Standard name Systematic name Name description Description
ECM29 YHL030W Scaffold protein Scaffold protein; assists in association of proteasome core particle with regulatory particle; inhibitor of proteasome in vivo and in vitro; inhibits proteasomal ATPase activity; degraded by the mature proteasome after assembly; contains HEAT-like repeats; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress
Visualize the interactome of ECM29
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.685 0.557 0.591
Vac/Vac Memb 0.384 0.458 0.230
Cytoplasm NaN 0.078 0.088
Mito NaN NaN 0.197

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 2950

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ECM29 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 9 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 5 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 5 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 5 2 3 Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
UBP6 YFR010W Ubiquitin-specific protease physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 3 2 Phenotypic Suppression, Synthetic Rescue, Negative Genetic
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 3 3 2 Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 2 2 2 Co-purification, Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 2 2 2 Synthetic Rescue, Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 2 2 2 Synthetic Rescue, Negative Genetic
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LCB2 YDR062W Component of serine palmitoyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
YGL081W YGL081W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 2 Negative Genetic, Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 2 1 2 Negative Genetic, Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 2 1 2 Negative Genetic, Negative Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 2 2 1 Synthetic Lethality, Phenotypic Suppression
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
RPN14 YGL004C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 1 1 1 Affinity Capture-MS
RAD3 YER171W 5' to 3' DNA helicase physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase physical 1 1 1 Affinity Capture-MS
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 1 1 1 Synthetic Rescue
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
HRT1 YOL133W RING-H2 domain core subunit of multiple ubiquitin ligase complexes physical 1 1 1 Affinity Capture-MS
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MIR1 YJR077C Mitochondrial phosphate carrier physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 1 1 1 Affinity Capture-Western
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-Western
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
RPN14 YGL004C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 1 1 1 Affinity Capture-MS
PRE7 YBL041W Beta 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Affinity Capture-MS
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPL43A YPR043W Ribosomal 60S subunit protein L43A physical 1 1 1 Affinity Capture-MS
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Affinity Capture-MS
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
RPL36A YMR194W Ribosomal 60S subunit protein L36A physical 1 1 1 Affinity Capture-MS
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Affinity Capture-MS
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
HSP10 YOR020C Mitochondrial matrix co-chaperonin physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Affinity Capture-MS
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Affinity Capture-MS
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor physical 1 1 1 Affinity Capture-MS
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases physical 1 1 1 Affinity Capture-MS
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-MS
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Affinity Capture-MS
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
LYS2 YBR115C Alpha aminoadipate reductase physical 1 1 1 Affinity Capture-MS
RCN2 YOR220W Protein of unknown function physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
YPR1 YDR368W NADPH-dependent aldo-keto reductase genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
HUL5 YGL141W Multiubiquitin chain assembly factor (E4) genetic 1 1 1 Phenotypic Suppression
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator genetic 1 1 1 Synthetic Growth Defect
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-MS
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS