GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
LTV1	YKL143W	Subunit of the EGO/GSE complex	physical	18	5	16	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-fractionation, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS
TSR1	YDL060W	Protein required for processing of 20S pre-rRNA in the cytoplasm	physical	18	2	14	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RIO2	YNL207W	Essential serine kinase involved in the processing of 20S pre-rRNA	physical	17	5	13	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
KRR1	YCL059C	Nucleolar protein required for rRNA synthesis and ribosomal assembly	physical	13	3	10	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid
NOB1	YOR056C	Protein involved in proteasomal and 40S ribosomal subunit biogenesis	physical	13	2	9	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
NOC4	YPR144C	Nucleolar protein	physical	12	2	9	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UTP22	YGR090W	Component of the small-subunit processome	physical	12	3	8	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
RRP12	YPL012W	Protein required for export of the ribosomal subunits	physical	11	2	10	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP14	YDL148C	Nucleolar protein	physical	10	3	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid
SLX9	YGR081C	Protein required for pre-rRNA processing	physical	9	4	9	Affinity Capture-MS, Affinity Capture-MS, PCA, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
RPS3	YNL178W	Protein component of the small (40S) ribosomal subunit	physical	9	3	9	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	physical	9	3	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-Western, Affinity Capture-MS
KRE33	YNL132W	Acetyltransferase required for biogenesis of small ribosomal subunit	physical	9	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP1	YDL014W	Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus	physical	8	2	8	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
IMP4	YNL075W	Component of the SSU processome	physical	8	3	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
ECM16	YMR128W	Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP	physical	8	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PNO1	YOR145C	Essential nucleolar protein required for pre-18S rRNA processing	physical	8	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
PWP2	YCR057C	Conserved 90S pre-ribosomal component	physical	8	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS14A	YCR031C	Protein component of the small (40S) ribosomal subunit	physical	7	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS8A	YBL072C	Protein component of the small (40S) ribosomal subunit	physical	7	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP5	YMR229C	RNA binding protein involved in synthesis of 18S and 5.8S rRNAs	physical	7	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DIM1	YPL266W	Essential 18S rRNA dimethylase (dimethyladenosine transferase)	physical	7	2	7	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
IMP3	YHR148W	Component of the SSU processome	physical	7	3	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
UTP10	YJL109C	Nucleolar protein	physical	7	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UTP7	YER082C	Nucleolar protein	physical	6	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RCL1	YOL010W	Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis	physical	6	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
UTP20	YBL004W	Component of the small-subunit (SSU) processome	physical	6	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS13	YDR064W	Protein component of the small (40S) ribosomal subunit	physical	6	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS17A	YML024W	Ribosomal protein 51 (rp51) of the small (40s) subunit	physical	6	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS5	YJR123W	Protein component of the small (40S) ribosomal subunit	physical	6	2	5	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
CBF5	YLR175W	Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
BMS1	YPL217C	GTPase required for ribosomal subunit synthesis and rRNA processing	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
EMG1	YLR186W	Methyltransferase for rRNA	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
MPP10	YJR002W	Component of the SSU processome and 90S preribosome	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
SOF1	YLL011W	Protein required for biogenesis of 40S (small) ribosomal subunit	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
UTP6	YDR449C	Nucleolar protein	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
UTP15	YMR093W	Nucleolar protein	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPS18A	YDR450W	Protein component of the small (40S) ribosomal subunit	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS1B	YML063W	Ribosomal protein of the small (40S) subunit	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS4A	YJR145C	Protein component of the small (40S) ribosomal subunit	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS9B	YBR189W	Protein component of the small (40S) ribosomal subunit	physical	5	2	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
UTP4	YDR324C	Subunit of U3-containing 90S preribosome and SSU processome complexes	physical	5	1	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS6A	YPL090C	Protein component of the small (40S) ribosomal subunit	physical	5	2	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
ENP1	YBR247C	Protein associated with U3 and U14 snoRNAs	physical	4	3	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid
DIP2	YLR129W	Nucleolar protein	physical	4	2	4	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPS11B	YBR048W	Protein component of the small (40S) ribosomal subunit	physical	4	2	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPS17B	YDR447C	Ribosomal protein 51 (rp51) of the small (40s) subunit	physical	4	2	4	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPS7A	YOR096W	Protein component of the small (40S) ribosomal subunit	physical	4	2	4	Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SLX9	YGR081C	Protein required for pre-rRNA processing	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPL17A	YKL180W	Ribosomal 60S subunit protein L17A	physical	3	2	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPS22B	YLR367W	Protein component of the small (40S) ribosomal subunit	physical	3	2	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPS24A	YER074W	Protein component of the small (40S) ribosomal subunit	physical	3	2	3	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPS4B	YHR203C	Protein component of the small (40S) ribosomal subunit	physical	3	2	3	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPS8B	YER102W	Protein component of the small (40S) ribosomal subunit	physical	3	2	3	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HAS1	YMR290C	ATP-dependent RNA helicase	physical	3	2	3	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
UTP21	YLR409C	Subunit of U3-containing 90S preribosome and SSU processome complexes	physical	3	2	3	Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
DBP8	YHR169W	ATPase, putative RNA helicase of the DEAD-box family	physical	3	2	3	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
NOP56	YLR197W	Essential evolutionarily-conserved nucleolar protein	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS0A	YGR214W	Ribosomal 40S subunit protein S0A	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS7B	YNL096C	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS26B	YER131W	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPS1A	YLR441C	Ribosomal protein of the small (40S) subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS2	YGL123W	Protein component of the small (40S) subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS12	YOR369C	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS15	YOL040C	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS20	YHL015W	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS22A	YJL190C	Protein component of the small (40S) ribosomal subunit	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGN1	YIR001C	Cytoplasmic RNA-binding protein	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
BUD21	YOR078W	Component of small ribosomal subunit (SSU) processosome	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PUF4	YGL014W	Member of the PUF protein family	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RRP8	YDR083W	Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NUP188	YML103C	Subunit of the inner ring of the nuclear pore complex (NPC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MDR1	YGR100W	Cytoplasmic GTPase-activating protein	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
RPL10	YLR075W	Ribosomal 60S subunit protein L10	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
RPL11A	YPR102C	Ribosomal 60S subunit protein L11A	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
RPL4A	YBR031W	Ribosomal 60S subunit protein L4A	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
SSB2	YNL209W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	2	2	2	Affinity Capture-MS, Co-purification
ROK1	YGL171W	RNA-dependent ATPase	physical	2	2	2	Affinity Capture-Western, Affinity Capture-MS
SAS10	YDL153C	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	2	2	2	Affinity Capture-MS, Two-hybrid
FCF1	YDR339C	PINc domain endonuclease	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
ESF2	YNR054C	Essential nucleolar protein involved in pre-18S rRNA processing	physical	2	2	2	Affinity Capture-MS, Two-hybrid
PAB1	YER165W	Poly(A) binding protein	genetic	2	2	2	Negative Genetic, Phenotypic Suppression
CHL1	YPL008W	Probable DNA helicase	genetic	2	2	2	Synthetic Lethality, Positive Genetic
BFR2	YDR299W	Component of the SSU and 90S preribosomes	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
CSL4	YNL232W	Exosome non-catalytic core component	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
ASC1	YMR116C	G-protein beta subunit and guanine dissociation inhibitor for Gpa2p	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS11A	YDR025W	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
KRI1	YNL308C	Essential nucleolar protein required for 40S ribosome biogenesis	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS14B	YJL191W	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
MRD1	YPR112C	Essential conserved small ribosomal subunit (40s) synthesis factor	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
FAF1	YIL019W	Protein required for pre-rRNA processing	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
NOP9	YJL010C	Essential subunit of U3-containing 90S preribosome	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
NOP58	YOR310C	Protein involved in producing mature rRNAs and snoRNAs	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS26A	YGL189C	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-Western, Affinity Capture-Western
PRP43	YGL120C	RNA helicase in the DEAH-box family	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
MPT5	YGL178W	mRNA-binding protein of the PUF family	physical	2	1	2	Affinity Capture-RNA, Affinity Capture-RNA
UTP5	YDR398W	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
UTP8	YGR128C	Nucleolar protein required for export of tRNAs from the nucleus	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
UTP18	YJL069C	Small-subunit processome protein involved in pre-18S rRNA maturation	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS6B	YBR181C	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS10A	YOR293W	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS16A	YMR143W	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS18B	YML026C	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPS19A	YOL121C	Protein component of the small (40S) ribosomal subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPL26A	YLR344W	Ribosomal 60S subunit protein L26A	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPL31A	YDL075W	Ribosomal 60S subunit protein L31A	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPL25	YOL127W	Ribosomal 60S subunit protein L25	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RRP6	YOR001W	Nuclear exosome exonuclease component	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RAD51	YER095W	Strand exchange protein	genetic	2	1	2	Negative Genetic, Negative Genetic
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	2	1	2	Negative Genetic, Negative Genetic
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	genetic	2	1	2	Negative Genetic, Negative Genetic
SAC1	YKL212W	Phosphatidylinositol phosphate phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
NUP133	YKR082W	Subunit of Nup84p subcomplex of nuclear pore complex (NPC)	genetic	2	1	2	Negative Genetic, Negative Genetic
UBI4	YLL039C	Ubiquitin	genetic	2	1	2	Negative Genetic, Negative Genetic
RPL37A	YLR185W	Ribosomal 60S subunit protein L37A	genetic	2	1	2	Negative Genetic, Negative Genetic
EOS1	YNL080C	Protein involved in N-glycosylation	genetic	2	1	2	Negative Genetic, Negative Genetic
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	2	1	2	Negative Genetic, Negative Genetic
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	genetic	2	1	2	Negative Genetic, Negative Genetic
BUD21	YOR078W	Component of small ribosomal subunit (SSU) processosome	genetic	2	1	2	Negative Genetic, Negative Genetic
DUF1	YOL087C	Ubiquitin-binding protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
BTS1	YPL069C	Geranylgeranyl diphosphate synthase (GGPPS)	genetic	2	1	2	Negative Genetic, Negative Genetic
RRP36	YOR287C	Component of 90S preribosomes	physical	2	2	1	Two-hybrid, Affinity Capture-Western
DHR2	YKL078W	Predominantly nucleolar DEAH-box ATP-dependent RNA helicase	physical	2	2	1	Two-hybrid, Affinity Capture-Western
DIS3	YOL021C	Exosome core complex catalytic subunit	genetic	2	1	1	Negative Genetic, Negative Genetic
UTP6	YDR449C	Nucleolar protein	genetic	2	1	1	Negative Genetic, Negative Genetic
UTP15	YMR093W	Nucleolar protein	genetic	2	1	1	Negative Genetic, Negative Genetic
HAS1	YMR290C	ATP-dependent RNA helicase	genetic	2	1	1	Negative Genetic, Negative Genetic
UTP14	YML093W	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
RRP42	YDL111C	Exosome non-catalytic core component	genetic	2	1	1	Negative Genetic, Negative Genetic
RRP45	YDR280W	Exosome non-catalytic core component	genetic	2	1	1	Negative Genetic, Negative Genetic
MTR4	YJL050W	RNA duplex-sensing translocase	genetic	2	1	1	Negative Genetic, Negative Genetic
MRT4	YKL009W	Protein involved in mRNA turnover and ribosome assembly	genetic	2	1	1	Negative Genetic, Negative Genetic
UTP9	YHR196W	Nucleolar protein	genetic	2	1	1	Negative Genetic, Negative Genetic
SKI6	YGR195W	Exosome non-catalytic core component	genetic	2	1	1	Negative Genetic, Negative Genetic
MIF2	YKL089W	Centromeric CDEIII region binding protein	genetic	2	1	1	Negative Genetic, Negative Genetic
RNA1	YMR235C	GTPase activating protein (GAP) for Gsp1p	genetic	2	1	1	Negative Genetic, Negative Genetic
DOM34	YNL001W	Protein that facilitates ribosomal subunit dissociation	genetic	2	1	1	Negative Genetic, Negative Genetic
BCD1	YHR040W	Essential protein required for the accumulation of box C/D snoRNA	genetic	2	1	1	Negative Genetic, Negative Genetic
SFP1	YLR403W	Regulates transcription of ribosomal protein and biogenesis genes	regulation	1	1	1	DNA to cDNA expression microarray evidence
IXR1	YKL032C	Transcriptional repressor that regulates hypoxic genes during normoxia	regulation	1	1	1	DNA to cDNA expression microarray evidence
SPT20	YOL148C	Subunit of the SAGA transcriptional regulatory complex	regulation	1	1	1	DNA to cDNA expression microarray evidence
RAD53	YPL153C	DNA damage response kinase	regulation	1	1	1	protein kinase assay evidence
CDC73	YLR418C	Component of the Paf1p complex	genetic	1	1	1	Synthetic Lethality
BRX1	YOL077C	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
DBP9	YLR276C	DEAD-box protein required for 27S rRNA processing	physical	1	1	1	Affinity Capture-MS
DRS1	YLL008W	Nucleolar DEAD-box protein required for ribosome assembly and function	physical	1	1	1	Affinity Capture-MS
EBP2	YKL172W	Required for 25S rRNA maturation and 60S ribosomal subunit assembly	physical	1	1	1	Affinity Capture-MS
CIC1	YHR052W	Essential protein that interacts with proteasome components	physical	1	1	1	Affinity Capture-MS
DBP3	YGL078C	RNA-Dependent ATPase, member of DExD/H-box family	physical	1	1	1	Affinity Capture-MS
CSL4	YNL232W	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
DIS3	YOL021C	Exosome core complex catalytic subunit	physical	1	1	1	Affinity Capture-MS
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
BAT1	YHR208W	Mitochondrial branched-chain amino acid (BCAA) aminotransferase	genetic	1	1	1	Negative Genetic
BDF1	YLR399C	BET family transcriptional regulator	genetic	1	1	1	Positive Genetic
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Dosage Lethality
CEG1	YGL130W	Guanylyltransferase involved in mRNA 5' capping	genetic	1	1	1	Negative Genetic
CTK1	YKL139W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I)	genetic	1	1	1	Negative Genetic
EMG1	YLR186W	Methyltransferase for rRNA	genetic	1	1	1	Negative Genetic
UTP7	YER082C	Nucleolar protein	genetic	1	1	1	Negative Genetic
KRE33	YNL132W	Acetyltransferase required for biogenesis of small ribosomal subunit	genetic	1	1	1	Negative Genetic
SAM1	YLR180W	S-adenosylmethionine synthetase	physical	1	1	1	Affinity Capture-MS
PTC3	YBL056W	Type 2C protein phosphatase (PP2C)	physical	1	1	1	Affinity Capture-MS
PWP2	YCR057C	Conserved 90S pre-ribosomal component	genetic	1	1	1	Negative Genetic
RIO2	YNL207W	Essential serine kinase involved in the processing of 20S pre-rRNA	genetic	1	1	1	Negative Genetic
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	genetic	1	1	1	Negative Genetic
KAP104	YBR017C	Transportin or cytosolic karyopherin beta 2	physical	1	1	1	Affinity Capture-MS
SUI1	YNL244C	Translation initiation factor eIF1	physical	1	1	1	Affinity Capture-MS
SNP1	YIL061C	Component of U1 snRNP required for mRNA splicing via spliceosome	physical	1	1	1	Affinity Capture-MS
RIO1	YOR119C	Serine kinase involved in cell cycle regulation and rDNA integrity	physical	1	1	1	Affinity Capture-MS
RRP5	YMR229C	RNA binding protein involved in synthesis of 18S and 5.8S rRNAs	genetic	1	1	1	Negative Genetic
HTA2	YBL003C	Histone H2A	physical	1	1	1	Affinity Capture-MS
SSA3	YBL075C	ATPase involved in protein folding and the response to stress	physical	1	1	1	Affinity Capture-MS
HMO1	YDR174W	Chromatin associated high mobility group (HMG) family member	physical	1	1	1	Affinity Capture-MS
SVF1	YDR346C	Protein with a potential role in cell survival pathways	physical	1	1	1	Affinity Capture-MS
POR1	YNL055C	Mitochondrial porin (voltage-dependent anion channel)	physical	1	1	1	Affinity Capture-MS
LYS9	YNR050C	Saccharopine dehydrogenase (NADP+, L-glutamate-forming)	physical	1	1	1	Affinity Capture-MS
RPS24B	YIL069C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS28B	YLR264W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
SNF2	YOR290C	Catalytic subunit of the SWI/SNF chromatin remodeling complex	physical	1	1	1	Affinity Capture-MS
YGR054W	YGR054W	Eukaryotic initiation factor eIF2A	physical	1	1	1	Affinity Capture-MS
KRI1	YNL308C	Essential nucleolar protein required for 40S ribosome biogenesis	genetic	1	1	1	Negative Genetic
MRD1	YPR112C	Essential conserved small ribosomal subunit (40s) synthesis factor	genetic	1	1	1	Negative Genetic
KSP1	YHR082C	Serine/threonine protein kinase	physical	1	1	1	Biochemical Activity
YCK2	YNL154C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	physical	1	1	1	Biochemical Activity
NOP15	YNL110C	Constituent of 66S pre-ribosomal particles	physical	1	1	1	Affinity Capture-MS
RCN1	YKL159C	Protein involved in calcineurin regulation during calcium signaling	physical	1	1	1	Two-hybrid
SSK22	YCR073C	MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway	physical	1	1	1	Affinity Capture-MS
GIS2	YNL255C	Translational activator for mRNAs with internal ribosome entry sites	physical	1	1	1	Affinity Capture-RNA
SPB4	YFL002C	Putative ATP-dependent RNA helicase	physical	1	1	1	Affinity Capture-MS
RPF2	YKR081C	Essential protein involved in rRNA maturation and ribosomal assembly	physical	1	1	1	Affinity Capture-MS
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	physical	1	1	1	Affinity Capture-RNA
MEX67	YPL169C	Poly(A)RNA binding protein involved in nuclear mRNA export	physical	1	1	1	Affinity Capture-Western
MTR2	YKL186C	mRNA transport regulator	physical	1	1	1	Affinity Capture-Western
ULP2	YIL031W	Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins	physical	1	1	1	Affinity Capture-MS
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	physical	1	1	1	Affinity Capture-MS
MYO1	YHR023W	Type II myosin heavy chain	physical	1	1	1	Affinity Capture-MS
HSP104	YLL026W	Disaggregase	physical	1	1	1	Affinity Capture-MS
RPC82	YPR190C	RNA polymerase III subunit C82	physical	1	1	1	Affinity Capture-MS
YBR138C	YBR138C	Cytoplasmic protein of unknown function	physical	1	1	1	Affinity Capture-MS
VTS1	YOR359W	Flap-structured DNA-binding and RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
PUF4	YGL014W	Member of the PUF protein family	physical	1	1	1	Affinity Capture-RNA
UTP5	YDR398W	Subunit of U3-containing Small Subunit (SSU) processome complex	genetic	1	1	1	Negative Genetic
UTP8	YGR128C	Nucleolar protein required for export of tRNAs from the nucleus	genetic	1	1	1	Negative Genetic
RPS0B	YLR048W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS0B	YLR048W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
RPS9A	YPL081W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS10B	YMR230W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS12	YOR369C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Synthetic Lethality
RPS15	YOL040C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
RPS16B	YDL083C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS19B	YNL302C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS21A	YKR057W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS21B	YJL136C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RET1	YOR207C	Second-largest subunit of RNA polymerase III	physical	1	1	1	Affinity Capture-MS
TFC6	YDR362C	Subunit of RNA polymerase III transcription initiation factor complex	physical	1	1	1	Affinity Capture-MS
RRP7	YCL031C	Essential protein involved in rRNA processing and ribosome biogenesis	physical	1	1	1	Affinity Capture-MS
RRP43	YCR035C	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
RPL2A	YFR031C-A	Ribosomal 60S subunit protein L2A	physical	1	1	1	Affinity Capture-MS
RPL8B	YLL045C	Ribosomal 60S subunit protein L8A	physical	1	1	1	Affinity Capture-MS
RPL15A	YLR029C	Ribosomal 60S subunit protein L15A	physical	1	1	1	Affinity Capture-MS
FCF2	YLR051C	Nucleolar protein involved in the early steps of 35S rRNA processing	physical	1	1	1	Affinity Capture-MS
FCF2	YLR051C	Nucleolar protein involved in the early steps of 35S rRNA processing	genetic	1	1	1	Negative Genetic
RPL22A	YLR061W	Ribosomal 60S subunit protein L22A	physical	1	1	1	Affinity Capture-MS
PWP1	YLR196W	Protein with WD-40 repeats involved in rRNA processing	physical	1	1	1	Affinity Capture-MS
UTP13	YLR222C	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
UTP13	YLR222C	Nucleolar protein	genetic	1	1	1	Negative Genetic
SGD1	YLR336C	Essential nuclear protein	physical	1	1	1	Affinity Capture-MS
RPP0	YLR340W	Conserved ribosomal protein P0 of the ribosomal stalk	physical	1	1	1	Affinity Capture-MS
RPL6B	YLR448W	Ribosomal 60S subunit protein L6B	physical	1	1	1	Affinity Capture-MS
MAK16	YAL025C	Essential nuclear protein	physical	1	1	1	Affinity Capture-MS
NOP6	YDL213C	rRNA-binding protein required for 40S ribosomal subunit biogenesis	physical	1	1	1	Affinity Capture-MS
RRP42	YDL111C	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
RPL4B	YDR012W	Ribosomal 60S subunit protein L4B	physical	1	1	1	Affinity Capture-MS
MAK21	YDR060W	Constituent of 66S pre-ribosomal particles	physical	1	1	1	Affinity Capture-MS
RRP45	YDR280W	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
FCF1	YDR339C	PINc domain endonuclease	genetic	1	1	1	Negative Genetic
ESF1	YDR365C	Nucleolar protein involved in pre-rRNA processing	physical	1	1	1	Affinity Capture-MS
RPL12B	YDR418W	Ribosomal 60S subunit protein L12B	physical	1	1	1	Affinity Capture-MS
PUF6	YDR496C	Pumilio-homology domain protein	physical	1	1	1	Affinity Capture-MS
RPL23A	YBL087C	Ribosomal 60S subunit protein L23A	physical	1	1	1	Affinity Capture-MS
MAK5	YBR142W	Essential nucleolar protein	physical	1	1	1	Affinity Capture-MS
XRN1	YGL173C	Evolutionarily-conserved 5'-3' exonuclease	physical	1	1	1	Affinity Capture-MS
RPL7A	YGL076C	Ribosomal 60S subunit protein L7A	physical	1	1	1	Affinity Capture-MS
RPS25A	YGR027C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPL26B	YGR034W	Ribosomal 60S subunit protein L26B	physical	1	1	1	Affinity Capture-MS
RRP46	YGR095C	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
ENP2	YGR145W	Component of the SSU	physical	1	1	1	Affinity Capture-MS
NSR1	YGR159C	Nucleolin, nucleolar protein that binds nuclear localization sequences	physical	1	1	1	Affinity Capture-MS
MTR4	YJL050W	RNA duplex-sensing translocase	physical	1	1	1	Affinity Capture-MS
URB2	YJR041C	Protein required for normal metabolism of the rRNA primary transcript	physical	1	1	1	Affinity Capture-MS
UTP11	YKL099C	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	1	1	1	Affinity Capture-MS
URB1	YKL014C	Protein required for the normal accumulation of 25S and 5.8S rRNAs	physical	1	1	1	Affinity Capture-MS
MRT4	YKL009W	Protein involved in mRNA turnover and ribosome assembly	physical	1	1	1	Affinity Capture-MS
UTP30	YKR060W	Subunit of U3-containing 90S preribosome complex	physical	1	1	1	Affinity Capture-MS
NOP8	YOL144W	Nucleolar protein required for 60S ribosomal subunit biogenesis	physical	1	1	1	Affinity Capture-MS
RRP40	YOL142W	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
NOP12	YOL041C	Nucleolar protein involved in pre-25S rRNA processing	physical	1	1	1	Affinity Capture-MS
RRP6	YOR001W	Nuclear exosome exonuclease component	genetic	1	1	1	Negative Genetic
RPL3	YOR063W	Ribosomal 60S subunit protein L3	physical	1	1	1	Affinity Capture-MS
NOC2	YOR206W	Protein involved in ribosome biogenesis	physical	1	1	1	Affinity Capture-MS
YTM1	YOR272W	Ribosomal assembly factor and 66S pre-ribosomal particle constituent	physical	1	1	1	Affinity Capture-MS
UTP25	YIL091C	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
ERB1	YMR049C	Constituent of 66S pre-ribosomal particles	physical	1	1	1	Affinity Capture-MS
RPL13B	YMR142C	Ribosomal 60S subunit protein L13B	physical	1	1	1	Affinity Capture-MS
RPL20A	YMR242C	Ribosomal 60S subunit protein L20A	physical	1	1	1	Affinity Capture-MS
POP1	YNL221C	Subunit of RNase MRP, nuclear RNase P and telomerase complexes	physical	1	1	1	Affinity Capture-MS
NOP2	YNL061W	rRNA m5C methyltransferase	physical	1	1	1	Affinity Capture-MS
RLP7	YNL002C	Nucleolar protein similar to large ribosomal subunit L7 proteins	physical	1	1	1	Affinity Capture-MS
RPL36B	YPL249C-A	Ribosomal 60S subunit protein L36B	physical	1	1	1	Affinity Capture-MS
RPL1A	YPL220W	Ribosomal 60S subunit protein L1A	physical	1	1	1	Affinity Capture-MS
RPL5	YPL131W	Ribosomal 60S subunit protein L5	physical	1	1	1	Affinity Capture-MS
NAN1	YPL126W	U3 snoRNP protein	physical	1	1	1	Affinity Capture-MS
NOG1	YPL093W	Putative GTPase	physical	1	1	1	Affinity Capture-MS
NOP4	YPL043W	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
RPS23B	YPR132W	Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RRP9	YPR137W	Protein involved in pre-rRNA processing	physical	1	1	1	Affinity Capture-MS
RPP1	YHR062C	Subunit of both RNase MRP and nuclear RNase P	physical	1	1	1	Affinity Capture-MS
RRP3	YHR065C	Protein involved in rRNA processing	physical	1	1	1	Affinity Capture-MS
SSF1	YHR066W	Constituent of 66S pre-ribosomal particles	physical	1	1	1	Affinity Capture-MS
RRP4	YHR069C	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
RPF1	YHR088W	Protein involved in assembly and export of the large ribosomal subunit	physical	1	1	1	Affinity Capture-MS
UTP9	YHR196W	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
SNU13	YEL026W	RNA binding protein	physical	1	1	1	Affinity Capture-MS
SNU13	YEL026W	RNA binding protein	genetic	1	1	1	Negative Genetic
LCP5	YER127W	Essential protein involved in maturation of 18S rRNA	physical	1	1	1	Affinity Capture-MS
SKI6	YGR195W	Exosome non-catalytic core component	physical	1	1	1	Affinity Capture-MS
HCA4	YJL033W	DEAD box RNA helicase	physical	1	1	1	Affinity Capture-MS
NMD3	YHR170W	Protein involved in nuclear export of the large ribosomal subunit	physical	1	1	1	Affinity Capture-MS
SQS1	YNL224C	Protein that stimulates the ATPase and helicase activities of Prp43p	physical	1	1	1	Two-hybrid
PXR1	YGR280C	Essential protein involved in rRNA and snoRNA maturation	physical	1	1	1	Two-hybrid
SIS1	YNL007C	Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p	physical	1	1	1	Affinity Capture-MS
SEC61	YLR378C	Conserved ER protein translocation channel	physical	1	1	1	Affinity Capture-MS
RPS27A	YKL156W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
NAP1	YKR048C	Histone chaperone and assembly chaperone for Rps6a/b	physical	1	1	1	Affinity Capture-Western
MTQ2	YDR140W	S-adenosylmethionine-dependent methyltransferase	physical	1	1	1	Affinity Capture-MS
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	1	1	1	Negative Genetic
NCS2	YNL119W	Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs	genetic	1	1	1	Negative Genetic
PET8	YNL003C	S-adenosylmethionine transporter of the mitochondrial inner membrane	genetic	1	1	1	Negative Genetic
FUM1	YPL262W	Fumarase	genetic	1	1	1	Negative Genetic
NEW1	YPL226W	Translation termination and ribosome biogenesis factor	genetic	1	1	1	Negative Genetic
TCO89	YPL180W	Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p)	genetic	1	1	1	Negative Genetic
MAD1	YGL086W	Coiled-coil protein involved in spindle-assembly checkpoint	genetic	1	1	1	Synthetic Lethality
RRP1	YDR087C	Essential evolutionarily conserved nucleolar protein	genetic	1	1	1	Positive Genetic
SRV2	YNL138W	CAP (cyclase-associated protein)	genetic	1	1	1	Positive Genetic
SEC20	YDR498C	Membrane glycoprotein v-SNARE	genetic	1	1	1	Positive Genetic
SRP102	YKL154W	Signal recognition particle (SRP) receptor beta subunit	genetic	1	1	1	Positive Genetic
GPN2	YOR262W	Putative GTPase with a specific role in RNA pol II and polIII biogenes	genetic	1	1	1	Positive Genetic
YJR084W	YJR084W	Protein that forms a complex with Thp3p	genetic	1	1	1	Positive Genetic
SIW14	YNL032W	Inositol phosphatase involved in inositol pyrophosphate metabolism	genetic	1	1	1	Positive Genetic
INO4	YOL108C	Transcription factor involved in phospholipid synthesis	genetic	1	1	1	Positive Genetic
VMA3	YEL027W	Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase	genetic	1	1	1	Positive Genetic
SFB3	YHR098C	Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat	genetic	1	1	1	Positive Genetic
YJL136W-A	YJL136W-A	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
YNL042W-B	YNL042W-B	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
SLA2	YNL243W	Adaptor protein that links actin to clathrin and endocytosis	genetic	1	1	1	Positive Genetic
RPN5	YDL147W	Subunit of the CSN and 26S proteasome lid complexes	genetic	1	1	1	Negative Genetic
PDC2	YDR081C	Transcription factor for thiamine-regulated genes	genetic	1	1	1	Negative Genetic
SUP35	YDR172W	Translation termination factor eRF3	genetic	1	1	1	Negative Genetic
NSE3	YDR288W	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
SPC110	YDR356W	Inner plaque spindle pole body (SPB) component	genetic	1	1	1	Negative Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	1	1	1	Negative Genetic
NUP85	YJR042W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
GSP1	YLR293C	Ran GTPase	genetic	1	1	1	Negative Genetic
IPL1	YPL209C	Aurora kinase of chromosomal passenger complex	genetic	1	1	1	Negative Genetic
TPI1	YDR050C	Triose phosphate isomerase, abundant glycolytic enzyme	genetic	1	1	1	Negative Genetic
SEC1	YDR164C	Sm-like protein involved in docking and fusion of exocytic vesicles	genetic	1	1	1	Negative Genetic
SEC26	YDR238C	Essential beta-coat protein of the COPI coatomer	genetic	1	1	1	Negative Genetic
NTF2	YER009W	Nuclear envelope protein	genetic	1	1	1	Negative Genetic
NUP145	YGL092W	Essential protein with distinct roles in two nuclear pore subcomplexes	genetic	1	1	1	Negative Genetic
SRM1	YGL097W	Nucleotide exchange factor for Gsp1p	genetic	1	1	1	Negative Genetic
NUP57	YGR119C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
MTR3	YGR158C	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
SPC42	YKL042W	Central plaque component of spindle pole body (SPB)	genetic	1	1	1	Negative Genetic
PRP16	YKR086W	DEAH-box RNA helicase	genetic	1	1	1	Negative Genetic
NIP7	YPL211W	Nucleolar protein required for 60S ribosome subunit biogenesis	genetic	1	1	1	Negative Genetic
SLM3	YDL033C	tRNA-specific 2-thiouridylase	genetic	1	1	1	Negative Genetic
VAM7	YGL212W	Vacuolar SNARE protein	genetic	1	1	1	Negative Genetic
VPS24	YKL041W	One of four subunits of the ESCRT-III complex	genetic	1	1	1	Negative Genetic
VPS27	YNR006W	Endosomal protein that forms a complex with Hse1p	genetic	1	1	1	Negative Genetic
PTH4	YOL114C	Protein similar to the human peptidyl-tRNA hydrolase gene ICT1	genetic	1	1	1	Negative Genetic
MNE1	YOR350C	Protein involved in splicing Group I aI5-beta intron from COX1 mRNA	genetic	1	1	1	Negative Genetic
LEA1	YPL213W	Component of U2 snRNP complex	genetic	1	1	1	Negative Genetic
YME1	YPR024W	Catalytic subunit of i-AAA protease complex	genetic	1	1	1	Negative Genetic
VPS4	YPR173C	AAA-ATPase involved in multivesicular body (MVB) protein sorting	genetic	1	1	1	Negative Genetic
HMRA1	YCR097W	Silenced copy of a1 at HMR	genetic	1	1	1	Negative Genetic
RAM1	YDL090C	Beta subunit of the CAAX farnesyltransferase (FTase)	genetic	1	1	1	Negative Genetic
YEL073C	YEL073C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RIM101	YHL027W	Cys2His2 zinc-finger transcriptional repressor	genetic	1	1	1	Negative Genetic
YHR218W	YHR218W	Helicase-like protein encoded within the telomeric Y' element	genetic	1	1	1	Negative Genetic
RRT14	YIL127C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YIL134C-A	YIL134C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RPL40A	YIL148W	Ubiquitin-ribosomal 60S subunit protein L40A fusion protein	genetic	1	1	1	Negative Genetic
IMA5	YJL216C	Alpha-glucosidase	genetic	1	1	1	Negative Genetic
NUP100	YKL068W	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
YKR005C	YKR005C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
HBS1	YKR084C	GTPase with similarity to translation release factors	genetic	1	1	1	Negative Genetic
YLR125W	YLR125W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
HRI1	YLR301W	Protein of unknown function that interacts with Sec72p and Hrr25p	genetic	1	1	1	Negative Genetic
YML003W	YML003W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YNL050C	YNL050C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
GEP3	YOR205C	Protein required for mitochondrial ribosome small subunit biogenesis	genetic	1	1	1	Negative Genetic
FDH1	YOR388C	NAD(+)-dependent formate dehydrogenase	genetic	1	1	1	Negative Genetic
YPL034W	YPL034W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YPL119C-A	YPL119C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
GLE2	YER107C	RNA export factor associated with the nuclear pore complex (NPC)	genetic	1	1	1	Synthetic Growth Defect
RPS31	YLR167W	Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin	genetic	1	1	1	Synthetic Growth Defect
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	1	1	1	Negative Genetic
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	1	1	1	Negative Genetic
NAB2	YGL122C	Nuclear polyadenylated RNA-binding protein	genetic	1	1	1	Phenotypic Suppression
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
CRM1	YGR218W	Nuclear export factor, exportin	physical	1	1	1	Affinity Capture-MS
CCT6	YDR188W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	1	1	1	Affinity Capture-MS
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
DIA2	YOR080W	Origin-binding F-box protein	physical	1	1	1	Affinity Capture-MS
DIA2	YOR080W	Origin-binding F-box protein	genetic	1	1	1	Negative Genetic
ELG1	YOR144C	Subunit of an alternative replication factor C complex	genetic	1	1	1	Synthetic Lethality
DEF1	YKL054C	RNAPII degradation factor	genetic	1	1	1	Negative Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	1	1	1	Negative Genetic
AFG3	YER017C	Mitochondrial inner membrane m-AAA protease component	physical	1	1	1	Affinity Capture-MS
ASK10	YGR097W	Regulator of the Fps1p glycerol channel	genetic	1	1	1	Positive Genetic
CDC27	YBL084C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
CEP3	YMR168C	Essential kinetochore protein	genetic	1	1	1	Negative Genetic
BRF1	YGR246C	TFIIIB B-related factor	physical	1	1	1	Affinity Capture-MS
ABF1	YKL112W	DNA binding protein with possible chromatin-reorganizing activity	genetic	1	1	1	Negative Genetic
DBP6	YNR038W	Essential protein involved in ribosome biogenesis	physical	1	1	1	Affinity Capture-MS
EFT1	YOR133W	Elongation factor 2 (EF-2), also encoded by EFT2	physical	1	1	1	Co-fractionation
BUD23	YCR047C	Ribosome biogenesis factor	physical	1	1	1	Affinity Capture-Western
BUL2	YML111W	Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex	physical	1	1	1	Affinity Capture-MS
BRL1	YHR036W	Essential nuclear envelope/ER integral membrane protein	genetic	1	1	1	Negative Genetic
ATG33	YLR356W	Mitochondrial mitophagy-specific protein	genetic	1	1	1	Positive Genetic
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	physical	1	1	1	Affinity Capture-MS
EFG1	YGR271C-A	Ribosome biogenesis factor required for maturation of 18S rRNA	physical	1	1	1	Affinity Capture-MS
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	1	1	1	Negative Genetic