Standard name Systematic name Name description Description
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication
Visualize the interactome of PDR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.053 0.060 NaN
Nucleus 0.935 0.872 0.877
Mito NaN 0.474 0.572

GFP localization & abundance

GFP localization GFP abundance
nucleus 1300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PDR1 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 13 2 13 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes physical 5 3 2 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, PCA
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter genetic 4 2 4 Synthetic Growth Defect, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex physical 4 3 2 Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western
ERG3 YLR056W C-5 sterol desaturase genetic 3 3 3 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 3 2 3 Positive Genetic, Synthetic Growth Defect, Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 2 2 Negative Genetic, Negative Genetic, Phenotypic Enhancement
CHL1 YPL008W Probable DNA helicase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter regulation 2 2 2 beta-galactosidase reporter gene assay evidence, northern blot evidence
BMH1 YER177W 14-3-3 protein, major isoform genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter regulation 2 1 2 northern blot evidence, northern blot evidence
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 2 Negative Genetic, Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 2 1 2 Negative Genetic, Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 2 1 2 Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
DUG1 YFR044C Cys-Gly metallo-di-peptidase genetic 2 1 2 Negative Genetic, Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 2 1 2 Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 2 Positive Genetic, Positive Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 2 1 2 Positive Genetic, Positive Genetic
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family genetic 2 1 2 Negative Genetic, Negative Genetic
ZUO1 YGR285C Ribosome-associated chaperone physical 2 1 2 Two-hybrid, Two-hybrid
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 2 1 2 Negative Genetic, Negative Genetic
RPS26B YER131W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 2 1 2 Negative Genetic, Negative Genetic
YGR237C YGR237C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 2 1 2 Negative Genetic, Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 2 1 2 Negative Genetic, Negative Genetic
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family genetic 2 1 2 Negative Genetic, Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 2 1 2 Negative Genetic, Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 2 1 2 Negative Genetic, Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 2 1 2 Positive Genetic, Positive Genetic
MIL1 YFL034W Predicted lipase genetic 2 1 2 Negative Genetic, Negative Genetic
DAL4 YIR028W Allantoin permease genetic 2 1 2 Negative Genetic, Negative Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor regulation 2 2 1 beta-galactosidase reporter gene assay evidence, RNA protection assay evidence
ELM1 YKL048C Serine/threonine protein kinase genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
STB5 YHR178W Transcription factor physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
ZUO1 YGR285C Ribosome-associated chaperone genetic 2 2 1 Synthetic Growth Defect, Phenotypic Suppression
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 1 Negative Genetic, Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
DFG16 YOR030W Probable multiple transmembrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRG1 YDR043C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity regulation 1 1 1 DNA to cDNA expression microarray evidence
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting regulation 1 1 1 DNA to cDNA expression microarray evidence
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATG40 YOR152C Autophagy receptor with a role in endoplasmic reticulum degradation regulation 1 1 1 DNA to cDNA expression microarray evidence
SRV2 YNL138W CAP (cyclase-associated protein) regulation 1 1 1 DNA to cDNA expression microarray evidence
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR102W YOR102W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YPR197C YPR197C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
FRE1 YLR214W Ferric reductase and cupric reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
GCY1 YOR120W Glycerol dehydrogenase regulation 1 1 1 DNA to cDNA expression microarray evidence
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation regulation 1 1 1 DNA to cDNA expression microarray evidence
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase regulation 1 1 1 DNA to cDNA expression microarray evidence
YER134C YER134C Magnesium-dependent acid phosphatase regulation 1 1 1 DNA to cDNA expression microarray evidence
FPR2 YDR519W Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) regulation 1 1 1 DNA to cDNA expression microarray evidence
MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
TIS11 YLR136C mRNA-binding protein expressed during iron starvation regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL134C YNL134C NADH-dependent aldehyde reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
NRK1 YNL129W Nicotinamide riboside kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase regulation 1 1 1 DNA to cDNA expression microarray evidence
PRM7 YDL039C Pheromone-regulated protein regulation 1 1 1 DNA to cDNA expression microarray evidence
ATG18 YFR021W Phosphoinositide binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SPG3 YDR504C Protein required for high temperature survival during stationary phase regulation 1 1 1 DNA to cDNA expression microarray evidence
RUP1 YOR138C Protein that regulates ubiquitination of Rsp5p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAD55 YDR076W Protein that stimulates strand exchange regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR444W YDR444W Putative hydrolase acting on ester bonds regulation 1 1 1 DNA to cDNA expression microarray evidence
YKL097C YKL097C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL193W YNL193W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR262W YDR262W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YBR225W YBR225W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR035C YGR035C Putative protein of unknown function, potential Cdc28p substrate regulation 1 1 1 DNA to cDNA expression microarray evidence
HXT13 YEL069C Putative transmembrane polyol transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR034C-D YDR034C-D Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 DNA to cDNA expression microarray evidence
YPR158C-C YPR158C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
RPC53 YDL150W RNA polymerase III subunit C53 regulation 1 1 1 DNA to cDNA expression microarray evidence
RPC82 YPR190C RNA polymerase III subunit C82 regulation 1 1 1 DNA to cDNA expression microarray evidence
RPO26 YPR187W RNA polymerase subunit ABC23 regulation 1 1 1 DNA to cDNA expression microarray evidence
SNT1 YCR033W Set3C histone deacetylase scaffold regulation 1 1 1 DNA to cDNA expression microarray evidence
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p regulation 1 1 1 DNA to cDNA expression microarray evidence
NFI1 YOR156C SUMO E3 ligase regulation 1 1 1 DNA to cDNA expression microarray evidence
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network regulation 1 1 1 beta-galactosidase reporter gene assay evidence
SFL1 YOR140W Transcriptional repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADA2 YDR448W Transcription coactivator regulation 1 1 1 DNA to cDNA expression microarray evidence
RCE1 YMR274C Type II CAAX prenyl protease regulation 1 1 1 DNA to cDNA expression microarray evidence
UBP2 YOR124C Ubiquitin-specific protease regulation 1 1 1 DNA to cDNA expression microarray evidence
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Synthetic Growth Defect
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Phenotypic Enhancement
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Phenotypic Enhancement
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Phenotypic Enhancement
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Phenotypic Enhancement
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Phenotypic Enhancement
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 1 1 1 Phenotypic Enhancement
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Phenotypic Enhancement
ARP10 YDR106W Component of the dynactin complex genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Phenotypic Suppression
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Negative Genetic
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Dosage Rescue
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering physical 1 1 1 Two-hybrid
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network physical 1 1 1 Co-fractionation
PRC1 YMR297W Vacuolar carboxypeptidase Y (proteinase C, CPY) physical 1 1 1 Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 1 1 1 Reconstituted Complex
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Two-hybrid
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) genetic 1 1 1 Phenotypic Enhancement
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PHO80 YOL001W Cyclin physical 1 1 1 PCA
PHO80 YOL001W Cyclin genetic 1 1 1 Dosage Lethality
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 PCA
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Two-hybrid
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Phenotypic Suppression
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
RPL31B YLR406C Ribosomal 60S subunit protein L31B genetic 1 1 1 Negative Genetic
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Negative Genetic
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Synthetic Growth Defect
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
PPS1 YBR276C Protein phosphatase genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Phenotypic Enhancement
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Phenotypic Enhancement
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Phenotypic Enhancement
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Phenotypic Enhancement
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Phenotypic Enhancement
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Phenotypic Enhancement
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Phenotypic Enhancement
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Phenotypic Enhancement
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Positive Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Positive Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Negative Genetic
RPL27B YDR471W Ribosomal 60S subunit protein L27B genetic 1 1 1 Negative Genetic
YDR514C YDR514C Protein of unknown function that localizes to mitochondria genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Negative Genetic
YPR078C YPR078C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUE1 YPR151C Protein required for degradation of unstable forms of cytochrome c genetic 1 1 1 Negative Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Positive Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Positive Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Negative Genetic
CWH43 YCR017C GPI lipid remodelase genetic 1 1 1 Phenotypic Enhancement
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Phenotypic Enhancement
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 1 1 1 Phenotypic Enhancement
IGO2 YHR132W-A Protein required for initiation of G0 program genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Phenotypic Enhancement
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Negative Genetic
MIN10 YFR032C-B Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic