Standard name Systematic name Name description Description
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36
Visualize the interactome of UBP10
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.112 0.071 NaN
Nucleolus 0.812 0.717 0.592
Nucleus 0.215 0.196 0.359
Endosome NaN 0.050 NaN
Vac/Vac Memb NaN 0.083 NaN
SpindlePole NaN NaN 0.067

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
UBP10 5 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 7 4 5 Two-hybrid, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 6 1 6 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 6 3 5 Affinity Capture-MS, PCA, PCA, Two-hybrid, Affinity Capture-MS, Two-hybrid
UTP22 YGR090W Component of the small-subunit processome physical 4 2 3 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid
HTB1 YDR224C Histone H2B physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 3 3 2 Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
YDR249C YDR249C Putative protein of unknown function genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
NOC2 YOR206W Protein involved in ribosome biogenesis physical 2 2 2 PCA, Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 2 2 2 Affinity Capture-MS, Biochemical Activity
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 2 2 2 PCA, Affinity Capture-MS
HTB1 YDR224C Histone H2B genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 2 2 2 Biochemical Activity, Reconstituted Complex
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 2 2 2 PCA, Affinity Capture-MS
UBP6 YFR010W Ubiquitin-specific protease genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 2 2 1 Biochemical Activity, Affinity Capture-MS
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 2 1 Synthetic Growth Defect, Synthetic Rescue
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 2 2 1 Reconstituted Complex, Two-hybrid
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) regulation 1 1 1 immunodetection assay evidence
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-Western
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Growth Defect
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Affinity Capture-MS
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP4 YPL043W Nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 PCA
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 PCA
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Phenotypic Suppression
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
DIP2 YLR129W Nucleolar protein physical 1 1 1 PCA
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 PCA
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 PCA
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 PCA
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
RRP9 YPR137W Protein involved in pre-rRNA processing physical 1 1 1 PCA
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Dosage Rescue
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Growth Defect
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Phenotypic Suppression
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GLY1 YEL046C Threonine aldolase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B genetic 1 1 1 Synthetic Rescue
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Positive Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Affinity Capture-MS
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Biochemical Activity
HTA2 YBL003C Histone H2A physical 1 1 1 Biochemical Activity
MIR1 YJR077C Mitochondrial phosphate carrier physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Phenotypic Suppression
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 1 1 1 Affinity Capture-MS
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 1 1 1 Protein-peptide
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Phenotypic Suppression
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Biochemical Activity
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
PYC2 YBR218C Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-MS
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Reconstituted Complex
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Affinity Capture-MS
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 PCA
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase physical 1 1 1 Affinity Capture-MS
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
PDS1 YDR113C Securin physical 1 1 1 Biochemical Activity
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Biochemical Activity
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Phenotypic Suppression
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
KIN2 YLR096W S/T protein kinase physical 1 1 1 Biochemical Activity
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 Biochemical Activity
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
SEC4 YFL005W Rab family GTPase physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Biochemical Activity
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 1 1 1 PCA
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Biochemical Activity
CHZ1 YER030W Histone chaperone for Htz1p/H2A-H2B dimer genetic 1 1 1 Synthetic Growth Defect
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Biochemical Activity
SIR3 YLR442C Silencing protein physical 1 1 1 Reconstituted Complex
SIR3 YLR442C Silencing protein genetic 1 1 1 Phenotypic Suppression
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Protein-peptide
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies genetic 1 1 1 Negative Genetic
RBD2 YPL246C Possible rhomboid protease genetic 1 1 1 Positive Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RIF1 YBR275C Protein involved in control of DNA replication genetic 1 1 1 Phenotypic Suppression
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 1 1 1 Reconstituted Complex
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Phenotypic Suppression
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Affinity Capture-MS
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Biochemical Activity
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Positive Genetic
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Biochemical Activity
SCO2 YBR024W Protein anchored to mitochondrial inner membrane genetic 1 1 1 Negative Genetic
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Affinity Capture-MS
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
ASN2 YGR124W Asparagine synthetase physical 1 1 1 Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Negative Genetic
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
WWM1 YFL010C WW domain containing protein of unknown function physical 1 1 1 Protein-peptide
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme physical 1 1 1 Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Affinity Capture-MS
UTP13 YLR222C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Phenotypic Suppression
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Phenotypic Enhancement
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide physical 1 1 1 Affinity Capture-MS
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Biochemical Activity
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Phenotypic Suppression
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
GMC2 YLR445W Protein involved in meiotic crossing over genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Positive Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins genetic 1 1 1 Positive Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic