| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
8 |
4 |
4 |
Biochemical Activity, Two-hybrid, Two-hybrid, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
7 |
3 |
6 |
Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
3 |
3 |
3 |
protein kinase assay evidence, qualitative western immunoblotting evidence, reverse transcription polymerase chain reaction evidence |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
physical |
3 |
1 |
3 |
Biochemical Activity, Biochemical Activity, Biochemical Activity |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
2 |
2 |
2 |
Positive Genetic, Dosage Rescue |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Rescue |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Enhancement |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YPL247C |
YPL247C |
Putative protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YAK1 |
YJL141C |
Serine-threonine protein kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CRF1 |
YDR223W |
Transcriptional corepressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WSC4 |
YHL028W |
Endoplasmic reticulum (ER) membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| INO2 |
YDR123C |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
reverse transcription polymerase chain reaction evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLY1 |
YEL046C |
Threonine aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HRT1 |
YOL133W |
RING-H2 domain core subunit of multiple ubiquitin ligase complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA7 |
YGR020C |
Subunit F of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| FOL2 |
YGR267C |
GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YJL206C |
YJL206C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR381W-A |
YOR381W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPS1 |
YDR523C |
STE20-family GCKIII protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HEF3 |
YNL014W |
Translational elongation factor EF-3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELA1 |
YNL230C |
Elongin A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDB1 |
YPR184W |
Glycogen debranching enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR3 |
YML078W |
Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEF1 |
YBL066C |
Putative transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCS2 |
YOR173W |
m(7)GpppX pyrophosphatase regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSC1 |
YLR241W |
Calcium permeable gated cation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DCK1 |
YLR422W |
Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SKA1 |
YKL023W |
SKI complex-associated protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RIB4 |
YOL143C |
Lumazine synthase (DMRL synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP1 |
YLR256W |
Zinc finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GSY2 |
YLR258W |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRF1 |
YDR223W |
Transcriptional corepressor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COX15 |
YER141W |
Heme a synthase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RDR1 |
YOR380W |
Transcriptional repressor involved in regulating multidrug resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MTG2 |
YHR168W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADK2 |
YER170W |
Mitochondrial adenylate kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JLP2 |
YMR132C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFO1 |
YML088W |
F-box receptor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |