Standard name Systematic name Name description Description
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors; forms part of the tail domain of mediator
Visualize the interactome of GAL11
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.25 0.209 0.144
Nucleus 0.84 0.873 0.892
Mito NaN 0.164 0.183

GFP localization & abundance

GFP localization GFP abundance
nucleus 606

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GAL11 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 18 5 13 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, PCA, PCA, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex physical 15 3 13 Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 12 4 7 Affinity Capture-Western, Affinity Capture-Western, PCA, PCA, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex physical 9 3 7 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 8 3 8 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western
SRB4 YER022W Subunit of the RNA polymerase II mediator complex physical 8 3 8 Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 7 4 7 Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 7 3 7 Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
MED8 YBR193C Subunit of the RNA polymerase II mediator complex physical 5 3 5 Affinity Capture-Western, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS
MED2 YDL005C Subunit of the RNA polymerase II mediator complex physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, PCA
TFA1 YKL028W TFIIE large subunit physical 4 3 4 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, PCA
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex physical 4 3 4 Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
TFA2 YKR062W TFIIE small subunit physical 4 3 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, PCA
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 4 3 2 Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 3 3 Synthetic Lethality, Synthetic Rescue, Phenotypic Enhancement
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 3 3 3 Reconstituted Complex, Co-purification, Affinity Capture-Western
CDC73 YLR418C Component of the Paf1p complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, PCA
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, PCA
MED1 YPR070W Subunit of the RNA polymerase II mediator complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
NUT1 YGL151W Component of the RNA polymerase II mediator complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 3 3 2 Affinity Capture-MS, PCA, Reconstituted Complex
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 3 2 2 PCA, Affinity Capture-Western, Affinity Capture-Western
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Phenotypic Enhancement
MED6 YHR058C Subunit of the RNA polymerase II mediator complex physical 2 2 2 Co-purification, Affinity Capture-MS
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex physical 2 2 2 Affinity Capture-MS, PCA
MSN2 YMR037C Stress-responsive transcriptional activator physical 2 2 2 Reconstituted Complex, PCA
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 2 2 Dosage Lethality, Positive Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 2 2 2 Co-localization, Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 2 2 Dosage Rescue, Synthetic Lethality
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Positive Genetic, Dosage Rescue
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MED4 YOR174W Subunit of the RNA polymerase II mediator complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGE1 YPR198W Plasma membrane multidrug transporter genetic 2 1 2 Dosage Rescue, Dosage Rescue
MED2 YDL005C Subunit of the RNA polymerase II mediator complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 2 1 1 Dosage Rescue, Dosage Rescue
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SAG1 YJR004C Alpha-agglutinin of alpha-cells regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR193C-A YMR193C-A Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
BUD19 YJL188C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YKL177W YKL177W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
FRE1 YLR214W Ferric reductase and cupric reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
PTR2 YKR093W Integral membrane peptide transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase regulation 1 1 1 DNA to cDNA expression microarray evidence
YBR062C YBR062C Protein of unknown function that interacts with Msb2p regulation 1 1 1 DNA to cDNA expression microarray evidence
RPL35A YDL191W Ribosomal 60S subunit protein L35A regulation 1 1 1 DNA to cDNA expression microarray evidence
RPL41A YDL184C Ribosomal 60S subunit protein L41A regulation 1 1 1 DNA to cDNA expression microarray evidence
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B regulation 1 1 1 DNA to cDNA expression microarray evidence
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) regulation 1 1 1 DNA to cDNA expression microarray evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 PCA
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 PCA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Lethality
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p physical 1 1 1 PCA
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Positive Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing physical 1 1 1 Two-hybrid
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Rescue
MSN5 YDR335W Karyopherin physical 1 1 1 Affinity Capture-MS
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Synthetic Lethality
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-Western
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Growth Defect
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit physical 1 1 1 Affinity Capture-Western
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Reconstituted Complex
TAF2 YCR042C TFIID subunit (150 kDa) physical 1 1 1 Affinity Capture-Western
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Synthetic Growth Defect
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Rescue
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-Western
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 PCA
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 PCA
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 PCA
RPB9 YGL070C RNA polymerase II subunit B12.6 physical 1 1 1 PCA
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 PCA
TOA2 YKL058W TFIIA small subunit physical 1 1 1 PCA
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 PCA
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 PCA
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 PCA
TAF7 YMR227C TFIID subunit (67 kDa) physical 1 1 1 PCA
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 PCA
TAF13 YML098W TFIID subunit (19 kDa) physical 1 1 1 PCA
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH physical 1 1 1 PCA
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 1 1 1 PCA
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 PCA
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 PCA
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 PCA
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 PCA
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 PCA
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 PCA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-MS
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Affinity Capture-MS
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network physical 1 1 1 Affinity Capture-Western
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 1 1 1 Dosage Rescue
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-Western
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Co-localization
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 1 1 1 Phenotypic Suppression
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
INO2 YDR123C Transcription factor physical 1 1 1 Protein-peptide
MET4 YNL103W Leucine-zipper transcriptional activator physical 1 1 1 Protein-peptide
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Dosage Rescue
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Dosage Rescue
SIR3 YLR442C Silencing protein genetic 1 1 1 Dosage Rescue
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Dosage Rescue
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Phenotypic Enhancement
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Synthetic Lethality
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Lethality
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Lethality
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Synthetic Rescue
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Synthetic Rescue
RIF1 YBR275C Protein involved in control of DNA replication genetic 1 1 1 Synthetic Rescue
PHO80 YOL001W Cyclin genetic 1 1 1 Phenotypic Suppression
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Lethality
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
RAD7 YJR052W Nucleotide excision repair (NER) protein genetic 1 1 1 Synthetic Growth Defect
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Enhancement
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Synthetic Lethality
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Phenotypic Suppression
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Dosage Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic