GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
BOI1	YBL085W	Protein involved in polar growth, functionally redundant with Boi2p	genetic	11	4	10	Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
BEM1	YBR200W	Protein containing SH3-domains	physical	9	4	8	Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Two-hybrid, Protein-peptide, Two-hybrid
CDC24	YAL041W	Guanine nucleotide exchange factor (GEF) for Cdc42p	physical	6	3	5	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid
JNM1	YMR294W	Component of the yeast dynactin complex	genetic	6	3	4	Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC42	YLR229C	Small rho-like GTPase	physical	5	3	3	Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
DYN1	YKR054C	Cytoplasmic heavy chain dynein	genetic	5	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NIP100	YPL174C	Large subunit of the dynactin complex	genetic	5	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARP1	YHR129C	Actin-related protein of the dynactin complex	genetic	5	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LDB18	YLL049W	Component of the dynactin complex	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAC1	YOR269W	Regulator of dynein, involved in intracellular transport	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC1	YDR164C	Sm-like protein involved in docking and fusion of exocytic vesicles	physical	5	4	2	PCA, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Reconstituted Complex
EXO70	YJL085W	Subunit of the exocyst complex	genetic	4	3	3	Negative Genetic, Negative Genetic, Dosage Rescue, Phenotypic Suppression
PAC11	YDR488C	Dynein intermediate chain, microtubule motor protein	genetic	4	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
NUM1	YDR150W	Protein required for nuclear migration	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DYN3	YMR299C	Dynein light intermediate chain (LIC)	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EPO1	YMR124W	Protein involved in septin-ER tethering	physical	3	2	3	Two-hybrid, PCA, Two-hybrid
SEC15	YGL233W	Essential 113 kDa subunit of the exocyst complex	genetic	3	2	3	Negative Genetic, Negative Genetic, Dosage Rescue
RHO3	YIL118W	Non-essential small GTPase of the Rho/Rac family of Ras-like proteins	genetic	3	2	3	Dosage Rescue, Dosage Rescue, Phenotypic Suppression
DSE1	YER124C	Daughter cell-specific protein	physical	3	1	3	Two-hybrid, Two-hybrid, Two-hybrid
BIT2	YBR270C	Subunit of TORC2 membrane-associated complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MSB1	YOR188W	Protein of unknown function	physical	2	2	2	Two-hybrid, Affinity Capture-Western
NAM7	YMR080C	ATP-dependent RNA helicase of the SFI superfamily	physical	2	2	2	Two-hybrid, Affinity Capture-RNA
SEC1	YDR164C	Sm-like protein involved in docking and fusion of exocytic vesicles	genetic	2	2	2	Negative Genetic, Dosage Rescue
BUD6	YLR319C	Actin- and formin-interacting protein	physical	2	2	2	Two-hybrid, PCA
BOI2	YER114C	Protein involved in polar growth	physical	2	2	2	Two-hybrid, Reconstituted Complex
BMH1	YER177W	14-3-3 protein, major isoform	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
ZDS2	YML109W	Protein with a role in regulating Swe1p-dependent polarized growth	physical	2	1	2	Two-hybrid, Two-hybrid
MPT5	YGL178W	mRNA-binding protein of the PUF family	physical	2	1	2	Affinity Capture-RNA, Affinity Capture-RNA
RHO4	YKR055W	Non-essential small GTPase	genetic	2	1	2	Dosage Rescue, Dosage Rescue
ELM1	YKL048C	Serine/threonine protein kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
MPO1	YGL010W	Dioxygenase that catalyzes alpha-oxygenation of 2-hydroxy fatty acids	genetic	2	1	2	Negative Genetic, Negative Genetic
RCI50	YKL133C	Mitochondrial protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
SWI6	YLR182W	Transcription cofactor	genetic	2	1	2	Positive Genetic, Positive Genetic
DBP1	YPL119C	ATP-dependent RNA helicase of the DEAD-box protein family	genetic	2	1	2	Negative Genetic, Negative Genetic
CNA1	YLR433C	Calcineurin A	physical	2	2	1	Reconstituted Complex, Biochemical Activity
RHO3	YIL118W	Non-essential small GTPase of the Rho/Rac family of Ras-like proteins	physical	2	2	1	Reconstituted Complex, Affinity Capture-Western
BOI1	YBL085W	Protein involved in polar growth, functionally redundant with Boi2p	physical	2	2	1	PCA, Two-hybrid
STE20	YHL007C	Cdc42p-activated signal transducing kinase	physical	2	1	1	Two-hybrid, Two-hybrid
GLC7	YER133W	Type 1 S/T protein phosphatase (PP1) catalytic subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
RPP2B	YDR382W	Ribosomal protein P2 beta	genetic	2	1	1	Negative Genetic, Negative Genetic
UBA3	YPR066W	Protein that activates Rub1p (NEDD8) before neddylation	genetic	2	1	1	Negative Genetic, Negative Genetic
APC9	YLR102C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Positive Genetic, Positive Genetic
CBF1	YJR060W	Basic helix-loop-helix (bHLH) protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TYE7	YOR344C	Serine-rich protein that contains a bHLH DNA binding motif	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	regulation	1	1	1	quantitative mass spectrometry evidence
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	physical	1	1	1	Two-hybrid
MRS6	YOR370C	Rab escort protein	physical	1	1	1	Two-hybrid
MSB1	YOR188W	Protein of unknown function	genetic	1	1	1	Phenotypic Enhancement
SHO1	YER118C	Transmembrane osmosensor for filamentous growth and HOG pathways	physical	1	1	1	Two-hybrid
FIR1	YER032W	Protein involved in 3' mRNA processing	physical	1	1	1	Two-hybrid
IML1	YJR138W	GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex	physical	1	1	1	Two-hybrid
NIS1	YNL078W	Protein involved in axial bud site selection	physical	1	1	1	Two-hybrid
NDC80	YIL144W	Component of the kinetochore-associated Ndc80 complex	physical	1	1	1	Two-hybrid
YER158C	YER158C	Protein of unknown function	physical	1	1	1	Two-hybrid
YMR244W	YMR244W	Putative protein of unknown function	physical	1	1	1	Two-hybrid
CDC55	YGL190C	Regulatory subunit B of protein phosphatase 2A (PP2A)	physical	1	1	1	Two-hybrid
CDC55	YGL190C	Regulatory subunit B of protein phosphatase 2A (PP2A)	genetic	1	1	1	Negative Genetic
DIG1	YPL049C	MAP kinase-responsive inhibitor of the Ste12p transcription factor	physical	1	1	1	Two-hybrid
DIG2	YDR480W	MAP kinase-responsive inhibitor of the Ste12p transcription factor	physical	1	1	1	Two-hybrid
MET31	YPL038W	Zinc-finger DNA-binding transcription factor	physical	1	1	1	Two-hybrid
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	physical	1	1	1	Two-hybrid
FUS3	YBL016W	Mitogen-activated serine/threonine protein kinase involved in mating	physical	1	1	1	Affinity Capture-MS
NBP2	YDR162C	Protein involved in the HOG (high osmolarity glycerol) pathway	physical	1	1	1	Protein-peptide
NBP2	YDR162C	Protein involved in the HOG (high osmolarity glycerol) pathway	genetic	1	1	1	Negative Genetic
HHF1	YBR009C	Histone H4	physical	1	1	1	Affinity Capture-MS
HHF2	YNL030W	Histone H4	physical	1	1	1	Affinity Capture-MS
HHT1	YBR010W	Histone H3	physical	1	1	1	Affinity Capture-MS
HHT2	YNL031C	Histone H3	physical	1	1	1	Affinity Capture-MS
CMR1	YDL156W	Nuclear protein with role in transcription, protein quality control	physical	1	1	1	Affinity Capture-MS
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	physical	1	1	1	Biochemical Activity
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Dosage Lethality
SSB2	YNL209W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Co-purification
CRM1	YGR218W	Nuclear export factor, exportin	physical	1	1	1	Affinity Capture-MS
SPT16	YGL207W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	physical	1	1	1	Affinity Capture-MS
RPB3	YIL021W	RNA polymerase II third largest subunit B44	physical	1	1	1	Affinity Capture-MS
TMA46	YOR091W	Protein of unknown function that associates with translating ribosomes	physical	1	1	1	Affinity Capture-MS
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	physical	1	1	1	Affinity Capture-RNA
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	physical	1	1	1	Co-localization
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
VTS1	YOR359W	Flap-structured DNA-binding and RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
FKS1	YLR342W	Catalytic subunit of 1,3-beta-D-glucan synthase	physical	1	1	1	Two-hybrid
TPK1	YJL164C	cAMP-dependent protein kinase catalytic subunit	physical	1	1	1	Two-hybrid
CBK1	YNL161W	Serine/threonine protein kinase of the the RAM signaling network	physical	1	1	1	Two-hybrid
RGA2	YDR379W	GTPase-activating protein for polarity-establishment protein Cdc42p	physical	1	1	1	Two-hybrid
RSR1	YGR152C	Ras-type GTPase	physical	1	1	1	Two-hybrid
RSR1	YGR152C	Ras-type GTPase	genetic	1	1	1	Synthetic Growth Defect
SEC4	YFL005W	Rab family GTPase	physical	1	1	1	Two-hybrid
NBA1	YOL070C	Protein involved in axial bud site selection	physical	1	1	1	Two-hybrid
PAR32	YDL173W	Low complexity protein	physical	1	1	1	Two-hybrid
RAS1	YOR101W	GTPase involved in G-protein signaling in adenylate cyclase activation	physical	1	1	1	Two-hybrid
RHO4	YKR055W	Non-essential small GTPase	physical	1	1	1	Two-hybrid
EXO84	YBR102C	Exocyst subunit with dual roles in exocytosis and spliceosome assembly	physical	1	1	1	PCA
EXO84	YBR102C	Exocyst subunit with dual roles in exocytosis and spliceosome assembly	genetic	1	1	1	Negative Genetic
SEC3	YER008C	Subunit of the exocyst complex	physical	1	1	1	PCA
SEC5	YDR166C	Essential 107kDa subunit of the exocyst complex	physical	1	1	1	PCA
SEC6	YIL068C	Essential 88kDa subunit of the exocyst complex	physical	1	1	1	PCA
SEC8	YPR055W	Essential 121 kDa subunit of the exocyst complex	physical	1	1	1	PCA
SEC8	YPR055W	Essential 121 kDa subunit of the exocyst complex	genetic	1	1	1	Negative Genetic
SEC15	YGL233W	Essential 113 kDa subunit of the exocyst complex	physical	1	1	1	PCA
EXO70	YJL085W	Subunit of the exocyst complex	physical	1	1	1	PCA
CDC5	YMR001C	Polo-like kinase required for mitotic exit	physical	1	1	1	Proximity Label-MS
MSS4	YDR208W	Phosphatidylinositol-4-phosphate 5-kinase	genetic	1	1	1	Synthetic Lethality
YKU70	YMR284W	Subunit of the telomeric Ku complex (Yku70p-Yku80p)	genetic	1	1	1	Synthetic Growth Defect
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	1	1	1	Synthetic Growth Defect
RAM1	YDL090C	Beta subunit of the CAAX farnesyltransferase (FTase)	genetic	1	1	1	Negative Genetic
PTC1	YDL006W	Type 2C protein phosphatase (PP2C)	genetic	1	1	1	Negative Genetic
PTC2	YER089C	Type 2C protein phosphatase (PP2C)	genetic	1	1	1	Negative Genetic
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	genetic	1	1	1	Negative Genetic
PLC1	YPL268W	Phospholipase C	genetic	1	1	1	Negative Genetic
MOD5	YOR274W	Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase	genetic	1	1	1	Negative Genetic
DDI1	YER143W	Aspartic-type endopeptidase	genetic	1	1	1	Negative Genetic
NPL3	YDR432W	RNA-binding protein	genetic	1	1	1	Synthetic Rescue
VHT1	YGR065C	High-affinity plasma membrane H+-biotin (vitamin H) symporter	genetic	1	1	1	Negative Genetic
CCT8	YJL008C	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
SEC10	YLR166C	Essential 100kDa subunit of the exocyst complex	genetic	1	1	1	Negative Genetic
SEC2	YNL272C	Guanyl-nucleotide exchange factor for the small G-protein Sec4p	genetic	1	1	1	Negative Genetic
DRS2	YAL026C	Trans-golgi network aminophospholipid translocase (flippase)	genetic	1	1	1	Negative Genetic
NPL4	YBR170C	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	1	1	1	Negative Genetic
NNK1	YKL171W	Protein kinase	genetic	1	1	1	Negative Genetic
PSR1	YLL010C	Plasma membrane-associated protein phosphatase	genetic	1	1	1	Negative Genetic
RPL1B	YGL135W	Ribosomal 60S subunit protein L1B	genetic	1	1	1	Negative Genetic
YGR016W	YGR016W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
VPS62	YGR141W	Vacuolar protein sorting (VPS) protein	genetic	1	1	1	Negative Genetic
YLR159W	YLR159W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
ROM2	YLR371W	Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p	genetic	1	1	1	Negative Genetic
YML100W-A	YML100W-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
MME1	YMR166C	Transporter of the mitochondrial inner membrane that exports magnesium	genetic	1	1	1	Negative Genetic
YOR012W	YOR012W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
FIN1	YDR130C	Spindle pole body-related intermediate filament protein	genetic	1	1	1	Negative Genetic
YOR268C	YOR268C	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
SSO1	YPL232W	Plasma membrane t-SNARE	genetic	1	1	1	Dosage Rescue
DSE3	YOR264W	Daughter cell-specific protein, may help establish daughter fate	genetic	1	1	1	Positive Genetic
KRE5	YOR336W	Protein required for beta-1,6 glucan biosynthesis	genetic	1	1	1	Positive Genetic
TOP2	YNL088W	Topoisomerase II	genetic	1	1	1	Phenotypic Suppression
BUB2	YMR055C	Mitotic exit network regulator	genetic	1	1	1	Negative Genetic
RGA1	YOR127W	GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP)	genetic	1	1	1	Dosage Rescue
BNI1	YNL271C	Formin	physical	1	1	1	PCA
APP1	YNL094W	Phosphatidate phosphatase, converts phosphatidate to diacylglycerol	genetic	1	1	1	Negative Genetic
AFR1	YDR085C	Protein required for pheromone-induced projection (shmoo) formation	physical	1	1	1	Two-hybrid
AIM44	YPL158C	Regulator of Cdc42p and Rho1p	physical	1	1	1	Two-hybrid
ASI2	YNL159C	Subunit of the inner nuclear membrane Asi ubiquitin ligase complex	genetic	1	1	1	Negative Genetic
ALP1	YNL270C	Arginine transporter	genetic	1	1	1	Negative Genetic