SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
7 |
4 |
6 |
Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
6 |
5 |
6 |
Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue, Phenotypic Enhancement, Positive Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
5 |
4 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Positive Genetic, Positive Genetic |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Co-localization, PCA |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
3 |
2 |
3 |
Co-fractionation, Co-fractionation, Affinity Capture-Western |
PTR3 |
YFR029W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement |
STP1 |
YDR463W |
Transcription factor |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CAN1 |
YEL063C |
Plasma membrane arginine permease |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Enhancement |
ARG56 |
YER069W |
Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Dosage Rescue |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
VLD1 |
YIR014W |
Component of Dsc E3 ligase complex in vacuolar membranes |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
TED1 |
YIL039W |
GPI-glycan remodelase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
SPC2 |
YML055W |
Subunit of signal peptidase complex |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
LIP1 |
YMR298W |
Ceramide synthase subunit |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
PIS1 |
YPR113W |
Phosphatidylinositol synthase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
PMP3 |
YDR276C |
Small plasma membrane protein |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
SSY5 |
YJL156C |
Serine protease of SPS plasma membrane amino acid sensor system |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
BSC6 |
YOL137W |
Protein of unknown function with 8 putative transmembrane segments |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
FMP46 |
YKR049C |
Putative redox protein containing a thioredoxin fold |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
EFM6 |
YNL024C |
Putative S-adenosylmethionine-dependent lysine methyltransferase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HCM1 |
YCR065W |
Forkhead transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GZF3 |
YJL110C |
GATA zinc finger protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG4 |
YHR018C |
Argininosuccinate lyase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG1 |
YOL058W |
Arginosuccinate synthetase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BNA5 |
YLR231C |
Kynureninase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARG3 |
YJL088W |
Ornithine carbamoyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SLM4 |
YBR077C |
Subunit of the EGO/GSE complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Co-localization |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
physical |
1 |
1 |
1 |
PCA |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
physical |
1 |
1 |
1 |
PCA |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
PCA |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
PCA |
MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
PCA |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
physical |
1 |
1 |
1 |
Two-hybrid |
PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Co-purification |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Two-hybrid |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
URA3 |
YEL021W |
Orotidine-5'-phosphate (OMP) decarboxylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
LYP1 |
YNL268W |
Lysine permease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS1 |
YIR034C |
Saccharopine dehydrogenase (NAD+, L-lysine-forming) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS2 |
YBR115C |
Alpha aminoadipate reductase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS9 |
YNR050C |
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PUT4 |
YOR348C |
Proline permease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ORT1 |
YOR130C |
Ornithine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS12 |
YIL094C |
Homo-isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYS4 |
YDR234W |
Homoaconitase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRO2 |
YOR323C |
Gamma-glutamyl phosphate reductase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
THG1 |
YGR024C |
tRNAHis guanylyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEU2 |
YCL018W |
Beta-isopropylmalate dehydrogenase (IMDH) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YAT1 |
YAR035W |
Outer mitochondrial carnitine acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
POS5 |
YPL188W |
Mitochondrial NADH kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUC2 |
YIL162W |
Invertase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PRR2 |
YDL214C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGA1 |
YNL158W |
Essential component of GPI-mannosyltransferase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP32 |
YPL280W |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL2 |
YIL143C |
Component of RNA polymerase transcription factor TFIIH holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD2 |
YJL035C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP123 |
YER110C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARG8 |
YOL140W |
Acetylornithine aminotransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DYS1 |
YHR068W |
Deoxyhypusine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BNA2 |
YJR078W |
Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BAP2 |
YBR068C |
High-affinity leucine permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
AMD2 |
YDR242W |
Putative amidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ALP1 |
YNL270C |
Arginine transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARG7 |
YMR062C |
Mitochondrial ornithine acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |