Standard name Systematic name Name description Description
INP52 YNL106C Polyphosphatidylinositol phosphatase Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication
Visualize the interactome of INP52
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.173 0.102 0.204
Cort. Patches 0.498 0.227 0.261
Cytoplasm 0.113 0.289 0.210
ER 0.076 0.142 0.083
Endosome 0.073 NaN NaN
Golgi 0.053 NaN NaN
Mito 0.213 0.427 0.599
Peroxisome 0.196 0.076 0.057
SpindlePole 0.086 NaN 0.051

GFP localization & abundance

GFP localization GFP abundance
actin low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
INP52 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_3157 (PI 4-P phosphatase (1-16:1, 2-18:1), cytoplasm), r_3206 (PI 4,5-P2 phosphatase (1-18:0, 2-18:1), cytoplasm), r_3201 (PI 4,5-P2 phosphatase (1-16:1, 2-16:1), cytoplasm), r_3114 (PI 3-P phosphatase (1-18:0, 2-16:1), cell envelope), r_3152 (PI 4-P phosphatase (1-16:0, 2-16:1), cytoplasm), r_3196 (PI 4,5-P2 phosphatase (1-16:0, 2-18:1), cell envelope), r_3180 (PI 3,5-P2 phosphatase (1-16:0, 2-18:1), cell envelope), r_3158 (PI 4-P phosphatase (1-18:0, 2-18:1), cytoplasm), r_3207 (PI 4,5-P2 phosphatase (1-18:1, 2-18:1), cytoplasm), r_3202 (PI 4,5-P2 phosphatase (1-18:0, 2-16:1), cytoplasm), r_3115 (PI 3-P phosphatase (1-18:1, 2-16:1), cell envelope), r_3153 (PI 4-P phosphatase (1-16:1, 2-16:1), cytoplasm), r_3197 (PI 4,5-P2 phosphatase (1-16:1, 2-18:1), cell envelope), r_3179 (PI 3,5-P2 phosphatase (1-18:1, 2-16:1), cell envelope), r_3181 (PI 3,5-P2 phosphatase (1-16:1, 2-18:1), cell envelope), r_3159 (PI 4-P phosphatase (1-18:1, 2-18:1), cytoplasm), r_3176 (PI 3,5-P2 phosphatase (1-16:0, 2-16:1), cell envelope), r_3116 (PI 3-P phosphatase (1-16:0, 2-18:1), cell envelope), r_3154 (PI 4-P phosphatase (1-18:0, 2-16:1), cytoplasm), r_3203 (PI 4,5-P2 phosphatase (1-18:1, 2-16:1), cytoplasm), r_3198 (PI 4,5-P2 phosphatase (1-18:0, 2-18:1), cell envelope), r_3182 (PI 3,5-P2 phosphatase (1-18:0, 2-18:1), cell envelope), r_3177 (PI 3,5-P2 phosphatase (1-16:1, 2-16:1), cell envelope), r_3117 (PI 3-P phosphatase (1-16:1, 2-18:1), cell envelope), r_3155 (PI 4-P phosphatase (1-18:1, 2-16:1), cytoplasm), r_3204 (PI 4,5-P2 phosphatase (1-16:0, 2-18:1), cytoplasm), r_3199 (PI 4,5-P2 phosphatase (1-18:1, 2-18:1), cell envelope), r_3183 (PI 3,5-P2 phosphatase (1-18:1, 2-18:1), cell envelope), r_3112 (PI 3-P phosphatase (1-16:0, 2-16:1), cell envelope), r_3178 (PI 3,5-P2 phosphatase (1-18:0, 2-16:1), cell envelope), r_3118 (PI 3-P phosphatase (1-18:0, 2-18:1), cell envelope), r_3156 (PI 4-P phosphatase (1-16:0, 2-18:1), cytoplasm), r_3205 (PI 4,5-P2 phosphatase (1-16:1, 2-18:1), cytoplasm), r_3184 (PI 3,5-P2 phosphatase (1-16:0, 2-16:1), cytoplasm), r_3200 (PI 4,5-P2 phosphatase (1-16:0, 2-16:1), cytoplasm), r_3113 (PI 3-P phosphatase (1-16:1, 2-16:1), cell envelope), r_3119 (PI 3-P phosphatase (1-18:1, 2-18:1), cell envelope), r_3146 (PI 4-P phosphatase (1-18:0, 2-16:1), cell envelope), r_3185 (PI 3,5-P2 phosphatase (1-16:1, 2-16:1), cytoplasm), r_3191 (PI 3,5-P2 phosphatase (1-18:1, 2-18:1), cytoplasm), r_3125 (PI 3-P phosphatase (1-16:1, 2-18:1), cytoplasm), r_3120 (PI 3-P phosphatase (1-16:0, 2-16:1), cytoplasm), r_3147 (PI 4-P phosphatase (1-18:1, 2-16:1), cell envelope), r_3186 (PI 3,5-P2 phosphatase (1-18:0, 2-16:1), cytoplasm), r_3121 (PI 3-P phosphatase (1-16:1, 2-16:1), cytoplasm), r_3192 (PI 4,5-P2 phosphatase (1-16:0, 2-16:1), cell envelope), r_3124 (PI 3-P phosphatase (1-16:0, 2-18:1), cytoplasm), r_3126 (PI 3-P phosphatase (1-18:0, 2-18:1), cytoplasm), r_3148 (PI 4-P phosphatase (1-16:0, 2-18:1), cell envelope), r_3190 (PI 3,5-P2 phosphatase (1-18:0, 2-18:1), cytoplasm), r_3187 (PI 3,5-P2 phosphatase (1-18:1, 2-16:1), cytoplasm), r_3193 (PI 4,5-P2 phosphatase (1-16:1, 2-16:1), cell envelope), r_3127 (PI 3-P phosphatase (1-18:1, 2-18:1), cytoplasm), r_3149 (PI 4-P phosphatase (1-16:1, 2-18:1), cell envelope), r_3122 (PI 3-P phosphatase (1-18:0, 2-16:1), cytoplasm), r_3188 (PI 3,5-P2 phosphatase (1-16:0, 2-18:1), cytoplasm), r_3144 (PI 4-P phosphatase (1-16:0, 2-16:1), cell envelope), r_3194 (PI 4,5-P2 phosphatase (1-18:0, 2-16:1), cell envelope), r_3150 (PI 4-P phosphatase (1-18:0, 2-18:1), cell envelope), r_3123 (PI 3-P phosphatase (1-18:1, 2-16:1), cytoplasm), r_3189 (PI 3,5-P2 phosphatase (1-16:1, 2-18:1), cytoplasm), r_3145 (PI 4-P phosphatase (1-16:1, 2-16:1), cell envelope), r_3195 (PI 4,5-P2 phosphatase (1-18:1, 2-16:1), cell envelope), r_3151 (PI 4-P phosphatase (1-18:1, 2-18:1), cell envelope)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 12 5 12 Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Phenotypic Suppression, Synthetic Lethality
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 10 4 9 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
PIL1 YGR086C Eisosome core component genetic 8 3 7 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 5 4 4 Two-hybrid, Protein-peptide, Co-localization, Affinity Capture-Western, Protein-peptide
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 5 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 4 2 4 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein physical 3 3 3 Affinity Capture-MS, Two-hybrid, Reconstituted Complex
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 3 3 3 Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 2 3 Dosage Rescue, Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 3 3 1 Dosage Rescue, Dosage Growth Defect, Synthetic Lethality
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YMR1 YJR110W Phosphatidylinositol 3-phosphate (PI3P) phosphatase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 2 1 2 Negative Genetic, Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 2 1 2 Negative Genetic, Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 2 1 2 Negative Genetic, Negative Genetic
ATO3 YDR384C Plasma membrane protein, putative ammonium transporter genetic 2 1 2 Negative Genetic, Negative Genetic
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 2 2 1 Affinity Capture-Western, Two-hybrid
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Synthetic Growth Defect
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 1 1 1 Synthetic Growth Defect
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex physical 1 1 1 PCA
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Positive Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-Western
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Affinity Capture-MS
RNH202 YDR279W Ribonuclease H2 subunit physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
SAW1 YAL027W 5'- and 3'-flap DNA binding protein physical 1 1 1 Affinity Capture-MS
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase physical 1 1 1 Affinity Capture-MS
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 PCA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Dosage Rescue
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Synthetic Lethality
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Synthetic Growth Defect
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Phenotypic Enhancement
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Synthetic Growth Defect
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Synthetic Growth Defect
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Positive Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Synthetic Growth Defect
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Synthetic Rescue
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Dosage Rescue
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Dosage Rescue
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Dosage Rescue
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Dosage Rescue
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Dosage Rescue
ROY1 YMR258C GTPase inhibitor with similarity to F-box proteins genetic 1 1 1 Dosage Rescue
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Dosage Rescue
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Dosage Rescue
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Rescue
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
OPY1 YBR129C Protein of unknown function genetic 1 1 1 Synthetic Lethality
PEP12 YOR036W Target membrane receptor (t-SNARE) genetic 1 1 1 Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Positive Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Positive Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Positive Genetic
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase genetic 1 1 1 Positive Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Positive Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Positive Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
YBR287W YBR287W Protein of unknown function genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Dosage Growth Defect
RBD2 YPL246C Possible rhomboid protease genetic 1 1 1 Phenotypic Suppression
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Positive Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Lethality
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ADO1 YJR105W Adenosine kinase physical 1 1 1 Affinity Capture-MS
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Positive Genetic
CNA1 YLR433C Calcineurin A physical 1 1 1 Reconstituted Complex
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
DSS1 YMR287C 3'-5' exoribonuclease genetic 1 1 1 Positive Genetic
DMA1 YHR115C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Dosage Rescue
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Synthetic Lethality
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Synthetic Lethality
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 1 1 1 Affinity Capture-MS
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Dosage Rescue
HMRA1 YCR097W Silenced copy of a1 at HMR genetic 1 1 1 Dosage Rescue
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
EXP1 YDL121C A cargo receptor protein for Pma1p genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Dosage Rescue
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Positive Genetic
ICS2 YBR157C Protein of unknown function genetic 1 1 1 Positive Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
ASP1 YDR321W Cytosolic L-asparaginase, involved in asparagine catabolism genetic 1 1 1 Negative Genetic
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Dosage Rescue
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic