SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
11 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
physical |
9 |
4 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Reconstituted Complex |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
physical |
6 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MSL5 |
YLR116W |
Component of commitment complex |
physical |
3 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-MS |
PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Reconstituted Complex |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
3 |
2 |
2 |
Reconstituted Complex, Far Western, Reconstituted Complex |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Lethality |
LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SMX2 |
YFL017W-A |
Core Sm protein Sm G |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SMX3 |
YPR182W |
Core Sm protein Sm F |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SMD3 |
YLR147C |
Core Sm protein Sm D3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
physical |
1 |
1 |
1 |
Co-purification |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Protein-peptide |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Protein-peptide |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Protein-peptide |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SME1 |
YOR159C |
Core Sm protein Sm E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YHR127W |
YHR127W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRR2 |
YDL214C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR096W |
YJR096W |
Xylose and arabinose reductase |
physical |
1 |
1 |
1 |
Protein-peptide |
TDA3 |
YHR009C |
Putative oxidoreductase involved in late endosome to Golgi transport |
physical |
1 |
1 |
1 |
Protein-peptide |
YCR016W |
YCR016W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Protein-peptide |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Protein-peptide |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Protein-peptide |
YIL060W |
YIL060W |
Mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
YHL042W |
YHL042W |
Endoplasmic reticulum protein |
physical |
1 |
1 |
1 |
Protein-peptide |
YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
physical |
1 |
1 |
1 |
Protein-peptide |
TKL1 |
YPR074C |
Transketolase |
physical |
1 |
1 |
1 |
Protein-peptide |
YPT11 |
YNL304W |
Rab GTPase |
physical |
1 |
1 |
1 |
Protein-peptide |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Protein-peptide |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Protein-peptide |
YGR111W |
YGR111W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Protein-peptide |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Protein-peptide |
RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
physical |
1 |
1 |
1 |
Protein-peptide |
YDL086W |
YDL086W |
Putative carboxymethylenebutenolidase |
physical |
1 |
1 |
1 |
Protein-peptide |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Protein-peptide |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
physical |
1 |
1 |
1 |
Protein-peptide |
SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Protein-peptide |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Protein-peptide |
THI80 |
YOR143C |
Thiamine pyrophosphokinase |
physical |
1 |
1 |
1 |
Protein-peptide |
YMR196W |
YMR196W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
YPR147C |
YPR147C |
Bifunctional triacylglycerol lipase and short chain ester hydrolase |
physical |
1 |
1 |
1 |
Protein-peptide |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Protein-peptide |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
1 |
1 |
1 |
Protein-peptide |
TGL3 |
YMR313C |
Bifunctional triacylglycerol lipase and LPE acyltransferase |
physical |
1 |
1 |
1 |
Protein-peptide |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Protein-peptide |
YJR149W |
YJR149W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
PXP2 |
YJR111C |
Peroxisomal matrix protein with naturally active promoter |
physical |
1 |
1 |
1 |
Protein-peptide |
TES1 |
YJR019C |
Peroxisomal acyl-CoA thioesterase |
physical |
1 |
1 |
1 |
Protein-peptide |
YIL108W |
YIL108W |
Putative metalloendopeptidase |
physical |
1 |
1 |
1 |
Protein-peptide |
SMN1 |
YHR202W |
Putative AMP hydrolase |
physical |
1 |
1 |
1 |
Protein-peptide |
YHR112C |
YHR112C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Protein-peptide |
STR3 |
YGL184C |
Peroxisomal cystathionine beta-lyase |
physical |
1 |
1 |
1 |
Protein-peptide |
YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
physical |
1 |
1 |
1 |
Protein-peptide |
PTP1 |
YDL230W |
Phosphotyrosine-specific protein phosphatase |
physical |
1 |
1 |
1 |
Protein-peptide |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Protein-RNA |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SWT21 |
YNL187W |
Protein involved in mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRN3 |
YKL125W |
Protein required for transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER085C |
YER085C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Protein-peptide |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
physical |
1 |
1 |
1 |
Protein-peptide |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Protein-peptide |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Protein-peptide |
EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
Protein-peptide |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Protein-peptide |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
physical |
1 |
1 |
1 |
Protein-peptide |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN2 |
YGL094C |
Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP38 |
YGR075C |
Unique component of the U4/U6.U5 tri-snRNP particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Protein-peptide |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
physical |
1 |
1 |
1 |
Protein-peptide |
LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
physical |
1 |
1 |
1 |
Protein-peptide |
GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
physical |
1 |
1 |
1 |
Protein-peptide |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
1 |
1 |
1 |
Protein-peptide |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
physical |
1 |
1 |
1 |
Protein-peptide |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Protein-peptide |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
1 |
1 |
1 |
Protein-peptide |
OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
physical |
1 |
1 |
1 |
Protein-peptide |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
physical |
1 |
1 |
1 |
Protein-peptide |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIP1 |
YMR092C |
Actin cortical patch component |
physical |
1 |
1 |
1 |
Protein-peptide |
DAS1 |
YJL149W |
Putative SCF ubiquitin ligase F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
physical |
1 |
1 |
1 |
Protein-peptide |
LYS1 |
YIR034C |
Saccharopine dehydrogenase (NAD+, L-lysine-forming) |
physical |
1 |
1 |
1 |
Protein-peptide |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
physical |
1 |
1 |
1 |
Protein-peptide |
BNA5 |
YLR231C |
Kynureninase |
physical |
1 |
1 |
1 |
Protein-peptide |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
physical |
1 |
1 |
1 |
Protein-peptide |
FMP40 |
YPL222W |
Mitochondrial AMPylator in the pseudokinase selenoprotein-O family |
physical |
1 |
1 |
1 |
Protein-peptide |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Protein-peptide |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
physical |
1 |
1 |
1 |
Protein-peptide |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Protein-peptide |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
physical |
1 |
1 |
1 |
Protein-peptide |
MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
physical |
1 |
1 |
1 |
Protein-peptide |
MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
physical |
1 |
1 |
1 |
Protein-peptide |
ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Protein-peptide |
MLS1 |
YNL117W |
Malate synthase, enzyme of the glyoxylate cycle |
physical |
1 |
1 |
1 |
Protein-peptide |
LYS21 |
YDL131W |
Homocitrate synthase isozyme |
physical |
1 |
1 |
1 |
Protein-peptide |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHR1 |
YOR386W |
DNA photolyase involved in photoreactivation |
physical |
1 |
1 |
1 |
Protein-peptide |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
physical |
1 |
1 |
1 |
Protein-peptide |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
physical |
1 |
1 |
1 |
Protein-peptide |
MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
physical |
1 |
1 |
1 |
Protein-peptide |
FRD1 |
YEL047C |
Soluble fumarate reductase |
physical |
1 |
1 |
1 |
Protein-peptide |
HFD1 |
YMR110C |
Dehydrogenase involved in ubiquinone and sphingolipid metabolism |
physical |
1 |
1 |
1 |
Protein-peptide |
ADE12 |
YNL220W |
Adenylosuccinate synthase |
physical |
1 |
1 |
1 |
Protein-peptide |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Protein-peptide |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Protein-peptide |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
physical |
1 |
1 |
1 |
Protein-peptide |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGL3 |
YML118W |
3'-5' exonuclease specific for poly-A RNAs |
physical |
1 |
1 |
1 |
Protein-peptide |
LOA1 |
YPR139C |
Lysophosphatidic acid acyltransferase |
physical |
1 |
1 |
1 |
Protein-peptide |
PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
physical |
1 |
1 |
1 |
Protein-peptide |
ERG24 |
YNL280C |
C-14 sterol reductase |
physical |
1 |
1 |
1 |
Protein-peptide |
PAN5 |
YHR063C |
2-dehydropantoate 2-reductase |
physical |
1 |
1 |
1 |
Protein-peptide |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX18 |
YBR056W |
Putative glycoside hydrolase of the mitochondrial intermembrane space |
physical |
1 |
1 |
1 |
Protein-peptide |
MET7 |
YOR241W |
Folylpolyglutamate synthetase |
physical |
1 |
1 |
1 |
Protein-peptide |
PAI3 |
YMR174C |
Cytoplasmic proteinase A (Pep4p) inhibitor |
physical |
1 |
1 |
1 |
Protein-peptide |
DOG2 |
YHR043C |
2-deoxyglucose-6-phosphate phosphatase |
physical |
1 |
1 |
1 |
Protein-peptide |
MAL32 |
YBR299W |
Maltase (alpha-D-glucosidase) |
physical |
1 |
1 |
1 |
Protein-peptide |
IMA1 |
YGR287C |
Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) |
physical |
1 |
1 |
1 |
Protein-peptide |
POF1 |
YCL047C |
Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) |
physical |
1 |
1 |
1 |
Protein-peptide |
ARR2 |
YPR200C |
Arsenate reductase required for arsenate resistance |
physical |
1 |
1 |
1 |
Protein-peptide |
PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |