| SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
physical |
13 |
4 |
9 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
physical |
11 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| NTC20 |
YBR188C |
Member of the NineTeen Complex (NTC) |
genetic |
9 |
4 |
6 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
| CWC21 |
YDR482C |
Protein involved in RNA splicing by the spliceosome |
genetic |
8 |
4 |
6 |
Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
physical |
7 |
4 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
6 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SYF2 |
YGR129W |
Member of the NineTeen Complex (NTC) |
genetic |
6 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CEF1 |
YMR213W |
Essential splicing factor |
physical |
4 |
4 |
3 |
Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Co-purification |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
3 |
3 |
3 |
Dosage Rescue, Synthetic Growth Defect, Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
| ECM2 |
YBR065C |
Pre-mRNA splicing factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
physical |
3 |
2 |
2 |
Reconstituted Complex, Two-hybrid, Two-hybrid |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| CWC2 |
YDL209C |
Member of the NineTeen Complex (NTC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NTC20 |
YBR188C |
Member of the NineTeen Complex (NTC) |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| REX3 |
YLR107W |
RNA exonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRP3 |
YDR473C |
Splicing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| INO2 |
YDR123C |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC2 |
YDL209C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC21 |
YDR482C |
Protein involved in RNA splicing by the spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ELC1 |
YPL046C |
Elongin C, conserved among eukaryotes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SYF2 |
YGR129W |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SPP382 |
YLR424W |
Essential protein that forms a dimer with Ntr2p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
physical |
1 |
1 |
1 |
Two-hybrid |
| YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| POP8 |
YBL018C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR131C |
YDR131C |
F-box protein subunit of SCF ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS62 |
YGR141W |
Vacuolar protein sorting (VPS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT3 |
YKL175W |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR061C |
YNR061C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JHD1 |
YER051W |
JmjC domain family histone demethylase specific for H3-K36 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DPH1 |
YIL103W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
