| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
5 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
4 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Suppression |
| DCR2 |
YLR361C |
Protein phosphatase |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Dosage Rescue |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GAP1 |
YKR039W |
General amino acid permease |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Suppression |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| PMT5 |
YDL093W |
Protein O-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| YBR096W |
YBR096W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YEA4 |
YEL004W |
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YSR3 |
YKR053C |
Dihydrosphingosine 1-phosphate phosphatase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| CTR2 |
YHR175W |
Low-affinity copper transporter of the vacuolar membrane |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SAY1 |
YGR263C |
Sterol deacetylase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNI1 |
YNL271C |
Formin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST1 |
YNL265C |
Protein with positive role in the multivesicular body sorting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRN1 |
YLR429W |
Coronin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELA1 |
YNL230C |
Elongin A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCH1 |
YNL281W |
Heat shock protein regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GTT1 |
YIR038C |
ER associated glutathione S-transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
| MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOR1 |
YNL274C |
Glyoxylate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPA43 |
YNL249C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGR2 |
YKL121W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Two-hybrid |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WWM1 |
YFL010C |
WW domain containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEX1 |
YNL253W |
Protein involved in mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL277W-A |
YNL277W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC2 |
YML055W |
Subunit of signal peptidase complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR16 |
YNL231C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
