| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
7 |
4 |
5 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Dosage Growth Defect, Synthetic Rescue, Negative Genetic |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
6 |
3 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Enhancement |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
5 |
4 |
3 |
Two-hybrid, Affinity Capture-MS, Two-hybrid, Protein-peptide, Reconstituted Complex |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
4 |
4 |
3 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
4 |
3 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
3 |
3 |
2 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression |
| YEN1 |
YER041W |
Holliday junction resolvase |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect |
| KAR9 |
YPL269W |
Spindle positioning factor |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, PCA |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression |
| RDH54 |
YBR073W |
DNA-dependent ATPase |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| TOP2 |
YNL088W |
Topoisomerase II |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| THO2 |
YNL139C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LSM2 |
YBL026W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MSH3 |
YCR092C |
Mismatch repair protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DMC1 |
YER179W |
Meiosis-specific recombinase required for double-strand break repair |
physical |
1 |
1 |
1 |
Two-hybrid |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| LIF1 |
YGL090W |
Component of the DNA ligase IV complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
1 |
1 |
1 |
Two-hybrid |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| BIK1 |
YCL029C |
Microtubule-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
physical |
1 |
1 |
1 |
Two-hybrid |
| ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSM1 |
YJL103C |
Putative zinc cluster protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Two-hybrid |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN3 |
YPR154W |
Negative regulator of actin nucleation-promoting factor activity |
physical |
1 |
1 |
1 |
Two-hybrid |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO80 |
YDR421W |
Zinc finger transcriptional activator of the Zn2Cys6 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
physical |
1 |
1 |
1 |
Two-hybrid |
| HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TUB3 |
YML124C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Two-hybrid |
| TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RIF2 |
YLR453C |
Protein that binds to the Rap1p C-terminus |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PCP1 |
YGR101W |
Mitochondrial serine protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAN1 |
YGL232W |
Putative tRNA acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YEN1 |
YER041W |
Holliday junction resolvase |
physical |
1 |
1 |
1 |
Two-hybrid |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRR1 |
YOR162C |
Zn2-Cys6 zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YAR066W |
YAR066W |
Putative GPI protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZIP2 |
YGL249W |
Meiosis-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
