Standard name Systematic name Name description Description
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity Serine kinase involved in cell cycle regulation and rDNA integrity; associated with late pre-40S particles via its conserved C-terminal domain; prevents premature use of pre-40S particles in translation; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; phosphorylates Rpa43p in anaphase to remove Pol I from rDNA
Visualize the interactome of RIO1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RIO1 4 1 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 5 3 2 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 2 2 2 Phenotypic Enhancement, Positive Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 2 2 2 Synthetic Rescue, Negative Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 2 2 2 Synthetic Rescue, Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 2 2 2 Biochemical Activity, Two-hybrid
PRP43 YGL120C RNA helicase in the DEAH-box family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CEP3 YMR168C Essential kinetochore protein genetic 2 1 2 Negative Genetic, Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
NOP53 YPL146C Nucleolar protein physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
RKM4 YDR257C Ribosomal lysine methyltransferase physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
TIF11 YMR260C Translation initiation factor eIF1A physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
RPA43 YOR340C RNA polymerase I subunit A43 physical 2 2 1 Affinity Capture-Western, Biochemical Activity
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex physical 2 2 1 Two-hybrid, Affinity Capture-Western
SKY1 YMR216C SR protein kinase (SRPK) physical 2 2 1 Two-hybrid, Affinity Capture-Western
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 2 2 1 Two-hybrid, Affinity Capture-Western
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity regulation 1 1 1 protein kinase assay evidence
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
PLB1 YMR008C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Positive Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA physical 1 1 1 Two-hybrid
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 Two-hybrid
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Synthetic Lethality
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Two-hybrid
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
PTA1 YAL043C Subunit of holo-CPF physical 1 1 1 Two-hybrid
IMD3 YLR432W Inosine monophosphate dehydrogenase physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Positive Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Two-hybrid
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP physical 1 1 1 Reconstituted Complex
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Positive Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase physical 1 1 1 Two-hybrid
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing genetic 1 1 1 Phenotypic Suppression
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Dosage Rescue
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Positive Genetic
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Two-hybrid
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 1 1 1 Two-hybrid
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Two-hybrid
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Two-hybrid
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex physical 1 1 1 Two-hybrid
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
HEF3 YNL014W Translational elongation factor EF-3 genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Positive Genetic
DAS1 YJL149W Putative SCF ubiquitin ligase F-box protein genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Positive Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
AFR1 YDR085C Protein required for pheromone-induced projection (shmoo) formation physical 1 1 1 Two-hybrid
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Two-hybrid
ELG1 YOR144C Subunit of an alternative replication factor C complex physical 1 1 1 Two-hybrid
FKH2 YNL068C Forkhead family transcription factor physical 1 1 1 Two-hybrid
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Positive Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Two-hybrid
NTA1 YJR062C Amidase physical 1 1 1 Two-hybrid
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex physical 1 1 1 Two-hybrid
ECM31 YBR176W Ketopantoate hydroxymethyltransferase physical 1 1 1 Reconstituted Complex
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Positive Genetic
MSB2 YGR014W Mucin family member involved in various signaling pathways physical 1 1 1 Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase physical 1 1 1 Two-hybrid
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins physical 1 1 1 Affinity Capture-MS
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Reconstituted Complex
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
IOC2 YLR095C Subunit of the Isw1b complex physical 1 1 1 Two-hybrid
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Two-hybrid
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Positive Genetic
HAP4 YKL109W Transcription factor physical 1 1 1 Two-hybrid
MST28 YAR033W Putative integral membrane protein, involved in vesicle formation physical 1 1 1 Two-hybrid
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs physical 1 1 1 Two-hybrid
HCH1 YNL281W Heat shock protein regulator physical 1 1 1 Two-hybrid
ALY1 YKR021W Alpha arrestin, substrate of calcineurin physical 1 1 1 Reconstituted Complex
NRT1 YOR071C High-affinity nicotinamide riboside transporter physical 1 1 1 Two-hybrid
REC114 YMR133W Protein involved in early stages of meiotic recombination physical 1 1 1 Two-hybrid
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Positive Genetic
OAF1 YAL051W Oleate-activated transcription factor physical 1 1 1 Two-hybrid
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 1 1 1 Two-hybrid
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
ASN2 YGR124W Asparagine synthetase physical 1 1 1 Two-hybrid
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport physical 1 1 1 Two-hybrid
GEF1 YJR040W Voltage-gated chloride channel physical 1 1 1 Two-hybrid
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Reconstituted Complex
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Reconstituted Complex
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase physical 1 1 1 Two-hybrid
YRO2 YBR054W Protein with a putative role in response to acid stress physical 1 1 1 Two-hybrid
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 1 1 1 Two-hybrid
TBS1 YBR150C Protein of unknown function physical 1 1 1 Two-hybrid
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity physical 1 1 1 Two-hybrid
UGX2 YDL169C Protein of unknown function physical 1 1 1 Two-hybrid
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Two-hybrid
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Two-hybrid
YEA6 YEL006W Mitochondrial NAD+ transporter physical 1 1 1 Two-hybrid
TRP2 YER090W Anthranilate synthase physical 1 1 1 Two-hybrid
YGL235W YGL235W Putative protein of unknown function physical 1 1 1 Two-hybrid
YGR027W-B YGR027W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Two-hybrid
YGR038C-B YGR038C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Two-hybrid
YGR067C YGR067C Putative protein of unknown function physical 1 1 1 Two-hybrid
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 Two-hybrid
YHL050C YHL050C Putative protein of unknown function physical 1 1 1 Two-hybrid
YHR214C-C YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Two-hybrid
YIL177C YIL177C Putative Y' element ATP-dependent helicase physical 1 1 1 Two-hybrid
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Two-hybrid
YKR011C YKR011C Protein of unknown function physical 1 1 1 Two-hybrid
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 1 1 1 Two-hybrid
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes physical 1 1 1 Two-hybrid
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Two-hybrid
YML133C YML133C Putative Y' element ATP-dependent helicase physical 1 1 1 Two-hybrid
YMR051C YMR051C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Two-hybrid
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Two-hybrid
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
TEX1 YNL253W Protein involved in mRNA export physical 1 1 1 Two-hybrid
VPS17 YOR132W Subunit of the membrane-associated retromer complex physical 1 1 1 Two-hybrid
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor physical 1 1 1 Two-hybrid
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA physical 1 1 1 Two-hybrid
YPL257W-B YPL257W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Two-hybrid
YRF1-7 YPL283C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Two-hybrid
YPR158W-A YPR158W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Two-hybrid
YPR204W YPR204W DNA helicase encoded within the telomeric Y' element physical 1 1 1 Two-hybrid
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system physical 1 1 1 Two-hybrid
YMR317W YMR317W Putative protein of unknown function physical 1 1 1 Two-hybrid
UBX5 YDR330W UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Two-hybrid
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes physical 1 1 1 Two-hybrid
SNZ3 YFL059W Pyridoxal-5'-phosphate synthase physical 1 1 1 Two-hybrid
YHR219W YHR219W Putative protein of unknown function with similarity to helicases physical 1 1 1 Two-hybrid
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Positive Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
TRI1 YMR233W Non-essential sumoylated protein of unknown function genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YGR050C YGR050C Protein of unknown function genetic 1 1 1 Negative Genetic
YIR043C YIR043C Blocked reading frame genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis genetic 1 1 1 Negative Genetic
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Positive Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Negative Genetic
BIO2 YGR286C Biotin synthase physical 1 1 1 Two-hybrid
DSF1 YEL070W Mannitol dehydrogenase physical 1 1 1 Two-hybrid
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function physical 1 1 1 Two-hybrid
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Negative Genetic
RGM1 YMR182C Putative zinc finger DNA binding transcription factor physical 1 1 1 Two-hybrid
PHO8 YDR481C Repressible vacuolar alkaline phosphatase physical 1 1 1 Two-hybrid
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease physical 1 1 1 Two-hybrid
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase physical 1 1 1 Two-hybrid
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase physical 1 1 1 Two-hybrid
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Positive Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
FMP33 YJL161W Putative protein of unknown function physical 1 1 1 Two-hybrid
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
ENB1 YOL158C Ferric enterobactin transmembrane transporter physical 1 1 1 Two-hybrid
MRS3 YJL133W Iron transporter, mediates Fe2+ transport across inner mito membrane genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase physical 1 1 1 Two-hybrid
PXP2 YJR111C Peroxisomal matrix protein with naturally active promoter physical 1 1 1 Two-hybrid
REX3 YLR107W RNA exonuclease genetic 1 1 1 Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis physical 1 1 1 Two-hybrid