Standard name Systematic name Name description Description
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p Protein involved in polar growth, functionally redundant with Boi2p; required for fusion of secretory vesicles with plasma membrane at sites of polarized growth; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain; relocalizes from bud neck to cytoplasm upon DNA replication stress; BOI1 has a paralog, BOI2, that arose from the whole genome duplication
Visualize the interactome of BOI1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 39

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.112 0.126 0.156
Budsite 0.131 0.156 0.132
Cell Periphery 0.117 0.050 0.058
Cort. Patches 0.476 0.402 0.218
Cytoplasm 0.359 0.392 0.514
SpindlePole 0.136 0.080 0.119
ER NaN 0.075 NaN
Peroxisome NaN 0.050 NaN
Mito NaN NaN 0.066

GFP localization & abundance

GFP localization GFP abundance
bud neck, cytoplasm, cell periphery, bud 1040

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
BOI1 0 0 3 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BOI2 YER114C Protein involved in polar growth genetic 11 4 10 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
BEM1 YBR200W Protein containing SH3-domains physical 7 4 7 Two-hybrid, Affinity Capture-MS, PCA, Two-hybrid, Protein-peptide, PCA, PCA
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 5 4 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, PCA, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 4 2 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
BUD6 YLR319C Actin- and formin-interacting protein physical 4 2 2 PCA, PCA, PCA, Reconstituted Complex
EPO1 YMR124W Protein involved in septin-ER tethering physical 3 2 3 Two-hybrid, PCA, PCA
DSE1 YER124C Daughter cell-specific protein physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
CDC42 YLR229C Small rho-like GTPase physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
SEC3 YER008C Subunit of the exocyst complex physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 3 2 2 Two-hybrid, Two-hybrid, Biochemical Activity
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 2 2 2 Two-hybrid, PCA
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 2 2 2 Biochemical Activity, PCA
NBA1 YOL070C Protein involved in axial bud site selection physical 2 2 2 Two-hybrid, PCA
ABD1 YBR236C Methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
YER158C YER158C Protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
YJR056C YJR056C Protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
NIS1 YNL078W Protein involved in axial bud site selection physical 2 1 2 Two-hybrid, Two-hybrid
RHO4 YKR055W Non-essential small GTPase genetic 2 1 2 Dosage Rescue, Dosage Rescue
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 2 1 2 Negative Genetic, Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 1 2 Dosage Rescue, Dosage Rescue
ELM1 YKL048C Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 2 1 2 Negative Genetic, Negative Genetic
YLR152C YLR152C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 2 1 2 Negative Genetic, Negative Genetic
AFR1 YDR085C Protein required for pheromone-induced projection (shmoo) formation physical 2 1 2 Two-hybrid, Two-hybrid
BNI1 YNL271C Formin physical 2 2 1 PCA, Reconstituted Complex
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 2 2 1 PCA, Reconstituted Complex
BOI2 YER114C Protein involved in polar growth physical 2 2 1 PCA, Two-hybrid
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex physical 2 2 1 PCA, Reconstituted Complex
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex physical 2 2 1 PCA, Reconstituted Complex
EXO70 YJL085W Subunit of the exocyst complex genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
NUM1 YDR150W Protein required for nuclear migration genetic 2 1 1 Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Negative Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Two-hybrid
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Two-hybrid
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein physical 1 1 1 Affinity Capture-MS
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Dosage Rescue
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 1 1 1 Two-hybrid
COQ1 YBR003W Hexaprenyl pyrophosphate synthetase physical 1 1 1 Two-hybrid
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase physical 1 1 1 Two-hybrid
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism physical 1 1 1 Two-hybrid
FIR1 YER032W Protein involved in 3' mRNA processing physical 1 1 1 Two-hybrid
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex physical 1 1 1 Two-hybrid
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Two-hybrid
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Two-hybrid
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
PEX3 YDR329C Peroxisomal membrane protein (PMP) physical 1 1 1 Two-hybrid
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Two-hybrid
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Two-hybrid
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor physical 1 1 1 Two-hybrid
YDR239C YDR239C Protein of unknown function physical 1 1 1 Two-hybrid
MNN14 YJR061W Protein required for N-glycan mannosylphosphorylation physical 1 1 1 Two-hybrid
YMR244W YMR244W Putative protein of unknown function physical 1 1 1 Two-hybrid
YNL234W YNL234W Protein of unknown function with similarity to globins physical 1 1 1 Two-hybrid
TOS7 YOL019W Protein involved in secretion and cell wall organization physical 1 1 1 Two-hybrid
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Two-hybrid
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
HXT11 YOL156W Hexose transporter physical 1 1 1 Two-hybrid
MET31 YPL038W Zinc-finger DNA-binding transcription factor physical 1 1 1 Two-hybrid
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Two-hybrid
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Two-hybrid
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Two-hybrid
RIM11 YMR139W Protein kinase physical 1 1 1 Two-hybrid
RTT106 YNL206C Histone chaperone physical 1 1 1 Two-hybrid
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Two-hybrid
SRY1 YKL218C 3-hydroxyaspartate dehydratase physical 1 1 1 Two-hybrid
STD1 YOR047C Protein involved in control of glucose-regulated gene expression physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-MS
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme physical 1 1 1 Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 Protein-peptide
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
MSB1 YOR188W Protein of unknown function physical 1 1 1 Affinity Capture-Western
MSB1 YOR188W Protein of unknown function genetic 1 1 1 Phenotypic Enhancement
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Dosage Rescue
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 PCA
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 PCA
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 PCA
RSR1 YGR152C Ras-type GTPase physical 1 1 1 PCA
RSR1 YGR152C Ras-type GTPase genetic 1 1 1 Synthetic Growth Defect
SEC4 YFL005W Rab family GTPase physical 1 1 1 PCA
PAR32 YDL173W Low complexity protein physical 1 1 1 PCA
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation physical 1 1 1 PCA
RHO4 YKR055W Non-essential small GTPase physical 1 1 1 PCA
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 PCA
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex physical 1 1 1 PCA
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex physical 1 1 1 PCA
EXO70 YJL085W Subunit of the exocyst complex physical 1 1 1 PCA
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Positive Genetic
PTK1 YKL198C Putative serine/threonine protein kinase genetic 1 1 1 Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Phenotypic Enhancement
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Negative Genetic
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
GCG1 YER163C Gamma-glutamyl cyclotransferase genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
SNA3 YJL151C Protein involved in efficient MVB sorting of proteins to the vacuole genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
YDR262W YDR262W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
SPR6 YER115C Protein of unknown function genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase genetic 1 1 1 Negative Genetic
SSO1 YPL232W Plasma membrane t-SNARE genetic 1 1 1 Dosage Rescue
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Two-hybrid
AIM44 YPL158C Regulator of Cdc42p and Rho1p physical 1 1 1 Two-hybrid
AIM9 YER080W Protein of unknown function genetic 1 1 1 Negative Genetic