NSA2 |
YER126C |
Protein constituent of 66S pre-ribosomal particles |
physical |
4 |
3 |
4 |
PCA, PCA, Two-hybrid, Affinity Capture-MS |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
3 |
2 |
3 |
Positive Genetic, Phenotypic Enhancement, Positive Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
3 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
2 |
2 |
2 |
PCA, Two-hybrid |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NOG2 |
YNR053C |
Putative GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MCX1 |
YBR227C |
Non-proteolytic ATPase of the AAA family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL37B |
YDR500C |
Ribosomal 60S subunit protein L37B |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPA1 |
YER049W |
Prolyl hydroxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PFS1 |
YHR185C |
Sporulation protein required for prospore membrane formation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SYG1 |
YIL047C |
Plasma membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSM7 |
YJR113C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LUG1 |
YLR352W |
Protein of unknown function with similarity to F-box proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MFA2 |
YNL145W |
Mating pheromone a-factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN1 |
YOL116W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL1 |
YJR005W |
Beta-adaptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP6 |
YBR120C |
Mitochondrial protein required for translation of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
APA1 |
YCL050C |
AP4A phosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSA2 |
YER126C |
Protein constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
physical |
1 |
1 |
1 |
PCA |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
LOC1 |
YFR001W |
Nucleolar protein involved in the asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Two-hybrid |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRZ1 |
YKR079C |
tRNA 3'-end processing endonuclease tRNase Z |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
LTV1 |
YKL143W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
STL1 |
YDR536W |
Glycerol proton symporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM2 |
YKR056W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR075C |
YKR075C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSA2 |
YKR077W |
Putative transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNU13 |
YEL026W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAD1 |
YDR538W |
Phenylacrylic acid decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRX20 |
YFR045W |
Putative mitochondrial transport protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUS6 |
YGR169C |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDP1 |
YIL113W |
Stress-inducible dual-specificity MAP kinase phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET5 |
YJR137C |
Sulfite reductase beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOL029C |
YOL029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOR072W-B |
YOR072W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RDR1 |
YOR380W |
Transcriptional repressor involved in regulating multidrug resistance |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Positive Genetic |
LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP25 |
YIL091C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
SQT1 |
YIR012W |
Specific assembly chaperone for ribosomal protein Rpl10p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC3 |
YLR066W |
Subunit of signal peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSR4 |
YOL022C |
Cytoplasmic assembly chaperone for ribosomal protein Rps2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC2 |
YBR147W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFR006W |
YFR006W |
Putative X-Pro aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCV1 |
YFR012W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH1 |
YHR120W |
DNA-binding protein of the mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA11 |
YHR159W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET130 |
YJL023C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAN1 |
YJR150C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUL1 |
YKL034W |
Subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOT13 |
YKL084W |
Zinc-binding mitochondrial intermembrane space (IMS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL107W |
YKL107W |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISA1 |
YLL027W |
Protein required for maturation of mitochondrial [4Fe-4S] proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL4 |
YLR439W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAI3 |
YMR174C |
Cytoplasmic proteinase A (Pep4p) inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR230W-A |
YMR230W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP41 |
YNL168C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNR021W |
YNR021W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAC1 |
YOR178C |
Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSP2 |
YOR242C |
Sporulation specific protein that localizes to the spore wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYH1 |
YPL105C |
Protein of unknown function that influences nuclear pore distribution |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPC25 |
YPL107W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Negative Genetic |