Standard name Systematic name Name description Description
NRG1 YDR043C Transcriptional repressor Transcriptional repressor; recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response; activated in stochastic pulses of nuclear localization in response to low glucose
Visualize the interactome of NRG1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.411 0.549 0.726
Endosome 0.175 NaN NaN
Mito 0.077 0.254 NaN
Nucleus 0.130 0.141 0.116
Vac/Vac Memb 0.301 0.211 0.075
Budneck NaN NaN 0.055

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 556

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NRG1 11 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 8 4 7 Synthetic Rescue, Phenotypic Enhancement, Negative Genetic, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Synthetic Rescue
SNF1 YDR477W AMP-activated S/T protein kinase genetic 4 1 4 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue
RIM9 YMR063W Plasma membrane protein of unknown function genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Rescue
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NRG2 YBR066C Transcriptional repressor genetic 3 1 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 3 1 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
CYC8 YBR112C General transcriptional co-repressor physical 3 2 2 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Rescue
ASF1 YJL115W Nucleosome assembly factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YPL150W YPL150W Protein kinase of unknown cellular role genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex regulation 3 3 1 chromatin immunoprecipitation-PCR evidence, electrophoretic mobility shift assay evidence, reverse transcription polymerase chain reaction evidence
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 2 2 2 Synthetic Rescue, Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PRR2 YDL214C Serine/threonine protein kinase genetic 2 2 2 Positive Genetic, Dosage Growth Defect
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
VPS25 YJR102C Component of the ESCRT-II complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 2 2 Negative Genetic, Synthetic Rescue
CIP1 YPL014W Cyclin-dependent kinase inhibitor genetic 2 1 2 Positive Genetic, Positive Genetic
LIN1 YHR156C Non-essential component of U5 snRNP genetic 2 1 2 Negative Genetic, Negative Genetic
ECM25 YJL201W Endocytic site protein required for stress-induced cell elongation genetic 2 1 2 Negative Genetic, Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 1 2 Negative Genetic, Negative Genetic
FUM1 YPL262W Fumarase genetic 2 1 2 Negative Genetic, Negative Genetic
HUA2 YOR284W Cytoplasmic protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 2 Negative Genetic, Negative Genetic
YDR444W YDR444W Putative hydrolase acting on ester bonds genetic 2 1 2 Negative Genetic, Negative Genetic
VHS2 YIL135C Regulator of septin dynamics genetic 2 1 2 Negative Genetic, Negative Genetic
POG1 YIL122W DNA-binding transcriptional activator genetic 2 1 2 Negative Genetic, Negative Genetic
YHC3 YJL059W Protein required for the ATP-dependent transport of arginine genetic 2 1 2 Negative Genetic, Negative Genetic
YCT1 YLL055W High-affinity cysteine-specific transporter genetic 2 1 2 Negative Genetic, Negative Genetic
SHH3 YMR118C Putative mitochondrial inner membrane protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 2 1 2 Negative Genetic, Negative Genetic
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall genetic 2 1 2 Positive Genetic, Positive Genetic
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 2 1 2 Positive Genetic, Positive Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 2 Positive Genetic, Positive Genetic
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter genetic 2 1 2 Negative Genetic, Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SNF8 YPL002C Component of the ESCRT-II complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
VPS36 YLR417W Component of the ESCRT-II complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 2 2 1 Dosage Rescue, Synthetic Rescue
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 2 1 1 Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 1 1 Negative Genetic, Negative Genetic
SUE1 YPR151C Protein required for degradation of unstable forms of cytochrome c genetic 2 1 1 Negative Genetic, Negative Genetic
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MNN1 YER001W Alpha-1,3-mannosyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YER010C YER010C Bifunctional HMG aldolase/oxaloacetate decarboxylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GNP1 YDR508C Broad specificity amino acid permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG4 YGL012W C-24(28) sterol reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
NCE103 YNL036W Carbonic anhydrase regulation 1 1 1 DNA to cDNA expression microarray evidence
PPM1 YDR435C Carboxyl methyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ALT2 YDR111C Catalytically inactive alanine transaminase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TIR1 YER011W Cell wall mannoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UTR2 YEL040W Chitin transglycosylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
VLD1 YIR014W Component of Dsc E3 ligase complex in vacuolar membranes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HEM13 YDR044W Coproporphyrinogen III oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SMB1 YER029C Core Sm protein Sm B regulation 1 1 1 DNA to cDNA expression microarray evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
FCY1 YPR062W Cytosine deaminase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ELO1 YJL196C Elongase I, medium-chain acyl elongase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HIS6 YIL020C Enzyme that catalyzes the fourth step in the histidine pathway regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC6 YJL194W Essential ATP-binding protein required for DNA replication regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FRE4 YNR060W Ferric reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAL7 YBR018C Galactose-1-phosphate uridyl transferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GSY1 YFR015C Glycogen synthase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling regulation 1 1 1 DNA to cDNA expression microarray evidence
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FTR1 YER145C High affinity iron permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LSM5 YER146W Lsm (Like Sm) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCP1 YKR066C Mitochondrial cytochrome-c peroxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ISU2 YOR226C Mitochondrial protein required for iron-sulfur protein synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AMN1 YBR158W Modulator of cell separation and mitotic exit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p regulation 1 1 1 DNA to cDNA expression microarray evidence
YBL029W YBL029W Non-essential protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor regulation 1 1 1 DNA to cDNA expression microarray evidence
AQR1 YNL065W Plasma membrane transporter of the major facilitator superfamily regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 chromatin immunoprecipitation-chip evidence
JID1 YPR061C Probable Hsp40p co-chaperone regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAT4 YIR013C Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAT3 YLR013W Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAT2 YMR136W Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NUR1 YDL089W Protein involved in regulation of mitotic exit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BOP2 YLR267W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IRC22 YEL001C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKG3 YLR187W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029C-A YBL029C-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCN2 YOR220W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
ICS2 YBR157C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
HOR7 YMR251W-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABM1 YJR108W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
HER1 YOR227W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TBS1 YBR150C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs regulation 1 1 1 DNA to cDNA expression microarray evidence
FAF1 YIL019W Protein required for pre-rRNA processing regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RUP1 YOR138C Protein that regulates ubiquitination of Rsp5p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YJL107C YJL107C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGR237C YGR237C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
RRT15 YLR162W-A Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YKL096C-B YKL096C-B Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TDA6 YPR157W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOL014W YOL014W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
FMP48 YGR052W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR012C YLR012C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YMR084W YMR084W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YMR085W YMR085W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SKS1 YPL026C Putative serine/threonine protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SHC1 YER096W Sporulation-specific activator of Chs3p (chitin synthase III) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MIG3 YER028C Transcriptional regulator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRG2 YBR066C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRG1 YDR043C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFL1 YOR140W Transcriptional repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP7 YOL028C Transcriptional repressor of nitric oxide oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP4 YKL109W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR8 YLR266C Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SMT3 YDR510W Ubiquitin-like protein of the SUMO family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Biochemical Activity
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Phenotypic Suppression
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Dosage Growth Defect
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 genetic 1 1 1 Negative Genetic
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Positive Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Positive Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Synthetic Rescue
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
KIN1 YDR122W S/T protein kinase genetic 1 1 1 Dosage Growth Defect
HTB1 YDR224C Histone H2B genetic 1 1 1 Positive Genetic
GSP2 YOR185C GTP binding protein (mammalian Ranp homolog) genetic 1 1 1 Negative Genetic
ENV7 YPL236C Vacuolar membrane protein kinase genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Positive Genetic
KDX1 YKL161C Protein kinase genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Positive Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ETP1 YHL010C Protein of unknown function required for growth on ethanol genetic 1 1 1 Phenotypic Suppression
KIN2 YLR096W S/T protein kinase genetic 1 1 1 Dosage Growth Defect
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Synthetic Rescue
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Phenotypic Enhancement
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Lethality
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Synthetic Rescue
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
DAP1 YPL170W Heme-binding protein genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Positive Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Positive Genetic
CHA4 YLR098C DNA binding transcriptional activator genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Positive Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-Western
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor physical 1 1 1 Affinity Capture-Western
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Affinity Capture-Western
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
STF1 YDL130W-A Protein involved in regulation of the mitochondrial F1F0-ATP synthase genetic 1 1 1 Negative Genetic
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g genetic 1 1 1 Negative Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Positive Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Positive Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL1A YPL220W Ribosomal 60S subunit protein L1A genetic 1 1 1 Negative Genetic
YPL199C YPL199C Protein involved in nonstop mRNA decay genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Positive Genetic
PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase genetic 1 1 1 Dosage Growth Defect
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Dosage Growth Defect
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Rescue
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Phenotypic Suppression
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
YOR292C YOR292C Putative protein of unknown function genetic 1 1 1 Positive Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RGI2 YIL057C Protein of unknown function genetic 1 1 1 Negative Genetic
YKL183C-A YKL183C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Positive Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Negative Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Phenotypic Enhancement
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase genetic 1 1 1 Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Positive Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase genetic 1 1 1 Negative Genetic
BOP3 YNL042W Protein of unknown function genetic 1 1 1 Positive Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Synthetic Rescue
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Positive Genetic
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Negative Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Positive Genetic
CYC1 YJR048W Cytochrome c, isoform 1 genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF genetic 1 1 1 Positive Genetic
FLC1 YPL221W Flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Positive Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Positive Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Phenotypic Enhancement
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
DPC25 YPL107W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
HXT14 YNL318C Protein with similarity to hexose transporter family members genetic 1 1 1 Negative Genetic
ENB1 YOL158C Ferric enterobactin transmembrane transporter genetic 1 1 1 Positive Genetic
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Negative Genetic
CUP1-1 YHR053C Metallothionein genetic 1 1 1 Phenotypic Enhancement
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic