Standard name Systematic name Name description Description
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain
Visualize the interactome of SRP54
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SRP54 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SEC65 YML105C Subunit of the signal recognition particle (SRP) physical 5 2 4 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 3 2 3 Dosage Rescue, Dosage Rescue, Negative Genetic
SRP21 YKL122C Subunit of the signal recognition particle (SRP) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SRP72 YPL210C Core component of the signal recognition particle (SRP) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Co-purification, Affinity Capture-MS
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 2 2 1 Co-fractionation, Affinity Capture-Western
SEC66 YBR171W Non-essential subunit of Sec63 complex physical 2 1 1 Reconstituted Complex, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Co-purification
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Co-purification
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex physical 1 1 1 Co-purification
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Co-purification
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component physical 1 1 1 Co-purification
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Co-purification
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Co-purification
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Co-purification
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 1 1 1 Co-purification
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
CTO1 YCR015C Protein required for cold tolerance physical 1 1 1 Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LCB2 YDR062W Component of serine palmitoyltransferase physical 1 1 1 Co-purification
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Co-purification
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Co-purification
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Co-purification
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) physical 1 1 1 Co-purification
MSL1 YIR009W U2B component of U2 snRNP physical 1 1 1 Co-purification
PRP42 YDR235W U1 snRNP protein involved in splicing physical 1 1 1 Co-purification
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 1 1 1 Affinity Capture-MS
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
YKL070W YKL070W Putative protein of unknown function physical 1 1 1 Co-purification
YJR027W YJR027W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Co-purification
YEL076C YEL076C Putative protein of unknown function physical 1 1 1 Co-purification
YHL049C YHL049C Putative protein of unknown function physical 1 1 1 Co-purification
YBL081W YBL081W Non-essential protein of unknown function physical 1 1 1 Co-purification
YBR225W YBR225W Putative protein of unknown function physical 1 1 1 Co-purification
YDR124W YDR124W Mitochondrial protein of unknown function physical 1 1 1 Co-purification
YER137C YER137C Protein of unknown function physical 1 1 1 Co-purification
YER187W YER187W Putative protein of unknown function physical 1 1 1 Co-purification
THI5 YFL058W Protein involved in synthesis of the thiamine precursor HMP physical 1 1 1 Co-purification
STR3 YGL184C Peroxisomal cystathionine beta-lyase physical 1 1 1 Co-purification
YHR210C YHR210C Putative aldose 1-epimerase superfamily protein physical 1 1 1 Co-purification
YML002W YML002W Putative protein of unknown function physical 1 1 1 Co-purification
YNL193W YNL193W Putative protein of unknown function physical 1 1 1 Co-purification
YPL113C YPL113C Glyoxylate reductase physical 1 1 1 Co-purification
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex physical 1 1 1 Co-purification
TKL2 YBR117C Transketolase physical 1 1 1 Co-purification
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome physical 1 1 1 Co-purification
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I physical 1 1 1 Co-purification
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes physical 1 1 1 Co-purification
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors physical 1 1 1 Co-purification
ZPR1 YGR211W Essential protein with two zinc fingers physical 1 1 1 Co-purification
TAD2 YJL035C Subunit of tRNA-specific adenosine-34 deaminase physical 1 1 1 Co-purification
ZAP1 YJL056C Zinc-regulated transcription factor physical 1 1 1 Co-purification
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Co-purification
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling physical 1 1 1 Co-purification
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Co-purification
YBL005W-A YBL005W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Co-purification
YGR109W-A YGR109W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Co-purification
TIM12 YBR091C Essential protein of the inner mitochondrial membrane physical 1 1 1 Co-purification
YMC2 YBR104W Putative mitochondrial inner membrane transporter physical 1 1 1 Co-purification
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Co-purification
TES1 YJR019C Peroxisomal acyl-CoA thioesterase physical 1 1 1 Co-purification
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Co-purification
YDR476C YDR476C Putative protein of unknown function physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Negative Genetic
THO1 YER063W Conserved nuclear RNA-binding protein genetic 1 1 1 Negative Genetic
YIL134C-A YIL134C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Negative Genetic
YML096W YML096W Putative protein with similarity to asparagine synthetases genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Co-purification
MNL1 YHR204W Alpha-1,2-specific exomannosidase of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Co-purification
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Dosage Rescue
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
NMD5 YJR132W Karyopherin physical 1 1 1 Co-purification
MGE1 YOR232W Mitochondrial matrix cochaperone physical 1 1 1 Co-purification
GSP2 YOR185C GTP binding protein (mammalian Ranp homolog) physical 1 1 1 Co-purification
GSP1 YLR293C Ran GTPase physical 1 1 1 Co-purification
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase physical 1 1 1 Co-purification
AGX1 YFL030W Alanine:glyoxylate aminotransferase (AGT) physical 1 1 1 Co-purification
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance physical 1 1 1 Co-purification
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis physical 1 1 1 Co-purification
MOH1 YBL049W Protein of unknown function, essential for stationary phase survival physical 1 1 1 Co-purification
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Two-hybrid
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Positive Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Affinity Capture-MS
GAL3 YDR009W Transcriptional regulator physical 1 1 1 Co-purification
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
GID10 YGR066C Recognition component (N-recognin) of the Pro/N-degron pathway physical 1 1 1 Co-purification
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase physical 1 1 1 Co-purification
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Co-purification
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Affinity Capture-MS
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 Two-hybrid
CDD1 YLR245C Cytidine deaminase genetic 1 1 1 Negative Genetic
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle physical 1 1 1 Co-purification
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase physical 1 1 1 Co-purification
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Co-purification
MSH5 YDL154W Protein of the MutS family physical 1 1 1 Co-purification
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit physical 1 1 1 Co-purification
CHA4 YLR098C DNA binding transcriptional activator physical 1 1 1 Co-purification
SHU1 YHL006C Component of Shu complex (aka PCSS complex) physical 1 1 1 Co-purification
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Co-purification
CEP3 YMR168C Essential kinetochore protein physical 1 1 1 Co-purification
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p physical 1 1 1 Co-purification
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SMC2 YFR031C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
RGT1 YKL038W Glucose-responsive transcription factor physical 1 1 1 Co-purification
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 1 1 1 Co-purification
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
RPA14 YDR156W RNA polymerase I subunit A14 physical 1 1 1 Co-purification
SEC20 YDR498C Membrane glycoprotein v-SNARE physical 1 1 1 Co-purification
SEC22 YLR268W R-SNARE protein physical 1 1 1 Reconstituted Complex
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding physical 1 1 1 Co-purification
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) physical 1 1 1 Co-purification
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
CMR2 YOR093C Putative protein of unknown function physical 1 1 1 Co-purification
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Co-purification
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Affinity Capture-MS
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Negative Genetic
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 1 1 1 Co-purification
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex physical 1 1 1 Co-purification
SHG1 YBR258C Subunit of the COMPASS (Set1C) complex physical 1 1 1 Co-purification
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Co-purification
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit physical 1 1 1 Co-purification
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 1 1 1 Co-purification
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Co-purification
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Co-purification
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
ERG5 YMR015C C-22 sterol desaturase physical 1 1 1 Co-purification
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis physical 1 1 1 Co-purification
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs genetic 1 1 1 Negative Genetic
ROG3 YFR022W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Co-purification
HUL4 YJR036C Protein with similarity to hect domain E3 ubiquitin-protein ligases physical 1 1 1 Co-purification
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
BPL1 YDL141W Biotin:apoprotein ligase physical 1 1 1 Co-purification
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
ICL1 YER065C Isocitrate lyase genetic 1 1 1 Negative Genetic
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein physical 1 1 1 Co-purification
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Co-purification
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Co-purification
PMU1 YKL128C Putative phosphomutase physical 1 1 1 Co-purification
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
PAD1 YDR538W Phenylacrylic acid decarboxylase physical 1 1 1 Co-purification
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
PGS1 YCL004W Phosphatidylglycerolphosphate synthase physical 1 1 1 Co-purification
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) physical 1 1 1 Co-purification
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Co-purification
SLM3 YDL033C tRNA-specific 2-thiouridylase physical 1 1 1 Co-purification
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MSN4 YKL062W Stress-responsive transcriptional activator physical 1 1 1 Co-purification
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 1 1 1 Co-purification
RDR1 YOR380W Transcriptional repressor involved in regulating multidrug resistance physical 1 1 1 Co-purification
DAP2 YHR028C Dipeptidyl aminopeptidase physical 1 1 1 Reconstituted Complex
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Negative Genetic
RGM1 YMR182C Putative zinc finger DNA binding transcription factor genetic 1 1 1 Negative Genetic
SGO1 YOR073W Component of the spindle checkpoint physical 1 1 1 Co-purification
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Co-purification
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth physical 1 1 1 Co-purification
ENA1 YDR040C P-type ATPase sodium pump genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Co-purification
BSC1 YDL037C Protein of unconfirmed function physical 1 1 1 Co-purification
MAL13 YGR288W MAL-activator protein physical 1 1 1 Co-purification
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Positive Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase physical 1 1 1 Co-purification
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
IML2 YJL082W Protein required for clearance of inclusion bodies genetic 1 1 1 Negative Genetic
MHO1 YJR008W Protein of unknown function physical 1 1 1 Co-purification
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity physical 1 1 1 Co-purification
GLO1 YML004C Monomeric glyoxalase I physical 1 1 1 Co-purification
DPL1 YDR294C Dihydrosphingosine phosphate lyase physical 1 1 1 Co-purification
LDO45 YMR147W Putative protein of unknown function physical 1 1 1 Co-purification
NAT4 YMR069W N alpha-acetyl-transferase physical 1 1 1 Co-purification
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit physical 1 1 1 Co-purification
LIH1 YJR107W Putative lipase physical 1 1 1 Co-purification
MXR2 YCL033C Methionine-R-sulfoxide reductase physical 1 1 1 Co-purification
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Positive Genetic
AIM32 YML050W 2Fe-2S mitochondrial protein involved in redox quality control physical 1 1 1 Co-purification
MAL33 YBR297W MAL-activator protein physical 1 1 1 Co-purification
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
JHD1 YER051W JmjC domain family histone demethylase specific for H3-K36 physical 1 1 1 Co-purification
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CTS2 YDR371W Putative chitinase genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing physical 1 1 1 Co-purification
SFM1 YOR021C SPOUT methyltransferase physical 1 1 1 Co-purification
BDS1 YOL164W Bacterially-derived sulfatase physical 1 1 1 Co-purification
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Positive Genetic
PPM1 YDR435C Carboxyl methyltransferase physical 1 1 1 Co-purification
SDH7 YDR511W Mitochondrial protein involved in assembly of succinate dehydrogenase physical 1 1 1 Co-purification
RRF1 YHR038W Mitochondrial ribosome recycling factor physical 1 1 1 Co-purification
ALP1 YNL270C Arginine transporter physical 1 1 1 Co-purification
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic