Standard name Systematic name Name description Description
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p Regulatory subunit of type 1 protein phosphatase Glc7p; involved in negative regulation of glucose-repressible genes; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; REG1 has a paralog, REG2, that arose from the whole genome duplication
Visualize the interactome of REG1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.913 0.973 0.976

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 2560

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
REG1 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SNF1 YDR477W AMP-activated S/T protein kinase genetic 14 3 12 Synthetic Rescue, Phenotypic Suppression, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 13 3 12 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 13 4 11 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
BMH1 YER177W 14-3-3 protein, major isoform physical 9 4 7 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 6 5 5 Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Positive Genetic, Synthetic Growth Defect, Synthetic Rescue
BMH2 YDR099W 14-3-3 protein, minor isoform physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
REG2 YBR050C Regulatory subunit of the Glc7p type-1 protein phosphatase genetic 5 2 3 Dosage Rescue, Synthetic Growth Defect, Dosage Rescue, Dosage Rescue, Synthetic Growth Defect
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 4 3 4 Synthetic Rescue, Positive Genetic, Synthetic Rescue, Phenotypic Suppression
BMH1 YER177W 14-3-3 protein, major isoform genetic 3 3 2 Synthetic Lethality, Phenotypic Suppression, Dosage Rescue
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 3 2 2 Dosage Rescue, Phenotypic Suppression, Dosage Rescue
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 2 2 Dosage Rescue, Synthetic Rescue
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 2 2 2 Synthetic Rescue, Negative Genetic
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 2 2 2 Synthetic Rescue, Positive Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
GPA1 YHR005C Subunit of G protein involved in pheromone response physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 2 2 1 Two-hybrid, Affinity Capture-Western
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MIG1 YGL035C Transcription factor involved in glucose repression regulation 1 1 1 qualitative western immunoblotting evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Synthetic Rescue
PRP3 YDR473C Splicing factor genetic 1 1 1 Synthetic Rescue
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-Western
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Synthetic Lethality
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Synthetic Lethality
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Positive Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Positive Genetic
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Synthetic Rescue
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Synthetic Rescue
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Affinity Capture-MS
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Phenotypic Suppression
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Two-hybrid
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SOL1 YNR034W Protein with a possible role in tRNA export physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Phenotypic Suppression
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SPT2 YER161C Protein involved in negative regulation of transcription physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-Western
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Synthetic Rescue
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Synthetic Rescue
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Lethality
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Phenotypic Suppression
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Lethality
SNX4 YJL036W Sorting nexin genetic 1 1 1 Positive Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Positive Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Synthetic Lethality
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Synthetic Rescue
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Synthetic Rescue
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Synthetic Rescue
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Synthetic Rescue
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Phenotypic Suppression
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Rescue
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Synthetic Rescue
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Positive Genetic
ATG29 YPL166W Autophagy-specific protein genetic 1 1 1 Positive Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex genetic 1 1 1 Dosage Rescue
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Positive Genetic
INM1 YHR046C Inositol monophosphatase genetic 1 1 1 Positive Genetic
BUD32 YGR262C Protein kinase genetic 1 1 1 Dosage Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 genetic 1 1 1 Phenotypic Enhancement
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Synthetic Rescue
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Rescue
ATG4 YNL223W Conserved cysteine protease required for autophagy genetic 1 1 1 Positive Genetic
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Phenotypic Suppression
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Positive Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Positive Genetic
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
GLG2 YJL137C Glycogenin glucosyltransferase genetic 1 1 1 Phenotypic Suppression
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Positive Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Positive Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Synthetic Rescue
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway genetic 1 1 1 Positive Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Positive Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Synthetic Rescue
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Synthetic Growth Defect
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
HXK2 YGL253W Hexokinase isoenzyme 2 physical 1 1 1 Affinity Capture-Western
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 1 1 1 Biochemical Activity
FBP1 YLR377C Fructose-1,6-bisphosphatase physical 1 1 1 Affinity Capture-Western
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Phenotypic Suppression
NNK1 YKL171W Protein kinase genetic 1 1 1 Positive Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 genetic 1 1 1 Phenotypic Enhancement
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein genetic 1 1 1 Positive Genetic
JIP4 YDR475C Protein of unknown function genetic 1 1 1 Positive Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 PCA
GLG1 YKR058W Glycogenin glucosyltransferase genetic 1 1 1 Phenotypic Suppression
ADE12 YNL220W Adenylosuccinate synthase physical 1 1 1 Affinity Capture-MS
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
ISR1 YPR106W Predicted protein kinase genetic 1 1 1 Positive Genetic
GLC3 YEL011W Glycogen branching enzyme, involved in glycogen accumulation genetic 1 1 1 Phenotypic Suppression
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Positive Genetic
PEX35 YGR168C Regulator of peroxisome abundance genetic 1 1 1 Synthetic Growth Defect