ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
physical |
16 |
5 |
10 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Protein-peptide, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
ATG29 |
YPL166W |
Autophagy-specific protein |
physical |
15 |
5 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
13 |
3 |
11 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
ATG31 |
YDR022C |
Autophagy-specific protein required for autophagosome formation |
physical |
9 |
4 |
7 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
physical |
6 |
3 |
5 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
5 |
2 |
4 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western |
SNX4 |
YJL036W |
Sorting nexin |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Two-hybrid, Two-hybrid |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
physical |
3 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
3 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
3 |
1 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Two-hybrid, Two-hybrid |
UBX3 |
YDL091C |
Clathrin-coated vesicle component, regulator of endocytosis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SUE1 |
YPR151C |
Protein required for degradation of unstable forms of cytochrome c |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
3 |
2 |
1 |
PCA, Reconstituted Complex, Reconstituted Complex |
HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
PRP3 |
YDR473C |
Splicing factor |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
MRP4 |
YHL004W |
Mitochondrial ribosomal protein of the small subunit |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
LDB18 |
YLL049W |
Component of the dynactin complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
PET123 |
YOR158W |
Mitochondrial ribosomal protein of the small subunit |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
YPL077C |
YPL077C |
Putative protein of unknown function |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNL040W |
YNL040W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAS5 |
YOL030W |
1,3-beta-glucanosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ACS1 |
YAL054C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ADY3 |
YDL239C |
Protein required for spore wall formation |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AIM25 |
YJR100C |
Mitochondria protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
physical |
1 |
1 |
1 |
Two-hybrid |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
physical |
1 |
1 |
1 |
Two-hybrid |
MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
physical |
1 |
1 |
1 |
Two-hybrid |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
YBR197C |
YBR197C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THI11 |
YJR156C |
Protein involved in synthesis of the thiamine precursor HMP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNX3 |
YOR357C |
Sorting nexin for late-Golgi enzymes |
physical |
1 |
1 |
1 |
Two-hybrid |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Two-hybrid |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YKL050C |
YKL050C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC34 |
YKR037C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
physical |
1 |
1 |
1 |
Two-hybrid |
PET20 |
YPL159C |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
physical |
1 |
1 |
1 |
Two-hybrid |
RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
physical |
1 |
1 |
1 |
Two-hybrid |
HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Two-hybrid |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Two-hybrid |
CNL1 |
YDR357C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
PHO92 |
YDR374C |
Posttranscriptional regulator of phosphate and glucose metabolism |
physical |
1 |
1 |
1 |
Two-hybrid |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YIL092W |
YIL092W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
physical |
1 |
1 |
1 |
Two-hybrid |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YIL152W |
YIL152W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
physical |
1 |
1 |
1 |
Two-hybrid |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Two-hybrid |
UBX6 |
YJL048C |
UBX (ubiquitin regulatory X) domain-containing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
BIT61 |
YJL058C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MRX12 |
YJR003C |
Protein that associates with mitochondrial ribosome |
physical |
1 |
1 |
1 |
Two-hybrid |
RSM26 |
YJR101W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
1 |
1 |
1 |
Two-hybrid |
HYM1 |
YKL189W |
Component of the RAM signaling network |
physical |
1 |
1 |
1 |
Two-hybrid |
USB1 |
YLR132C |
Putative poly(U)-specific 3'-to-5' RNA exonuclease |
physical |
1 |
1 |
1 |
Two-hybrid |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
SPP382 |
YLR424W |
Essential protein that forms a dimer with Ntr2p |
physical |
1 |
1 |
1 |
Two-hybrid |
MRPL4 |
YLR439W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SEN15 |
YMR059W |
Subunit of the tRNA splicing endonuclease |
physical |
1 |
1 |
1 |
Two-hybrid |
CEF1 |
YMR213W |
Essential splicing factor |
physical |
1 |
1 |
1 |
Two-hybrid |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
ISU2 |
YOR226C |
Mitochondrial protein required for iron-sulfur protein synthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
physical |
1 |
1 |
1 |
Two-hybrid |
MRPL40 |
YPL173W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
PLC1 |
YPL268W |
Phospholipase C |
physical |
1 |
1 |
1 |
Two-hybrid |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COG1 |
YGL223C |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Two-hybrid |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
TMA17 |
YDL110C |
Regulatory gamma subunit of fatty acid synthase (FAS) |
physical |
1 |
1 |
1 |
Two-hybrid |
IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Two-hybrid |
VAB2 |
YEL005C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
physical |
1 |
1 |
1 |
Two-hybrid |
HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
CEP3 |
YMR168C |
Essential kinetochore protein |
physical |
1 |
1 |
1 |
Two-hybrid |
MRPS17 |
YMR188C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
physical |
1 |
1 |
1 |
Two-hybrid |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TVP23 |
YDR084C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN1 |
YDR122W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
physical |
1 |
1 |
1 |
Two-hybrid |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPM2 |
YOL141W |
AdoMet-dependent tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL33 |
YBR297W |
MAL-activator protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAP1 |
YNL023C |
Protein that binds to Fpr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCI1 |
YOR180C |
Peroxisomal protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
AFR1 |
YDR085C |
Protein required for pheromone-induced projection (shmoo) formation |
physical |
1 |
1 |
1 |
Two-hybrid |
ADE17 |
YMR120C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIR1 |
YIL079C |
Zinc knuckle protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG16 |
YMR159C |
Conserved protein involved in autophagy |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG16 |
YMR159C |
Conserved protein involved in autophagy |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
physical |
1 |
1 |
1 |
Two-hybrid |
ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |