| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
8 |
1 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
8 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
8 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
7 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
| PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
physical |
6 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
physical |
6 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
physical |
5 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
4 |
3 |
4 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic |
| MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| SMD3 |
YLR147C |
Core Sm protein Sm D3 |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| MSL5 |
YLR116W |
Component of commitment complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PAB1 |
YER165W |
Poly(A) binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| SPO13 |
YHR014W |
Meiotic regulator |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Phenotypic Suppression |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSH155 |
YMR288W |
U2-snRNP associated splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD3 |
YLR147C |
Core Sm protein Sm D3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
physical |
1 |
1 |
1 |
Two-hybrid |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
physical |
1 |
1 |
1 |
Co-purification |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX2 |
YFL017W-A |
Core Sm protein Sm G |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMX2 |
YFL017W-A |
Core Sm protein Sm G |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SME1 |
YOR159C |
Core Sm protein Sm E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWT21 |
YNL187W |
Protein involved in mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWT21 |
YNL187W |
Protein involved in mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RBS1 |
YDL189W |
Protein involved in assembly of the RNA Pol III complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF5 |
YPR041W |
Translation initiation factor eIF5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCH2 |
YBR186W |
Hexameric ring ATPase that remodels chromosome axis protein Hop1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OM14 |
YBR230C |
Mitochondrial outer membrane receptor for cytosolic ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YEL025C |
YEL025C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX21 |
YGR239C |
Peroxin required for peroxisomal matrix protein targeting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR130C |
YGR130C |
Component of the eisosome with unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR283W |
YOR283W |
Phosphatase with a broad substrate specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL118W |
YJL118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKG1 |
YKR100C |
Transmembrane protein with a role in cell wall polymer composition |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WTM1 |
YOR230W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBD2 |
YPL246C |
Possible rhomboid protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN3 |
YPR154W |
Negative regulator of actin nucleation-promoting factor activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FZF1 |
YGL254W |
Transcription factor involved in sulfite metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EBS1 |
YDR206W |
Protein involved in translation inhibition and nonsense-mediated decay |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COX1 |
Q0045 |
Subunit I of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HFM1 |
YGL251C |
Meiosis specific DNA helicase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MEI4 |
YER044C-A |
Meiosis-specific protein involved in forming DSBs |
physical |
1 |
1 |
1 |
Two-hybrid |
| COB |
Q0105 |
Cytochrome b |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MSL5 |
YLR116W |
Component of commitment complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRN1 |
YGR093W |
Splicing factor that modulates turnover of branched RNAs by Dbr1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP46 |
YKR049C |
Putative redox protein containing a thioredoxin fold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA1 |
YMR316W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUP1-1 |
YHR053C |
Metallothionein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GRE1 |
YPL223C |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Positive Genetic |