Standard name Systematic name Name description Description
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT2 has a paralog, EFT1, that arose from the whole genome duplication
Visualize the interactome of EFT2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 0.996 0.986
Cell Periphery NaN NaN 0.062

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 78100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
EFT2 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM1 YJL124C Lsm (Like Sm) protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect
JJJ3 YJR097W Iron-binding protein genetic 5 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 4 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KIN4 YOR233W Serine/threonine protein kinase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DPH6 YLR143W Diphthamide synthetase genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YJL068C YJL068C Esterase that can function as an S-formylglutathione hydrolase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPH1 YIL103W Protein required for synthesis of diphthamide genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
DPH2 YKL191W Protein required for synthesis of diphthamide physical 2 2 2 Affinity Capture-MS, PCA
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide physical 2 2 2 PCA, Affinity Capture-Western
EFM2 YBR271W S-adenosylmethionine-dependent methyltransferase regulation 2 1 2 mass spectrometry evidence, mass spectrometry evidence
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 2 1 2 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 2 1 2 Negative Genetic, Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 2 1 2 Negative Genetic, Negative Genetic
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 2 1 2 Negative Genetic, Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 2 1 2 Negative Genetic, Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes regulation 1 1 1 chromatin immunoprecipitation-seq evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Affinity Capture-Western
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Two-hybrid
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
HEM13 YDR044W Coproporphyrinogen III oxidase physical 1 1 1 Affinity Capture-MS
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 1 1 1 Affinity Capture-MS
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity physical 1 1 1 Affinity Capture-MS
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Affinity Capture-MS
RAD33 YML011C Protein involved in nucleotide excision repair physical 1 1 1 Affinity Capture-MS
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly physical 1 1 1 Affinity Capture-MS
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Affinity Capture-MS
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Affinity Capture-MS
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
YLF2 YHL014C Protein of unknown function physical 1 1 1 Affinity Capture-MS
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 1 1 1 Affinity Capture-MS
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-MS
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 PCA
LSP1 YPL004C Eisosome core component physical 1 1 1 PCA
INO1 YJL153C Inositol-3-phosphate synthase physical 1 1 1 PCA
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity physical 1 1 1 PCA
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Affinity Capture-MS
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p physical 1 1 1 Two-hybrid
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 1 1 1 Synthetic Lethality
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-MS
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
GID7 YCL039W Subunit of GID Complex that binds directly to central component Vid30p physical 1 1 1 Affinity Capture-MS
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Affinity Capture-MS
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
YGP1 YNL160W Cell wall-related secretory glycoprotein physical 1 1 1 Affinity Capture-MS
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
NDE2 YDL085W Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
RPL34B YIL052C Ribosomal 60S subunit protein L34B physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Positive Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Positive Genetic
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Positive Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
GFD2 YCL036W Protein of unknown function genetic 1 1 1 Negative Genetic
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Negative Genetic
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Negative Genetic
YLR345W YLR345W Similar to 6-phosphofructo-2-kinase enzymes genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DUR12 YBR208C Urea amidolyase genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-Western
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Affinity Capture-MS
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway physical 1 1 1 Affinity Capture-MS
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
DPH1 YIL103W Protein required for synthesis of diphthamide physical 1 1 1 Affinity Capture-MS
DPH6 YLR143W Diphthamide synthetase physical 1 1 1 Affinity Capture-Western
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
AIM22 YJL046W Lipoate-protein ligase physical 1 1 1 Affinity Capture-MS
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
ADE12 YNL220W Adenylosuccinate synthase genetic 1 1 1 Positive Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 1 1 1 Affinity Capture-MS
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
DSC2 YOL073C Multi-transmembrane subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Negative Genetic
EFM3 YJR129C S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Biochemical Activity
ECM14 YHR132C Conserved fungal protein with similarity to zinc carboxypeptidases genetic 1 1 1 Negative Genetic