| TPK1 | YJL164C | cAMP-dependent protein kinase catalytic subunit | physical | 8 | 4 | 4 | Biochemical Activity, Two-hybrid, Two-hybrid, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity | 
            
                | RIM15 | YFL033C | Protein kinase involved in cell proliferation in response to nutrients | genetic | 7 | 3 | 6 | Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect | 
            
                | HSF1 | YGL073W | Trimeric heat shock transcription factor | regulation | 3 | 3 | 3 | protein kinase assay evidence, qualitative western immunoblotting evidence, reverse transcription polymerase chain reaction evidence | 
            
                | TPK2 | YPL203W | cAMP-dependent protein kinase catalytic subunit | genetic | 3 | 2 | 3 | Dosage Rescue, Dosage Rescue, Synthetic Rescue | 
            
                | TPK3 | YKL166C | cAMP-dependent protein kinase catalytic subunit | genetic | 3 | 2 | 3 | Dosage Rescue, Dosage Rescue, Synthetic Rescue | 
            
                | HSF1 | YGL073W | Trimeric heat shock transcription factor | physical | 3 | 1 | 3 | Biochemical Activity, Biochemical Activity, Biochemical Activity | 
            
                | BMH1 | YER177W | 14-3-3 protein, major isoform | physical | 3 | 2 | 2 | Affinity Capture-Western, Two-hybrid, Affinity Capture-Western | 
            
                | SIT4 | YDL047W | Ceramide-activated, type 2A-related serine-threonine phosphatase | genetic | 2 | 2 | 2 | Positive Genetic, Dosage Rescue | 
            
                | TPK2 | YPL203W | cAMP-dependent protein kinase catalytic subunit | physical | 2 | 2 | 2 | Biochemical Activity, Affinity Capture-MS | 
            
                | TPK1 | YJL164C | cAMP-dependent protein kinase catalytic subunit | genetic | 2 | 2 | 2 | Dosage Rescue, Synthetic Rescue | 
            
                | RAS2 | YNL098C | GTP-binding protein | genetic | 2 | 2 | 2 | Synthetic Rescue, Phenotypic Enhancement | 
            
                | DBF2 | YGR092W | Ser/Thr kinase involved in transcription and stress response | genetic | 2 | 2 | 2 | Dosage Rescue, Positive Genetic | 
            
                | MSN2 | YMR037C | Stress-responsive transcriptional activator | genetic | 2 | 2 | 2 | Dosage Rescue, Negative Genetic | 
            
                | SOK2 | YMR016C | Nuclear protein that negatively regulates pseudohyphal differentiation | genetic | 2 | 2 | 2 | Synthetic Rescue, Positive Genetic | 
            
                | SIN4 | YNL236W | Subunit of the RNA polymerase II mediator complex | genetic | 2 | 1 | 2 | Positive Genetic, Positive Genetic | 
            
                | ARP2 | YDL029W | Essential component of the Arp2/3 complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | UBP15 | YMR304W | Ubiquitin-specific protease involved in protein deubiquitination | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | YPL247C | YPL247C | Putative protein of unknown function | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | YAK1 | YJL141C | Serine-threonine protein kinase | physical | 2 | 1 | 2 | Biochemical Activity, Biochemical Activity | 
            
                | RAS1 | YOR101W | GTPase involved in G-protein signaling in adenylate cyclase activation | genetic | 2 | 1 | 2 | Synthetic Rescue, Synthetic Rescue | 
            
                | SHP1 | YBL058W | UBX domain-containing substrate adaptor for Cdc48p | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | UBI4 | YLL039C | Ubiquitin | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | SWE1 | YJL187C | Protein kinase that regulates the G2/M transition | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | SSN8 | YNL025C | Cyclin-like component of RNA polymerase II holoenzyme | genetic | 2 | 1 | 2 | Positive Genetic, Positive Genetic | 
            
                | BUB3 | YOR026W | Kinetochore checkpoint WD40 repeat protein | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | IME2 | YJL106W | Serine/threonine protein kinase involved in activation of meiosis | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | SWI6 | YLR182W | Transcription cofactor | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | KAR3 | YPR141C | Minus-end-directed microtubule motor | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | GLN3 | YER040W | Transcriptional activator in nitrogen catabolite repression system | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | TAP42 | YMR028W | Essential protein involved in the TOR signaling pathway | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | CRF1 | YDR223W | Transcriptional corepressor | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | DER1 | YBR201W | ER membrane protein that promotes export of misfolded polypeptides | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | VMA9 | YCL005W-A | Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | MSC1 | YML128C | Protein of unknown function | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | RML2 | YEL050C | Mitochondrial ribosomal protein of the large subunit (L2) | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | WSC4 | YHL028W | Endoplasmic reticulum (ER) membrane protein | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | POP2 | YNR052C | Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation | physical | 2 | 2 | 1 | Affinity Capture-Western, Biochemical Activity | 
            
                | MCK1 | YNL307C | Dual-specificity ser/thr and tyrosine protein kinase | genetic | 2 | 2 | 1 | Phenotypic Enhancement, Synthetic Growth Defect | 
            
                | AIM3 | YBR108W | Protein that inhibits barbed-end actin filament elongation | genetic | 2 | 1 | 1 | Negative Genetic, Negative Genetic | 
            
                | IXR1 | YKL032C | Transcriptional repressor that regulates hypoxic genes during normoxia | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation- exonuclease evidence | 
            
                | XBP1 | YIL101C | Transcriptional repressor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | SUA7 | YPR086W | Transcription factor TFIIB | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | SPT6 | YGR116W | Nucleosome remodeling protein | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | INO2 | YDR123C | Transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | MSN2 | YMR037C | Stress-responsive transcriptional activator | regulation | 1 | 1 | 1 | reverse transcription polymerase chain reaction evidence | 
            
                | CDC73 | YLR418C | Component of the Paf1p complex | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CDC40 | YDR364C | Pre-mRNA splicing factor | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | NSE4 | YDL105W | Component of the SMC5-SMC6 complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SAP155 | YFR040W | Protein required for function of the Sit4p protein phosphatase | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | SAP190 | YKR028W | Protein that forms a complex with the Sit4p protein phosphatase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | XRN1 | YGL173C | Evolutionarily-conserved 5'-3' exonuclease | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPA49 | YNL248C | RNA polymerase I subunit A49 | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | REI1 | YBR267W | Cytoplasmic pre-60S factor | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VIP1 | YLR410W | Bifunctional inositol pyrophosphate kinase and phosphatase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | CDC39 | YCR093W | Subunit of the CCR4-NOT1 core complex | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | NAB2 | YGL122C | Nuclear polyadenylated RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | APC1 | YNL172W | Largest subunit of the Anaphase-Promoting Complex/Cyclosome | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BEM1 | YBR200W | Protein containing SH3-domains | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BMH2 | YDR099W | 14-3-3 protein, minor isoform | physical | 1 | 1 | 1 | Affinity Capture-Western | 
            
                | CDC3 | YLR314C | Component of the septin ring that is required for cytokinesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BUD31 | YCR063W | Component of the SF3b subcomplex of the U2 snRNP | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | FKS1 | YLR342W | Catalytic subunit of 1,3-beta-D-glucan synthase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | GLY1 | YEL046C | Threonine aldolase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | HRT1 | YOL133W | RING-H2 domain core subunit of multiple ubiquitin ligase complexes | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | ISW1 | YBR245C | ATPase subunit of imitation-switch (ISWI) class chromatin remodelers | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | CRM1 | YGR218W | Nuclear export factor, exportin | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | GLT1 | YDL171C | NAD(+)-dependent glutamate synthase (GOGAT) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | GLT1 | YDL171C | NAD(+)-dependent glutamate synthase (GOGAT) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CMD1 | YBR109C | Calmodulin | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ARP8 | YOR141C | Nuclear actin-related protein involved in chromatin remodeling | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | IES5 | YER092W | Non-essential INO80 chromatin remodeling complex subunit | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | PPH22 | YDL188C | Catalytic subunit of protein phosphatase 2A, PP2A | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | PAA1 | YDR071C | Polyamine acetyltransferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MET18 | YIL128W | Component of cytosolic iron-sulfur protein assembly (CIA) machinery | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ILV1 | YER086W | Threonine deaminase, catalyzes first step in isoleucine biosynthesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RAM1 | YDL090C | Beta subunit of the CAAX farnesyltransferase (FTase) | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | PPH21 | YDL134C | Catalytic subunit of protein phosphatase 2A, PP2A | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CCT8 | YJL008C | Subunit of the cytosolic chaperonin Cct ring complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TAF1 | YGR274C | TFIID subunit, involved in RNA pol II transcription initiation | genetic | 1 | 1 | 1 | Synthetic Lethality | 
            
                | BCK1 | YJL095W | MAPKKK acting in the protein kinase C signaling pathway | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | BCK1 | YJL095W | MAPKKK acting in the protein kinase C signaling pathway | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VMA13 | YPR036W | Subunit H of the V1 peripheral membrane domain of V-ATPase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VMA7 | YGR020C | Subunit F of the V1 peripheral membrane domain of V-ATPase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SWD1 | YAR003W | Subunit of the COMPASS (Set1C) complex | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SDC1 | YDR469W | Subunit of the COMPASS (Set1C) complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | PUF3 | YLL013C | Protein of the mitochondrial outer surface | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | NOB1 | YOR056C | Protein involved in proteasomal and 40S ribosomal subunit biogenesis | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | DNM1 | YLL001W | Dynamin-related GTPase involved in mitochondrial organization | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | HYP2 | YEL034W | Translation elongation factor eIF-5A | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CAF20 | YOR276W | Phosphoprotein of the mRNA cap-binding complex | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CDC5 | YMR001C | Polo-like kinase required for mitotic exit | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | FOL2 | YGR267C | GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | DCS1 | YLR270W | Non-essential hydrolase involved in mRNA decapping | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | VPS1 | YKR001C | Dynamin-like GTPase required for vacuolar sorting | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | YJL206C | YJL206C | Putative protein of unknown function | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | YMR295C | YMR295C | Protein of unknown function that associates with ribosomes | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | YBL055C | YBL055C | 3'-->5' exonuclease and endonuclease with a possible role in apoptosis | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | YKL091C | YKL091C | Putative phosphatidylinositol/phosphatidylcholine transfer protein | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | YRA1 | YDR381W | Nuclear polyadenylated RNA-binding protein | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | YAP3 | YHL009C | Basic leucine zipper (bZIP) transcription factor | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YOR381W-A | YOR381W-A | Putative protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SPS1 | YDR523C | STE20-family GCKIII protein kinase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | AHP1 | YLR109W | Thiol-specific peroxiredoxin | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DUN1 | YDL101C | Cell-cycle checkpoint S/T protein kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | LCP5 | YER127W | Essential protein involved in maturation of 18S rRNA | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | HEF3 | YNL014W | Translational elongation factor EF-3 | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | TSA2 | YDR453C | Stress inducible cytoplasmic thioredoxin peroxidase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | ELA1 | YNL230C | Elongin A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DOP1 | YDR141C | Protein involved in vesicular transport at trans-Golgi network (TGN) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GDB1 | YPR184W | Glycogen debranching enzyme | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | KNS1 | YLL019C | Protein kinase involved in negative regulation of PolIII transcription | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MSI1 | YBR195C | Subunit of chromatin assembly factor I (CAF-1) | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | TSL1 | YML100W | Large subunit of trehalose 6-phosphate synthase/phosphatase complex | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | CIN8 | YEL061C | Bipolar kinesin motor protein | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | TEM1 | YML064C | GTPase involved in initiation of Mitotic Exit Network (MEN) | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | CDC15 | YAR019C | Hippo-like kinase of the Mitotic Exit Network | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | DIA2 | YOR080W | Origin-binding F-box protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RAD50 | YNL250W | Subunit of MRX complex with Mre11p and Xrs2p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | PAP2 | YOL115W | Non-canonical poly(A) polymerase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UBR1 | YGR184C | E3 ubiquitin ligase (N-recognin) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | FKH2 | YNL068C | Forkhead family transcription factor | genetic | 1 | 1 | 1 | Dosage Growth Defect | 
            
                | LSM8 | YJR022W | Lsm (Like Sm) protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CPR3 | YML078W | Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | DEF1 | YKL054C | RNAPII degradation factor | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SEF1 | YBL066C | Putative transcription factor | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | FUS3 | YBL016W | Mitogen-activated serine/threonine protein kinase involved in mating | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | DCS2 | YOR173W | m(7)GpppX pyrophosphatase regulator | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CSC1 | YLR241W | Calcium permeable gated cation channel | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CDH1 | YGL003C | Activator of anaphase-promoting complex/cyclosome (APC/C) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | NUP133 | YKR082W | Subunit of Nup84p subcomplex of nuclear pore complex (NPC) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SNF4 | YGL115W | Activating gamma subunit of the AMP-activated Snf1p kinase complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ESS1 | YJR017C | Peptidylprolyl-cis/trans-isomerase (PPIase) | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | ESS1 | YJR017C | Peptidylprolyl-cis/trans-isomerase (PPIase) | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | DCK1 | YLR422W | Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | MTQ2 | YDR140W | S-adenosylmethionine-dependent methyltransferase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SKA1 | YKL023W | SKI complex-associated protein | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | BIM1 | YER016W | Microtubule plus end-tracking protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GZF3 | YJL110C | GATA zinc finger protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HAA1 | YPR008W | Transcriptional activator involved in adaptation to weak acid stress | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | RIB4 | YOL143C | Lumazine synthase (DMRL synthase) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RLP24 | YLR009W | Essential protein required for ribosomal large subunit biogenesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPL23B | YER117W | Ribosomal 60S subunit protein L23B | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | AMD1 | YML035C | AMP deaminase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | SWR1 | YDR334W | Swi2/Snf2-related ATPase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MSN2 | YMR037C | Stress-responsive transcriptional activator | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | TAF9 | YMR236W | Subunit (17 kDa) of TFIID and SAGA complexes | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CBF1 | YJR060W | Basic helix-loop-helix (bHLH) protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPS11B | YBR048W | Protein component of the small (40S) ribosomal subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BUB1 | YGR188C | Protein kinase involved in the cell cycle checkpoint into anaphase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SWI4 | YER111C | DNA binding component of the SBF complex (Swi4p-Swi6p) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TIM22 | YDL217C | Essential core component of mitochondrial TIM22 complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HAP1 | YLR256W | Zinc finger transcription factor | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | GSY2 | YLR258W | Glycogen synthase | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | UBX7 | YBR273C | UBX (ubiquitin regulatory X) domain-containing protein | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | ARL3 | YPL051W | ARF-like small GTPase of the RAS superfamily | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | DOM34 | YNL001W | Protein that facilitates ribosomal subunit dissociation | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | HBT1 | YDL223C | Shmoo tip protein, substrate of Hub1p ubiquitin-like protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SSB2 | YNL209W | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone | physical | 1 | 1 | 1 | Co-purification | 
            
                | RPL28 | YGL103W | Ribosomal 60S subunit protein L28 | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MOG1 | YJR074W | Conserved nuclear protein that interacts with GTP-Gsp1p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CRF1 | YDR223W | Transcriptional corepressor | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | COX15 | YER141W | Heme a synthase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | IFH1 | YLR223C | Coactivator, regulates transcription of ribosomal protein (RP) genes | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | VMA21 | YGR105W | Integral membrane protein required for V-ATPase function | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | NFS1 | YCL017C | Cysteine desulfurase involved in iron-sulfur cluster biogenesis | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | KCS1 | YDR017C | Inositol hexakisphosphate and inositol heptakisphosphate kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UBP3 | YER151C | Ubiquitin-specific protease that cleaves Ub-protein fusions | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | ORC4 | YPR162C | Subunit of the origin recognition complex (ORC) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RDS2 | YPL133C | Transcription factor involved in regulating gluconeogenesis | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | RPL8B | YLL045C | Ribosomal 60S subunit protein L8A | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RTR1 | YER139C | Dual specificity protein phosphatase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | MSN4 | YKL062W | Stress-responsive transcriptional activator | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | PTK2 | YJR059W | Serine/threonine protein kinase | physical | 1 | 1 | 1 | Biochemical Activity | 
            
                | RDR1 | YOR380W | Transcriptional repressor involved in regulating multidrug resistance | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SCH9 | YHR205W | AGC family protein kinase | genetic | 1 | 1 | 1 | Phenotypic Enhancement | 
            
                | MTG2 | YHR168W | Putative GTPase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PHD1 | YKL043W | Transcriptional activator that enhances pseudohyphal growth | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | NCB2 | YDR397C | Subunit of a heterodimeric NC2 transcription regulator complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SIC1 | YLR079W | Cyclin-dependent kinase inhibitor (CKI) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ADK2 | YER170W | Mitochondrial adenylate kinase | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | VOA1 | YGR106C | ER protein that functions in assembly of the V0 sector of V-ATPase | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | WHI3 | YNL197C | RNA binding protein that modulates mRNA stability | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | NFU1 | YKL040C | Protein involved in Fe-S cluster transfer to mitochondrial clients | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | AVL9 | YLR114C | Conserved protein involved in exocytic transport from the Golgi | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | LCB4 | YOR171C | Sphingoid long-chain base kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SWS2 | YNL081C | Putative mitochondrial ribosomal protein of the small subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | JLP2 | YMR132C | Protein of unknown function | genetic | 1 | 1 | 1 | Dosage Growth Defect | 
            
                | IMP2 | YMR035W | Catalytic subunit of mitochondrial inner membrane peptidase complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UFO1 | YML088W | F-box receptor protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VMS1 | YDR049W | Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SMA2 | YML066C | Meiosis-specific prospore membrane protein | genetic | 1 | 1 | 1 | Negative Genetic |