| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
2 |
2 |
Dosage Lethality, Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YKR075C |
YKR075C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| YOL163W |
YOL163W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YOL131W |
YOL131W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDR15 |
YDR406W |
Plasma membrane ATP binding cassette (ABC) transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOL4 |
YGR248W |
6-phosphogluconolactonase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YML037C |
YML037C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HOP1 |
YIL072W |
Meiosis-specific protein required for chromosome synapsis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FDH1 |
YOR388C |
NAD(+)-dependent formate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN14 |
YJR061W |
Protein required for N-glycan mannosylphosphorylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRR2 |
YDL214C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SHE2 |
YKL130C |
RNA-binding protein that binds specific mRNAs and interacts with She3p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TDA10 |
YGR205W |
ATP-binding protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RGD3 |
YHR182W |
GTPase activating protein (GAP) for Rho3p, involved in cell polarity g |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YMR196W |
YMR196W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL029C |
YOL029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUL1 |
YBR294W |
High affinity sulfate permease of the SulP anion transporter family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER079W |
YER079W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC3 |
YGL226W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL102C |
YIL102C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR105W |
YOR105W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR084W |
YMR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAI3 |
YMR174C |
Cytoplasmic proteinase A (Pep4p) inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HCS1 |
YKL017C |
Hexameric DNA polymerase alpha-associated DNA helicase A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| FMS1 |
YMR020W |
Polyamine oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP32 |
YPL280W |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICS3 |
YJL077C |
Protein with a role in copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
