| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
12 |
3 |
11 |
Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
7 |
4 |
6 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue, Phenotypic Suppression, Negative Genetic, Dosage Rescue, Phenotypic Suppression |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
physical |
6 |
3 |
5 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, PCA |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
6 |
3 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Growth Defect |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
physical |
6 |
3 |
3 |
Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
physical |
5 |
4 |
5 |
Affinity Capture-Western, Two-hybrid, Reconstituted Complex, PCA, Reconstituted Complex |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
physical |
5 |
4 |
5 |
Two-hybrid, Two-hybrid, Biochemical Activity, PCA, Reconstituted Complex |
| MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
genetic |
4 |
1 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
4 |
2 |
3 |
Phenotypic Suppression, Dosage Rescue, Dosage Rescue, Phenotypic Suppression |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
3 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
3 |
3 |
3 |
Dosage Rescue, Phenotypic Suppression, Negative Genetic |
| BNI1 |
YNL271C |
Formin |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, PCA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
3 |
2 |
Negative Genetic, Synthetic Rescue, Phenotypic Suppression |
| KOG1 |
YHR186C |
Subunit of TORC1 |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
| OCH1 |
YGL038C |
Mannosyltransferase of the cis-Golgi apparatus |
genetic |
3 |
2 |
2 |
Dosage Rescue, Phenotypic Suppression, Dosage Rescue |
| MTL1 |
YGR023W |
Putative plasma membrane sensor |
genetic |
3 |
2 |
2 |
Dosage Rescue, Phenotypic Suppression, Dosage Rescue |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
3 |
1 |
2 |
Dosage Rescue, Dosage Rescue, Dosage Rescue |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
2 |
2 |
2 |
Co-purification, Co-fractionation |
| ROM1 |
YGR070W |
Guanine nucleotide exchange factor (GEF) for Rho1p |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Rescue |
| BAG7 |
YOR134W |
Rho GTPase activating protein (RhoGAP) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Two-hybrid |
| MSB1 |
YOR188W |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Dosage Rescue, Dosage Growth Defect |
| STE4 |
YOR212W |
G protein beta subunit |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Rescue |
| DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| YCF1 |
YDR135C |
Vacuolar glutathione S-conjugate transporter |
physical |
2 |
2 |
1 |
PCA, FRET |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Dosage Rescue |
| SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Dosage Rescue |
| YPK1 |
YKL126W |
S/T protein kinase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Phenotypic Suppression |
| YPK2 |
YMR104C |
AGC-type S/T protein kinase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Phenotypic Suppression |
| DMA1 |
YHR115C |
Ubiquitin-protein ligase (E3) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Phenotypic Suppression |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
physical |
2 |
2 |
1 |
Reconstituted Complex, PCA |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
| ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
| LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
physical |
1 |
1 |
1 |
Co-fractionation |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSH2 |
YDL019C |
Member of an oxysterol-binding protein family with seven members |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WTM1 |
YOR230W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE4 |
YOR212W |
G protein beta subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SHC1 |
YER096W |
Sporulation-specific activator of Chs3p (chitin synthase III) |
physical |
1 |
1 |
1 |
Two-hybrid |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
physical |
1 |
1 |
1 |
PCA |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SPA2 |
YLL021W |
Component of the polarisome |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| WSC3 |
YOL105C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB1 |
YML085C |
Alpha-tubulin |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUM1 |
YPL262W |
Fumarase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NAS2 |
YIL007C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ART5 |
YGR068C |
Protein proposed to regulate endocytosis of plasma membrane proteins |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MSB3 |
YNL293W |
Rab GTPase-activating protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PXL1 |
YKR090W |
Protein that localizes to sites of polarized growth |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PXL1 |
YKR090W |
Protein that localizes to sites of polarized growth |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSB1 |
YOR188W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSH7 |
YHR001W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OSH6 |
YKR003W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO1 |
YER026C |
Phosphatidylserine synthase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HES1 |
YOR237W |
Protein implicated in the regulation of ergosterol biosynthesis |
genetic |
1 |
1 |
1 |
Dosage Lethality |