| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
physical |
26 |
8 |
19 |
Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-crystal Structure, Two-hybrid, Protein-peptide, Co-fractionation, Affinity Capture-Western, Two-hybrid, PCA, PCA, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, PCA, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
| PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
physical |
17 |
5 |
12 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western |
| PEX18 |
YHR160C |
Peroxin |
physical |
6 |
4 |
4 |
Two-hybrid, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-fractionation, Affinity Capture-Western |
| PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
physical |
5 |
3 |
4 |
Affinity Capture-Western, Co-purification, PCA, Affinity Capture-Western, Affinity Capture-Western |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
physical |
5 |
3 |
4 |
Two-hybrid, PCA, PCA, Protein-peptide, Two-hybrid |
| PEX11 |
YOL147C |
Peroxisomal protein required for medium-chain fatty acid oxidation |
physical |
4 |
3 |
4 |
PCA, PCA, Co-localization, Co-fractionation |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
physical |
4 |
2 |
4 |
Affinity Capture-Western, PCA, Affinity Capture-Western, PCA |
| PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| PEX7 |
YDR142C |
Peroxisomal signal receptor for peroxisomal matrix proteins |
physical |
4 |
3 |
3 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex |
| PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
physical |
4 |
4 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex |
| PEX21 |
YGR239C |
Peroxin required for peroxisomal matrix protein targeting |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
| PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
physical |
3 |
2 |
3 |
Affinity Capture-Western, PCA, Affinity Capture-Western |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX1 |
YKL197C |
AAA-peroxin |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX6 |
YNL329C |
AAA-peroxin |
physical |
2 |
2 |
2 |
Co-fractionation, Affinity Capture-Western |
| PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
physical |
2 |
2 |
2 |
Co-fractionation, PCA |
| PEX1 |
YKL197C |
AAA-peroxin |
physical |
2 |
2 |
2 |
Co-fractionation, Affinity Capture-Western |
| BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OYE3 |
YPL171C |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APL4 |
YPR029C |
Gamma-adaptin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
2 |
1 |
2 |
PCA, PCA |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AMD1 |
YML035C |
AMP deaminase |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| BNR1 |
YIL159W |
Formin |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Two-hybrid |
| APL1 |
YJR005W |
Beta-adaptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Two-hybrid |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP13 |
YGR084C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL83 |
YER027C |
One of three alternate beta-subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Two-hybrid |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIG2 |
YDR480W |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GND2 |
YGR256W |
6-phosphogluconate dehydrogenase (decarboxylating) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
physical |
1 |
1 |
1 |
PCA |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL7 |
YBR018C |
Galactose-1-phosphate uridyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN2 |
YLR096W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| CAF4 |
YKR036C |
WD40 repeat-containing protein associated with the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG20 |
YDL113C |
Sorting nexin family member |
physical |
1 |
1 |
1 |
PCA |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDT1 |
YBR187W |
Calcium and manganese transporter with higher affinity for Ca2+ |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMN1 |
YDR236C |
Riboflavin kinase, produces riboflavin monophosphate (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SGT1 |
YOR057W |
Cochaperone protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX6 |
YNL329C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| RRP7 |
YCL031C |
Essential protein involved in rRNA processing and ribosome biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| SAP1 |
YER047C |
Putative ATPase of the AAA family |
physical |
1 |
1 |
1 |
Two-hybrid |
| SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SOV1 |
YMR066W |
Mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
1 |
1 |
1 |
Two-hybrid |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Two-hybrid |
| YBP2 |
YGL060W |
Central kinetochore associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| YLL032C |
YLL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| RTT106 |
YNL206C |
Histone chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
physical |
1 |
1 |
1 |
Two-hybrid |
| SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
physical |
1 |
1 |
1 |
Two-hybrid |
| TPD3 |
YAL016W |
Regulatory subunit A of the heterotrimeric PP2A complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX3 |
YDR329C |
Peroxisomal membrane protein (PMP) |
physical |
1 |
1 |
1 |
PCA |
| PEX3 |
YDR329C |
Peroxisomal membrane protein (PMP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
PCA |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
physical |
1 |
1 |
1 |
PCA |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PEX35 |
YGR168C |
Regulator of peroxisome abundance |
physical |
1 |
1 |
1 |
PCA |
| SDS24 |
YBR214W |
Protein involved in cell separation during budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX1 |
YBR228W |
Endonuclease involved in DNA recombination and repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR10 |
YHR001W-A |
Subunit of the ubiqunol-cytochrome c oxidoreductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO4 |
YKR055W |
Non-essential small GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGD1 |
YLR336C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS62 |
YGR141W |
Vacuolar protein sorting (VPS) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TVP38 |
YKR088C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX22 |
YAL055W |
Putative peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RLI1 |
YDR091C |
Essential Fe-S protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYR1 |
YBR166C |
Prephenate dehydrogenase involved in tyrosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL186W |
YDL186W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YEF1 |
YEL041W |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL140C |
YGL140C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO74 |
YGL170C |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR273C |
YGR273C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPX1 |
YHR201C |
Exopolyphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR444W |
YDR444W |
Putative hydrolase acting on ester bonds |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR345W |
YLR345W |
Similar to 6-phosphofructo-2-kinase enzymes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR456W |
YLR456W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR272W-B |
YMR272W-B |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM15 |
YMR278W |
Phosphoribomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL190W |
YNL190W |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR064C |
YNR064C |
Epoxide hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL191C |
YPL191C |
K48-specific deubiquitinating (DUB) enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOT1 |
YMR172W |
Transcription factor for glycerol biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOS1 |
YPR068C |
Class I histone deacetylase (HDAC) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| NRG2 |
YBR066C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCL5 |
YHR071W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
physical |
1 |
1 |
1 |
Two-hybrid |
| ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE1 |
YAR015W |
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
physical |
1 |
1 |
1 |
Two-hybrid |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COI1 |
YDR381C-A |
Mitochondrial assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACB1 |
YGR037C |
Acyl-CoA-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AZR1 |
YGR224W |
Plasma membrane transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAG1 |
YHL003C |
Ceramide synthase component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPX2 |
YBR244W |
Phospholipid hydroperoxide glutathione peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS1 |
YNL336W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFM5 |
YGR001C |
S-adenosylmethionine-dependent lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL50 |
YNR022C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KNH1 |
YDL049C |
Protein with similarity to Kre9p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FDC1 |
YDR539W |
Ferulic acid decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAT1 |
YKL106W |
Mitochondrial aspartate aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |