| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
7 |
3 |
7 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
7 |
3 |
6 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
6 |
2 |
5 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
5 |
3 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
| PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
physical |
5 |
4 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, PCA |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SPA2 |
YLL021W |
Component of the polarisome |
physical |
4 |
3 |
3 |
PCA, PCA, Affinity Capture-Western, Two-hybrid |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
physical |
4 |
2 |
2 |
PCA, Reconstituted Complex, Reconstituted Complex, PCA |
| CHS2 |
YBR038W |
Chitin synthase II |
physical |
4 |
4 |
1 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
physical |
3 |
3 |
3 |
Two-hybrid, Co-localization, Affinity Capture-MS |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
3 |
2 |
3 |
Negative Genetic, Dosage Rescue, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| BUD32 |
YGR262C |
Protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
3 |
3 |
2 |
Co-localization, Two-hybrid, Affinity Capture-Western |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Dosage Rescue |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| FUS2 |
YMR232W |
Cell fusion regulator |
genetic |
3 |
2 |
2 |
Dosage Rescue, Phenotypic Enhancement, Dosage Rescue |
| MSB3 |
YNL293W |
Rab GTPase-activating protein |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Reconstituted Complex |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| BNI1 |
YNL271C |
Formin |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
2 |
2 |
2 |
Two-hybrid, PCA |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
physical |
2 |
2 |
2 |
Two-hybrid, Reconstituted Complex |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
physical |
2 |
1 |
2 |
PCA, PCA |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BNI1 |
YNL271C |
Formin |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Dosage Rescue |
| GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
2 |
2 |
1 |
Dosage Lethality, Synthetic Lethality |
| FUS1 |
YCL027W |
Membrane protein localized to the shmoo tip |
genetic |
2 |
2 |
1 |
Dosage Rescue, Phenotypic Enhancement |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| NBA1 |
YOL070C |
Protein involved in axial bud site selection |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD3 |
YLR147C |
Core Sm protein Sm D3 |
physical |
1 |
1 |
1 |
Two-hybrid |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATP22 |
YDR350C |
Specific translational activator for the mitochondrial ATP6 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
PCA |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| AIP5 |
YFR016C |
Protein that positively regulates actin assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
physical |
1 |
1 |
1 |
Two-hybrid |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Proximity Label-MS |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADH5 |
YBR145W |
Alcohol dehydrogenase isoenzyme V |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
physical |
1 |
1 |
1 |
Two-hybrid |
| DSE3 |
YOR264W |
Daughter cell-specific protein, may help establish daughter fate |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ZIP1 |
YDR285W |
Transverse filament protein of the synaptonemal complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Two-hybrid |
| SRL2 |
YLR082C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TRE1 |
YPL176C |
Transferrin receptor-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP11 |
YKR098C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS1 |
YCL027W |
Membrane protein localized to the shmoo tip |
physical |
1 |
1 |
1 |
Co-localization |
| CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MFA2 |
YNL145W |
Mating pheromone a-factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INH1 |
YDL181W |
Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
| HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SGO1 |
YOR073W |
Component of the spindle checkpoint |
physical |
1 |
1 |
1 |
Two-hybrid |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSF1 |
YOR271C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPI34 |
YOR114W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Negative Genetic |
