| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| REX4 |
YOL080C |
Putative RNA exonuclease |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DPB3 |
YBR278W |
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RMD1 |
YDL001W |
Cytoplasmic protein required for sporulation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
2 |
1 |
2 |
PCA, PCA |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DTD1 |
YDL219W |
D-Tyr-tRNA(Tyr) deacylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRP15 |
YPR143W |
Nucleolar protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
| MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSA3 |
YLR221C |
Protein with a likely role in ribosomal maturation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP4 |
YPL043W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
1 |
1 |
1 |
PCA |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP14 |
YKL082C |
Essential protein, constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
physical |
1 |
1 |
1 |
PCA |
| NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP3 |
YDR473C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP43 |
YCR035C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RLI1 |
YDR091C |
Essential Fe-S protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF130 |
YGR134W |
Subunit of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LTV1 |
YKL143W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYM1 |
YDR430C |
Lysine-specific metalloprotease of the pitrilysin family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD5 |
YJR132W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GSP2 |
YOR185C |
GTP binding protein (mammalian Ranp homolog) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PXR1 |
YGR280C |
Essential protein involved in rRNA and snoRNA maturation |
physical |
1 |
1 |
1 |
PCA |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS111 |
YBR203W |
Protein required for antifungal drug ciclopirox olamine resistance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL3 |
YDR009W |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIR1 |
YIL079C |
Zinc knuckle protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNO1 |
YMR095C |
Protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDD1 |
YLR245C |
Cytidine deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBD2 |
YPL246C |
Possible rhomboid protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO2 |
YMR068W |
Component of a complex containing the Tor2p kinase and other proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWC7 |
YLR385C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX11 |
YOL147C |
Peroxisomal protein required for medium-chain fatty acid oxidation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU13 |
YEL026W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RUP1 |
YOR138C |
Protein that regulates ubiquitination of Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANT1 |
YPR128C |
Peroxisomal adenine nucleotide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INA22 |
YIR024C |
F1F0 ATP synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRD1 |
YEL047C |
Soluble fumarate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OXP1 |
YKL215C |
5-oxoprolinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM23 |
YJL131C |
Mitochondrial translation initiation factor 3 (IF3, mIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PYP1 |
YNL010W |
Sugar alcohol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP45 |
YDL222C |
Integral membrane protein localized to mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASP3-4 |
YLR160C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP32 |
YPL280W |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPC2 |
YHR162W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPI35 |
YMR130W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NRK1 |
YNL129W |
Nicotinamide riboside kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHQ1 |
YIL104C |
Chaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAN1 |
YGL232W |
Putative tRNA acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO24 |
YPR036W-A |
Small (67 amino acids) protein involved in sporulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PZF1 |
YPR186C |
Transcription factor IIIA (TFIIIA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI4 |
YDL224C |
Putative RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM2 |
YKR056W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTR5 |
YEL035C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKR011C |
YKR011C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT2 |
YLR130C |
Low-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT53 |
YNL093W |
Stress-induced Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL108C |
YNL108C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
