Standard name Systematic name Name description Description
LSM2 YBL026W Lsm (Like Sm) protein Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
Visualize the interactome of LSM2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.617 0.757 0.532
Nucleus 0.078 0.065 0.078
Vac/Vac Memb 0.468 0.284 0.377
Mito NaN NaN 0.084

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 2210

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LSM2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM1 YJL124C Lsm (Like Sm) protein physical 17 4 13 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification
LSM8 YJR022W Lsm (Like Sm) protein physical 12 3 8 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Co-localization
LSM3 YLR438C-A Lsm (Like Sm) protein physical 11 5 10 Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, PCA, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 10 4 9 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 7 3 6 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein physical 7 3 6 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western
LSM4 YER112W Lsm (Like Sm) protein physical 7 4 5 Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, PCA, Affinity Capture-Western
LSM6 YDR378C Lsm (Like Sm) protein physical 7 3 5 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling physical 6 4 6 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 6 3 6 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA
LSM7 YNL147W Lsm (Like Sm) protein physical 6 3 6 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein genetic 3 3 3 Dosage Rescue, Negative Genetic, Synthetic Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 3 2 3 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 2 2 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Rescue
PRP31 YGR091W Splicing factor physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex physical 2 2 2 Two-hybrid, Affinity Capture-Western
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 2 2 2 Negative Genetic, Synthetic Lethality
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 2 1 2 PCA, PCA
MTR3 YGR158C Exosome non-catalytic core component physical 2 1 2 Two-hybrid, Two-hybrid
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP4 YPR178W Splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 2 1 1 Negative Genetic, Negative Genetic
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 2 1 1 Negative Genetic, Negative Genetic
PRP31 YGR091W Splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 1 Negative Genetic, Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 2 1 1 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 1 Negative Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 1 1 Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 2 1 1 Negative Genetic, Negative Genetic
LIN1 YHR156C Non-essential component of U5 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 2 1 1 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 2 1 1 Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 2 1 1 Negative Genetic, Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes regulation 1 1 1 northern blot evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex physical 1 1 1 Two-hybrid
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-Western
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Synthetic Rescue
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Two-hybrid
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
ABD1 YBR236C Methyltransferase genetic 1 1 1 Positive Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Affinity Capture-MS
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Two-hybrid
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM5 YER146W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Two-hybrid
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Two-hybrid
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex physical 1 1 1 Two-hybrid
NEO1 YIL048W Phospholipid translocase (flippase) physical 1 1 1 Two-hybrid
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) physical 1 1 1 Two-hybrid
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Two-hybrid
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery physical 1 1 1 Two-hybrid
RAD18 YCR066W E3 ubiquitin ligase physical 1 1 1 Two-hybrid
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) physical 1 1 1 Two-hybrid
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase physical 1 1 1 Two-hybrid
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Two-hybrid
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex physical 1 1 1 Two-hybrid
SEF1 YBL066C Putative transcription factor physical 1 1 1 Two-hybrid
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type physical 1 1 1 Two-hybrid
SOV1 YMR066W Mitochondrial protein of unknown function physical 1 1 1 Two-hybrid
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 Two-hybrid
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing physical 1 1 1 Two-hybrid
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine physical 1 1 1 Two-hybrid
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases physical 1 1 1 Two-hybrid
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network physical 1 1 1 Two-hybrid
YLR126C YLR126C Putative glutamine amidotransferase physical 1 1 1 Two-hybrid
YOL163W YOL163W Putative protein of unknown function physical 1 1 1 Two-hybrid
YPS1 YLR120C Aspartic protease physical 1 1 1 Two-hybrid
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Two-hybrid
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPL36B YPL249C-A Ribosomal 60S subunit protein L36B physical 1 1 1 Two-hybrid
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Co-purification
SMD1 YGR074W Core Sm protein Sm D1 physical 1 1 1 Affinity Capture-MS
PRP38 YGR075C Unique component of the U4/U6.U5 tri-snRNP particle physical 1 1 1 Affinity Capture-MS
PRP6 YBR055C Splicing factor physical 1 1 1 Affinity Capture-MS
PRP3 YDR473C Splicing factor physical 1 1 1 Affinity Capture-MS
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
RPB4 YJL140W RNA polymerase II subunit B32 physical 1 1 1 Two-hybrid
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 PCA
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 PCA
MFA2 YNL145W Mating pheromone a-factor physical 1 1 1 Protein-RNA
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Protein-RNA
RPL41A YDL184C Ribosomal 60S subunit protein L41A physical 1 1 1 Protein-RNA
RPB7 YDR404C RNA polymerase II subunit B16 physical 1 1 1 Two-hybrid
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-Western
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-Western
SMY2 YBR172C GYF domain protein physical 1 1 1 Affinity Capture-MS
SCD6 YPR129W Repressor of translation initiation physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay physical 1 1 1 Affinity Capture-MS
STL1 YDR536W Glycerol proton symporter of the plasma membrane physical 1 1 1 Affinity Capture-RNA
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Positive Genetic
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
URN1 YPR152C Protein of unknown function containing WW and FF domains genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
TKL2 YBR117C Transketolase genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YGR283C YGR283C Putative methyltransferase genetic 1 1 1 Negative Genetic
REC104 YHR157W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 1 1 1 Affinity Capture-MS
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Two-hybrid
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-RNA
FAR1 YJL157C CDK inhibitor and nuclear anchor physical 1 1 1 Two-hybrid
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
GDB1 YPR184W Glycogen debranching enzyme physical 1 1 1 Two-hybrid
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Two-hybrid
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Two-hybrid
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) physical 1 1 1 Two-hybrid
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
JLP1 YLL057C Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Positive Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Two-hybrid
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 1 1 1 Two-hybrid
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase physical 1 1 1 Two-hybrid
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
DCN1 YLR128W Scaffold-type E3 ligase physical 1 1 1 Two-hybrid
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) physical 1 1 1 Two-hybrid
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Positive Genetic
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Positive Genetic
CWC27 YPL064C Component of a complex containing Cef1p genetic 1 1 1 Negative Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
IRC20 YLR247C E3 ubiquitin ligase and putative helicase physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
BER1 YLR412W Protein involved in microtubule-related processes genetic 1 1 1 Negative Genetic
GAT3 YLR013W Protein containing GATA family zinc finger motifs genetic 1 1 1 Positive Genetic
ALG11 YNL048W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic