| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
3 |
3 |
3 |
Dosage Rescue, Phenotypic Suppression, Synthetic Rescue |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
3 |
1 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
3 |
3 |
2 |
Biochemical Activity, Affinity Capture-Western, Co-localization |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Phenotypic Enhancement |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
regulation |
1 |
1 |
1 |
sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOP1 |
YPR028W |
Reticulon-interacting protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR087C-A |
YCR087C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHL026C |
YHL026C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR210C |
YHR210C |
Putative aldose 1-epimerase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAX4 |
YJL083W |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL3 |
YIR032C |
Ureidoglycolate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG1 |
YGR175C |
Squalene epoxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH203 |
YLR154C |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET191 |
YJR034W |
Protein required for assembly of cytochrome c oxidase |
physical |
1 |
1 |
1 |
PCA |
| PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMA17 |
YIL029C |
Protein involved in targeting mitochondrial membrane protein precursor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOK1 |
YDR006C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPN1 |
YDR452W |
Dual endo- and exopolyphosphatase with a role in phosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERP5 |
YHR110W |
Protein with similarity to Emp24p and Erv25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PHO90 |
YJL198W |
Low-affinity phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX41 |
YDR425W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RQT4 |
YKR023W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSH6 |
YKR003W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCY2 |
YER056C |
Purine-cytosine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE9 |
YJL174W |
Glycoprotein involved in cell wall beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSF1 |
YOR271C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMY2 |
YBR172C |
GYF domain protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PFF1 |
YBR074W |
Multi-spanning vacuolar membrane protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO3 |
YBR092C |
Constitutively expressed acid phosphatase similar to Pho5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC6 |
YHR151C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRT13 |
YER066W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
