Standard name Systematic name Name description Description
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily Low-affinity glucose transporter of the major facilitator superfamily; expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting; HXT1 has a paralog, HXT6, what arose from the whole genome duplication
Visualize the interactome of HXT1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 23300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HXT1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1910 (L-sorbose transport), r_1166 (glucose transport), r_4395 (D-tagatose uptake via diffusion), r_1139 (D-mannose transport), r_1134 (D-fructose transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 4 2 4 Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 3 2 2 Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system genetic 3 2 2 Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue
AEP2 YMR282C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ATG8 YBL078C Ub-like protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RGT1 YKL038W Glucose-responsive transcription factor regulation 2 2 2 beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence
GAL2 YLR081W Galactose permease genetic 2 2 2 Synthetic Rescue, Positive Genetic
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 2 2 2 PCA, Affinity Capture-Western
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 2 2 2 Protein-RNA, Affinity Capture-RNA
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 2 2 Dosage Rescue, Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 2 1 2 Negative Genetic, Negative Genetic
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 2 1 2 Negative Genetic, Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 2 1 2 PCA, PCA
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 2 1 2 Dosage Rescue, Dosage Rescue
PLB1 YMR008C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 2 1 2 Negative Genetic, Negative Genetic
JLP2 YMR132C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
AIM24 YJR080C Protein with a role in determining mitochondrial architecture genetic 2 1 2 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 beta-galactosidase reporter gene assay evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 beta-galactosidase reporter gene assay evidence
WTM1 YOR230W Transcriptional modulator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ROX1 YPR065W Heme-dependent repressor of hypoxic genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
FTH1 YBR207W Putative high affinity iron transporter physical 1 1 1 PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 PCA
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex genetic 1 1 1 Dosage Rescue
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 PCA
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Dosage Rescue
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 PCA
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) physical 1 1 1 PCA
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 1 1 1 Phenotypic Enhancement
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Proximity Label-MS
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis physical 1 1 1 PCA
ELO3 YLR372W Elongase physical 1 1 1 PCA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
GTT1 YIR038C ER associated glutathione S-transferase physical 1 1 1 PCA
APN2 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage genetic 1 1 1 Negative Genetic
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
ASN2 YGR124W Asparagine synthetase genetic 1 1 1 Positive Genetic
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase genetic 1 1 1 Positive Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease physical 1 1 1 PCA
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Co-fractionation
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Co-fractionation
RFS1 YBR052C Protein of unknown function physical 1 1 1 PCA
SNA4 YDL123W Protein of unknown function physical 1 1 1 PCA
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
TVP15 YDR100W Integral membrane protein physical 1 1 1 PCA
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking physical 1 1 1 PCA
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain physical 1 1 1 PCA
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 PCA
SEC4 YFL005W Rab family GTPase physical 1 1 1 PCA
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions physical 1 1 1 PCA
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 PCA
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
SNA3 YJL151C Protein involved in efficient MVB sorting of proteins to the vacuole physical 1 1 1 PCA
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Phenotypic Enhancement
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
YVH1 YIR026C Dual specificity protein phosphatase physical 1 1 1 PCA
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 PCA
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
SHR3 YDL212W Endoplasmic reticulum packaging chaperone physical 1 1 1 PCA
YET1 YKL065C Endoplasmic reticulum transmembrane protein physical 1 1 1 PCA
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase physical 1 1 1 PCA
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit physical 1 1 1 PCA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 PCA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 PCA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Rescue
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Phenotypic Enhancement
HXT4 YHR092C High-affinity glucose transporter genetic 1 1 1 Phenotypic Enhancement
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Phenotypic Enhancement
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Phenotypic Enhancement
HXT7 YDR342C High-affinity glucose transporter genetic 1 1 1 Phenotypic Enhancement
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 1 1 1 Positive Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Negative Genetic
SAM2 YDR502C S-adenosylmethionine synthetase genetic 1 1 1 Negative Genetic
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Positive Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
LEU9 YOR108W Alpha-isopropylmalate synthase II (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Negative Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
YGR016W YGR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Negative Genetic
RBH1 YJL181W Putative protein of unknown function genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
YML100W-A YML100W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
BAP2 YBR068C High-affinity leucine permease physical 1 1 1 PCA
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole physical 1 1 1 PCA