Standard name Systematic name Name description Description
ZUO1 YGR285C Ribosome-associated chaperone Ribosome-associated chaperone; zuotin functions in ribosome biogenesis and as a chaperone for nascent polypeptide chains in partnership with Ssz1p and SSb1/2; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p; human gene DNAJC2 can partially complement yeast zuo1 null mutant
Visualize the interactome of ZUO1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 0.988 0.975

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 86400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ZUO1 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 15 5 12 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Co-crystal Structure
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 4 3 3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 4 2 3 Dosage Rescue, Synthetic Growth Defect, Dosage Rescue, Dosage Rescue
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 2 2 Affinity Capture-MS, Co-purification
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
AMN1 YBR158W Modulator of cell separation and mitotic exit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) genetic 2 1 2 Dosage Rescue, Dosage Rescue
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SKI3 YPR189W Ski complex component and TPR protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 2 1 2 Two-hybrid, Two-hybrid
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 2 1 2 Positive Genetic, Positive Genetic
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system genetic 2 1 2 Negative Genetic, Negative Genetic
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 2 1 2 Positive Genetic, Positive Genetic
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 2 2 1 Synthetic Growth Defect, Phenotypic Suppression
RPL31B YLR406C Ribosomal 60S subunit protein L31B physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Synthetic Rescue
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Synthetic Rescue
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-Western
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Synthetic Lethality
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Rescue
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Rescue
BUD14 YAR014C Protein involved in bud-site selection physical 1 1 1 Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export physical 1 1 1 Affinity Capture-Western
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 PCA
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Synthetic Rescue
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-Western
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Positive Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Rescue
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-MS
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Dosage Rescue
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
SGD1 YLR336C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Lethality
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Phenotypic Enhancement
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Lethality
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 1 1 1 Positive Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Lethality
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase genetic 1 1 1 Synthetic Rescue
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Synthetic Rescue
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Rescue
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Phenotypic Enhancement
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Positive Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Positive Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Dosage Rescue
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Synthetic Rescue
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Reconstituted Complex
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 1 1 1 PCA
MET4 YNL103W Leucine-zipper transcriptional activator physical 1 1 1 Two-hybrid
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Two-hybrid
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin genetic 1 1 1 Phenotypic Suppression
SOK1 YDR006C Protein of unknown function physical 1 1 1 Affinity Capture-MS
LYS4 YDR234W Homoaconitase physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
YPT6 YLR262C Rab family GTPase physical 1 1 1 Affinity Capture-MS
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Rescue
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Suppression
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Affinity Capture-Western
MPA43 YNL249C Protein of unknown function genetic 1 1 1 Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Synthetic Growth Defect
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RTT106 YNL206C Histone chaperone genetic 1 1 1 Synthetic Lethality
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Positive Genetic
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Biochemical Activity
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Dosage Rescue
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Positive Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
TAE1 YBR261C AdoMet-dependent proline methyltransferase genetic 1 1 1 Synthetic Growth Defect
EMA19 YLR050C Integral ER membrane protein involved in protein sorting genetic 1 1 1 Positive Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Negative Genetic
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 1 1 1 Negative Genetic
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex genetic 1 1 1 Dosage Rescue
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
OPT2 YPR194C Oligopeptide transporter genetic 1 1 1 Synthetic Lethality
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Synthetic Growth Defect
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Dosage Rescue
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Dosage Rescue