Standard name Systematic name Name description Description
NNF1 YJR112W Essential component of the outer kinetochore MIND complex Essential component of the outer kinetochore MIND complex; joins kinetochore subunits contacting DNA to those contacting microtubules; required for kinetochore bi-orientation and accurate chromosome segregation; complex consists of Mtw1p, Nnf1p, Nsl1p and Dsn1p; homologous to metazoan CENP-H proteins
Visualize the interactome of NNF1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1 286

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.302 0.145 0.142
Nucleolus 0.492 0.508 0.263
Peroxisome 0.092 NaN NaN
SpindlePole 0.774 0.814 0.925

GFP localization & abundance

GFP localization GFP abundance
spindle pole 2070

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NNF1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 19 6 16 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 17 5 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 9 4 6 Two-hybrid, Reconstituted Complex, Reconstituted Complex, PCA, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 8 4 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
KAR3 YPR141C Minus-end-directed microtubule motor physical 7 3 4 Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, PCA, Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 4 3 3 Affinity Capture-Western, Two-hybrid, PCA, Two-hybrid
MTW1 YAL034W-A Essential component of the MIND kinetochore complex genetic 4 3 2 Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex physical 4 2 2 Two-hybrid, PCA, Two-hybrid, Two-hybrid
MIF2 YKL089W Centromeric CDEIII region binding protein physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 3 1 3 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
NNF1 YJR112W Essential component of the outer kinetochore MIND complex physical 3 3 2 PCA, Two-hybrid, Affinity Capture-MS
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 3 2 2 Reconstituted Complex, Two-hybrid, Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 3 2 2 Two-hybrid, PCA, Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
NUM1 YDR150W Protein required for nuclear migration physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
PAC1 YOR269W Regulator of dynein, involved in intracellular transport physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
YLR031W YLR031W Putative protein of unknown function physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
MCM21 YDR318W Component of the kinetochore sub-complex COMA physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
CNN1 YFR046C Kinetochore protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 2 1 2 Two-hybrid, Two-hybrid
CIK1 YMR198W Kinesin-associated protein physical 2 1 2 Two-hybrid, Two-hybrid
SMC4 YLR086W Subunit of the condensin complex physical 2 1 2 Two-hybrid, Two-hybrid
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 2 1 2 Two-hybrid, Two-hybrid
CSE4 YKL049C Centromeric histone H3-like protein physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 2 1 2 Two-hybrid, Two-hybrid
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 2 1 1 Negative Genetic, Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 2 1 1 Negative Genetic, Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 2 1 1 Negative Genetic, Negative Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 2 1 1 Negative Genetic, Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 2 1 1 Negative Genetic, Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 2 1 1 Two-hybrid, Two-hybrid
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
KEL2 YGR238C Protein that negatively regulates mitotic exit physical 2 1 1 Two-hybrid, Two-hybrid
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 1 Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 1 Negative Genetic, Negative Genetic
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 2 1 1 Two-hybrid, Two-hybrid
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER physical 2 1 1 Two-hybrid, Two-hybrid
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 1 Two-hybrid, Two-hybrid
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 2 1 1 Two-hybrid, Two-hybrid
SHE9 YDR393W Protein required for normal mitochondrial morphology physical 2 1 1 Two-hybrid, Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 2 1 1 Two-hybrid, Two-hybrid
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 2 1 1 Two-hybrid, Two-hybrid
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 2 1 1 Two-hybrid, Two-hybrid
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 1 Negative Genetic, Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 2 1 1 Negative Genetic, Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 2 1 1 Two-hybrid, Two-hybrid
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation physical 2 1 1 Two-hybrid, Two-hybrid
ATG38 YLR211C Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I physical 2 1 1 Two-hybrid, Two-hybrid
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 2 1 1 Two-hybrid, Two-hybrid
IRC15 YPL017C Microtubule associated protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHL4 YDR254W Outer kinetochore protein required for chromosome stability physical 1 1 1 Affinity Capture-MS
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 1 1 1 Negative Genetic
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Negative Genetic
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Two-hybrid
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Two-hybrid
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRP1 YDR347W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Reconstituted Complex
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit physical 1 1 1 Two-hybrid
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 1 1 1 Two-hybrid
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Two-hybrid
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 1 1 1 Negative Genetic
ETP1 YHL010C Protein of unknown function required for growth on ethanol physical 1 1 1 Two-hybrid
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Synthetic Lethality
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) physical 1 1 1 Affinity Capture-Western
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 1 1 1 Affinity Capture-Western
MCM10 YIL150C Essential chromatin-associated protein physical 1 1 1 Two-hybrid
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex physical 1 1 1 Affinity Capture-MS
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein physical 1 1 1 Affinity Capture-Western
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
SLK19 YOR195W Kinetochore-associated protein physical 1 1 1 Affinity Capture-Western
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family physical 1 1 1 Affinity Capture-Western
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 1 1 1 Two-hybrid
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 PCA
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 1 1 1 Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 1 1 1 Reconstituted Complex
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
YSW1 YBR148W Protein required for normal prospore membrane formation physical 1 1 1 Two-hybrid
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Two-hybrid
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Two-hybrid
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Two-hybrid
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 1 1 1 Two-hybrid
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Two-hybrid
SRL2 YLR082C Protein of unknown function physical 1 1 1 Two-hybrid
SMC5 YOL034W Subunit of the SMC5-SMC6 complex physical 1 1 1 Two-hybrid
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
SGO1 YOR073W Component of the spindle checkpoint physical 1 1 1 Two-hybrid
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
RUD3 YOR216C Golgi matrix protein physical 1 1 1 Two-hybrid
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Two-hybrid
SPP1 YPL138C Subunit of COMPASS (Set1C) physical 1 1 1 Two-hybrid
YPL216W YPL216W Putative protein of unknown function physical 1 1 1 Two-hybrid
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSD1 YDR293C Translational repressor genetic 1 1 1 Dosage Rescue
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Dosage Rescue
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Positive Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
PWP2 YCR057C Conserved 90S pre-ribosomal component genetic 1 1 1 Negative Genetic
SNU13 YEL026W RNA binding protein genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
TIM44 YIL022W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RMP1 YLR145W Subunit of RNase MRP genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Negative Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
YKL050C YKL050C Protein of unknown function genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
PFF1 YBR074W Multi-spanning vacuolar membrane protease genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Negative Genetic
PIG1 YLR273C Putative targeting subunit for type-1 protein phosphatase Glc7p genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 1 1 1 Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
SPO77 YLR341W Meiosis-specific protein of unknown function genetic 1 1 1 Negative Genetic
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) genetic 1 1 1 Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Affinity Capture-MS
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Affinity Capture-Western
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Two-hybrid
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
LRG1 YDL240W GTPase-activating protein (GAP) genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex physical 1 1 1 Two-hybrid
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
GTA1 YEL043W Protein of unknown function physical 1 1 1 Two-hybrid
CNN1 YFR046C Kinetochore protein physical 1 1 1 Affinity Capture-MS
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Two-hybrid
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Positive Genetic
MAM1 YER106W Monopolin genetic 1 1 1 Negative Genetic
ECM13 YBL043W Non-essential protein of unknown function physical 1 1 1 Two-hybrid
MFG1 YDL233W Regulator of filamentous growth physical 1 1 1 Two-hybrid
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family physical 1 1 1 Two-hybrid
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Negative Genetic
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic