Standard name Systematic name Name description Description
ESC1 YMR219W Protein involved in telomeric silencing Protein involved in telomeric silencing; required for quiescent cell telomere hypercluster localization at nuclear membrane vicinity; interacts with PAD4-domain of Sir4p
Visualize the interactome of ESC1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.242 NaN NaN
Mito 0.181 0.483 0.728
Nuc Periphery 0.537 0.531 0.304
Nucleolus 0.242 0.198 0.132
Nucleus 0.067 0.068 NaN
Vac/Vac Memb 0.195 0.169 0.082

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ESC1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 9 5 6 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Affinity Capture-MS
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 8 2 6 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Co-localization
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 2 2 2 Affinity Capture-MS, Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 2 2 2 Negative Genetic, Phenotypic Suppression
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 1 2 Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
YPL034W YPL034W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
BER1 YLR412W Protein involved in microtubule-related processes genetic 2 1 2 Negative Genetic, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 2 2 1 Affinity Capture-MS, Co-localization
NFI1 YOR156C SUMO E3 ligase genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
SWT1 YOR166C RNA endoribonuclease involved in perinuclear mRNP quality control genetic 2 2 1 Synthetic Lethality, Phenotypic Enhancement
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 2 1 1 Negative Genetic, Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis regulation 1 1 1 DNA to cDNA expression microarray evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 Affinity Capture-MS
BUD32 YGR262C Protein kinase genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Positive Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Two-hybrid
AMD1 YML035C AMP deaminase physical 1 1 1 Affinity Capture-MS
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 1 1 1 Reconstituted Complex
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Affinity Capture-MS
TAF2 YCR042C TFIID subunit (150 kDa) physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Two-hybrid
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Rescue
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
YPR137C-B YPR137C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
IRR1 YIL026C Subunit of the cohesin complex physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 1 1 1 Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MET6 YER091C Cobalamin-independent methionine synthase physical 1 1 1 Affinity Capture-MS
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Affinity Capture-MS
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Affinity Capture-MS
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
MIR1 YJR077C Mitochondrial phosphate carrier physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
GPM2 YDL021W Nonfunctional homolog of Gpm1p phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPL20B YOR312C Ribosomal 60S subunit protein L20B physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-Western
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Synthetic Rescue
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Positive Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins genetic 1 1 1 Phenotypic Suppression
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Positive Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
TYW3 YGL050W tRNA methyltransferase required for synthesis of wybutosine genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Synthetic Growth Defect
SIZ1 YDR409W SUMO E3 ligase genetic 1 1 1 Phenotypic Enhancement
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Positive Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
ISA1 YLL027W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Negative Genetic
SHH4 YLR164W Putative alternate subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Negative Genetic
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RPL18B YNL301C Ribosomal 60S subunit protein L18B genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase physical 1 1 1 Affinity Capture-MS
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth physical 1 1 1 Affinity Capture-MS
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly physical 1 1 1 Affinity Capture-MS