Standard name Systematic name Name description Description
IFA38 YBR159W Microsomal beta-keto-reductase Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides
Visualize the interactome of IFA38
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.09 0.160 0.135
ER 0.91 0.865 0.817
Cell Periphery NaN 0.055 NaN
Cort. Patches NaN NaN 0.125

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
IFA38 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2166 (B-ketoacyl-CoA reductase (3-hydroxytetracosanoyl-CoA)), r_2162 (B-ketoacyl-CoA reductase ((S)-3-hydroxypalmitoyl-CoA)), r_2163 (B-ketoacyl-CoA reductase (3-hydroxyoctadecanoyl-CoA)), r_2167 (B-ketoacyl-CoA reductase ((S)-3-hydroxyhexacosanoyl-CoA)), r_2164 (B-ketoacyl-CoA reductase (3-hydroxyicosanoyl-CoA)), r_2161 (B-ketoacyl-CoA reductase ((S)-3-hydroxytetradecanoyl-CoA)), r_2165 (B-ketoacyl-CoA reductase (3-hydroxydocosanoyl-CoA))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 3 2 1 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 2 2 2 PCA, Affinity Capture-MS
STB5 YHR178W Transcription factor regulation 2 2 1 chromatin immunoprecipitation- exonuclease evidence, RNA-sequencing evidence
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 2 2 1 Two-hybrid, Affinity Capture-MS
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
GET2 YER083C Subunit of the GET complex genetic 2 1 1 Negative Genetic, Negative Genetic
DSL1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic genetic 2 1 1 Negative Genetic, Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 2 1 1 Negative Genetic, Negative Genetic
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 2 1 1 Dosage Lethality, Dosage Lethality
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating genetic 2 1 1 Negative Genetic, Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 1 Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 1 1 Positive Genetic, Positive Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT2 YER161C Protein involved in negative regulation of transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Affinity Capture-MS
EMP24 YGL200C Component of the p24 complex physical 1 1 1 PCA
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
AVT4 YNL101W Vacuolar transporter physical 1 1 1 PCA
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 PCA
FET3 YMR058W Ferro-O2-oxidoreductase physical 1 1 1 PCA
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 1 1 1 Affinity Capture-MS
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Synthetic Lethality
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 PCA
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase physical 1 1 1 PCA
CTR1 YPR124W High-affinity copper transporter of plasma membrane physical 1 1 1 PCA
CSC1 YLR241W Calcium permeable gated cation channel physical 1 1 1 PCA
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
GNP1 YDR508C Broad specificity amino acid permease physical 1 1 1 PCA
ADP1 YCR011C Putative ATP-dependent permease of the ABC transporter family physical 1 1 1 PCA
CPT1 YNL130C Cholinephosphotransferase physical 1 1 1 PCA
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Synthetic Lethality
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Growth Defect
EPS1 YIL005W ER protein with chaperone and co-chaperone activity physical 1 1 1 PCA
ERV41 YML067C Protein localized to COPII-coated vesicles physical 1 1 1 PCA
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 PCA
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 PCA
GAP1 YKR039W General amino acid permease physical 1 1 1 PCA
HIP1 YGR191W High-affinity histidine permease physical 1 1 1 PCA
CSG2 YBR036C Endoplasmic reticulum membrane protein physical 1 1 1 PCA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Rescue
ERG25 YGR060W C-4 methyl sterol oxidase physical 1 1 1 PCA
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
BSD2 YBR290W Heavy metal ion homeostasis protein physical 1 1 1 PCA
COS3 YML132W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
HMG1 YML075C HMG-CoA reductase physical 1 1 1 PCA
EMP70 YLR083C Protein with a role in cellular adhesion and filamentous growth physical 1 1 1 PCA
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter physical 1 1 1 PCA
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase physical 1 1 1 PCA
CAN1 YEL063C Plasma membrane arginine permease physical 1 1 1 PCA
BAP3 YDR046C Amino acid permease physical 1 1 1 PCA
FUN26 YAL022C High affinity, broad selectivity, nucleoside/nucleobase transporter physical 1 1 1 PCA
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI physical 1 1 1 PCA
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
YEL1 YBL060W Guanine nucleotide exchange factor specific for Arf3p physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
MTC1 YJL123C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
KIN4 YOR233W Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane physical 1 1 1 Affinity Capture-Western
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
TSC13 YDL015C Enoyl reductase physical 1 1 1 PCA
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Synthetic Growth Defect
UIP3 YAR027W Putative integral membrane protein of unknown function physical 1 1 1 PCA
YAR028W YAR028W Putative integral membrane protein physical 1 1 1 PCA
YRO2 YBR054W Protein with a putative role in response to acid stress physical 1 1 1 PCA
YPC1 YBR183W Alkaline ceramidase physical 1 1 1 PCA
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 PCA
VBA2 YBR293W Permease of basic amino acids in the vacuolar membrane physical 1 1 1 PCA
MAL31 YBR298C Maltose permease physical 1 1 1 PCA
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 PCA
MCH1 YDL054C Protein with similarity to mammalian monocarboxylate permeases physical 1 1 1 PCA
YDL206W YDL206W Putative protein of unknown function physical 1 1 1 PCA
UGA4 YDL210W GABA (gamma-aminobutyrate) permease physical 1 1 1 PCA
SUR2 YDR297W Sphinganine C4-hydroxylase physical 1 1 1 PCA
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p physical 1 1 1 PCA
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi physical 1 1 1 PCA
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
PMP2 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) physical 1 1 1 PCA
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 PCA
VPS73 YGL104C Mitochondrial protein physical 1 1 1 PCA
YIP1 YGR172C Integral membrane protein physical 1 1 1 PCA
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease physical 1 1 1 PCA
YHL042W YHL042W Endoplasmic reticulum protein physical 1 1 1 PCA
VMA16 YHR026W Subunit c'' of the vacuolar ATPase physical 1 1 1 PCA
NSG1 YHR133C Protein involved in regulation of sterol biosynthesis physical 1 1 1 PCA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
QDR1 YIL120W Multidrug transporter of the major facilitator superfamily physical 1 1 1 PCA
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) physical 1 1 1 PCA
VTH2 YJL222W Putative membrane glycoprotein physical 1 1 1 PCA
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 PCA
YJR015W YJR015W Putative protein of unknown function physical 1 1 1 PCA
LAC1 YKL008C Ceramide synthase component physical 1 1 1 PCA
MCD4 YKL165C Protein involved in GPI anchor synthesis physical 1 1 1 PCA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 PCA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
MMP1 YLL061W High-affinity S-methylmethionine permease physical 1 1 1 PCA
THI73 YLR004C Putative plasma membrane permease physical 1 1 1 PCA
SEC72 YLR292C Non-essential subunit of Sec63 complex physical 1 1 1 PCA
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 PCA
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
PRM1 YNL279W Pheromone-regulated multispanning membrane protein physical 1 1 1 PCA
PHO91 YNR013C Low-affinity vacuolar phosphate transporter physical 1 1 1 PCA
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family physical 1 1 1 PCA
YPL264C YPL264C Endoplasmic reticulum protein of unknown function physical 1 1 1 PCA
SAM3 YPL274W High-affinity S-adenosylmethionine permease physical 1 1 1 PCA
YPR003C YPR003C Putative sulfate permease physical 1 1 1 PCA
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
OPT2 YPR194C Oligopeptide transporter physical 1 1 1 PCA
SGE1 YPR198W Plasma membrane multidrug transporter physical 1 1 1 PCA
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p physical 1 1 1 PCA
AVT3 YKL146W Vacuolar transporter physical 1 1 1 PCA
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 1 1 1 PCA
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
CHS7 YHR142W Protein of unknown function physical 1 1 1 PCA
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Positive Genetic
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
ERG3 YLR056W C-5 sterol desaturase physical 1 1 1 PCA
ELO1 YJL196C Elongase I, medium-chain acyl elongase physical 1 1 1 PCA
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention physical 1 1 1 PCA
COS5 YJR161C Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
COS6 YGR295C Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
GEX2 YKR106W Proton:glutathione antiporter physical 1 1 1 PCA
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease physical 1 1 1 PCA
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance physical 1 1 1 PCA
HXT11 YOL156W Hexose transporter physical 1 1 1 PCA
HXT9 YJL219W Putative hexose transporter that is nearly identical to Hxt11p physical 1 1 1 PCA
ALG11 YNL048W Alpha-1,2-mannosyltransferase physical 1 1 1 PCA
GUP2 YPL189W Probable membrane protein physical 1 1 1 PCA
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex physical 1 1 1 PCA
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters physical 1 1 1 PCA
GAS4 YOL132W 1,3-beta-glucanosyltransferase physical 1 1 1 PCA