine acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOL3 |
YHR163W |
6-phosphogluconolactonase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SAF1 |
YBR280C |
F-Box protein involved in proteasome-dependent degradation of Aah1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RGI1 |
YER067W |
Protein involved in energy metabolism under respiratory conditions |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SSY5 |
YJL156C |
Serine protease of SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SDD2 |
YMR074C |
Protein with homology to human PDCD5 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TMA7 |
YLR262C-A |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MAE1 |
YKL029C |
Mitochondrial malic enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HEM15 |
YOR176W |
Ferrochelatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN2 |
YLR096W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ACS1 |
YAL054C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMG2 |
YLR450W |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP10 |
YER182W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCP1 |
YKR066C |
Mitochondrial cytochrome-c peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COB |
Q0105 |
Cytochrome b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASN1 |
YPR145W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASN2 |
YGR124W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP17 |
YDR377W |
Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCV3 |
YAL044C |
H subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NDE2 |
YDL085W |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMS1 |
YMR020W |
Polyamine oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Positive Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GGC1 |
YDL198C |
Mitochondrial GTP/GDP transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GGC1 |
YDL198C |
Mitochondrial GTP/GDP transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NSG1 |
YHR133C |
Protein involved in regulation of sterol biosynthesis |
physical |
1 |
1 |
1 |
PCA |
CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OM14 |
YBR230C |
Mitochondrial outer membrane receptor for cytosolic ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BXI1 |
YNL305C |
Protein involved in apoptosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
INO1 |
YJL153C |
Inositol-3-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLD1 |
YDL174C |
Major mitochondrial D-lactate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FSF1 |
YOR271C |
Putative protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX13 |
YGL191W |
Subunit VIa of cytochrome c oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIC60 |
YKR016W |
Component of the MICOS complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATH1 |
YPR026W |
Acid trehalase required for utilization of extracellular trehalose |
genetic |
1 |
1 |
1 |
Positive Genetic |
APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX8 |
YLR395C |
Subunit VIII of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IAH1 |
YOR126C |
Isoamyl acetate-hydrolyzing esterase |
genetic |
1 |
1 |
1 |
Positive Genetic |