Standard name Systematic name Name description Description
MYO5 YMR109W One of two type I myosin motors One of two type I myosin motors; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO5 has a paralog, MYO3, that arose from the whole genome duplication
Visualize the interactome of MYO5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.194 0.184 0.233
Cell Periphery 0.100 NaN NaN
Cort. Patches 0.696 0.510 0.672
Cytoplasm 0.100 0.163 0.060
Golgi 0.225 NaN NaN
Mito 0.073 0.449 0.526
Peroxisome 0.083 0.102 0.267
Budsite NaN 0.061 0.103
ER NaN 0.082 NaN
Endosome NaN 0.061 NaN
Vac/Vac Memb NaN 0.061 NaN

GFP localization & abundance

GFP localization GFP abundance
actin 2280

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MYO5 0 0 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VRP1 YLR337C Verprolin, proline-rich actin-associated protein physical 15 5 11 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-localization, PCA, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid
MYO3 YKL129C One of two type I myosins genetic 12 4 11 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
LAS17 YOR181W Actin assembly factor physical 10 6 9 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-Luminescence
CMD1 YBR109C Calmodulin physical 8 3 7 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 7 3 6 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 7 4 4 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Two-hybrid
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 6 3 5 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 6 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 6 5 4 Synthetic Lethality, Dosage Rescue, Phenotypic Enhancement, Positive Genetic, Negative Genetic, Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 6 4 4 Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 5 3 5 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 5 4 4 Affinity Capture-MS, PCA, Two-hybrid, Two-hybrid, Affinity Capture-Western
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain physical 5 3 3 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid
ARC40 YBR234C Subunit of the ARP2/3 complex physical 4 3 4 Two-hybrid, Reconstituted Complex, PCA, Two-hybrid
MYO5 YMR109W One of two type I myosin motors physical 4 3 4 Two-hybrid, PCA, Two-hybrid, Affinity Capture-MS
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 4 3 3 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CMD1 YBR109C Calmodulin genetic 4 2 3 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, PCA
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 3 2 3 Two-hybrid, PCA, Two-hybrid
MYO3 YKL129C One of two type I myosins physical 3 2 3 Two-hybrid, Affinity Capture-MS, Two-hybrid
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 2 3 Dosage Lethality, Negative Genetic, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 3 3 2 Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex physical 3 3 2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
ARC15 YIL062C Subunit of the ARP2/3 complex physical 2 2 2 Affinity Capture-Western, PCA
ARC18 YLR370C Subunit of the ARP2/3 complex physical 2 2 2 Affinity Capture-Western, PCA
ARC19 YKL013C Subunit of the ARP2/3 complex physical 2 2 2 Affinity Capture-Western, Two-hybrid
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 2 2 2 Affinity Capture-MS, Two-hybrid
YGL242C YGL242C Protein of unknown function physical 2 2 2 Affinity Capture-MS, PCA
BNR1 YIL159W Formin genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 2 1 2 Two-hybrid, Two-hybrid
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 2 1 2 Negative Genetic, Negative Genetic
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 2 1 2 Two-hybrid, Two-hybrid
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall physical 2 1 2 Two-hybrid, Two-hybrid
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 2 1 2 Positive Genetic, Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 2 Positive Genetic, Positive Genetic
BNR1 YIL159W Formin physical 2 1 2 Two-hybrid, Two-hybrid
CLC1 YGR167W Clathrin light chain genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
YPK2 YMR104C AGC-type S/T protein kinase physical 2 2 1 Two-hybrid, Reconstituted Complex
OSH3 YHR073W Member of an oxysterol-binding protein family physical 2 2 1 Two-hybrid, Affinity Capture-Western
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 1 1 Negative Genetic, Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 1 1 Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 2 1 1 Negative Genetic, Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 2 1 1 Negative Genetic, Negative Genetic
YGL242C YGL242C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YPK2 YMR104C AGC-type S/T protein kinase regulation 1 1 1 protein kinase assay evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Phenotypic Suppression
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Two-hybrid
ARC35 YNR035C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-Western
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 Two-hybrid
BNI1 YNL271C Formin genetic 1 1 1 Phenotypic Enhancement
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Two-hybrid
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
ATG3 YNR007C E2-like enzyme physical 1 1 1 Two-hybrid
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
HER1 YOR227W Protein of unknown function physical 1 1 1 Two-hybrid
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Two-hybrid
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Dosage Growth Defect
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Two-hybrid
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Two-hybrid
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 1 1 1 Phenotypic Suppression
HTB1 YDR224C Histone H2B genetic 1 1 1 Negative Genetic
MPC54 YOR177C Component of the meiotic outer plaque genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Two-hybrid
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Positive Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Two-hybrid
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 Two-hybrid
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Two-hybrid
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Two-hybrid
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 Two-hybrid
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
PKH1 YDR490C Serine/threonine protein kinase physical 1 1 1 Two-hybrid
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Two-hybrid
PKH2 YOL100W Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
YPK2 YMR104C AGC-type S/T protein kinase genetic 1 1 1 Phenotypic Enhancement
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-MS
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 1 1 1 PCA
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 1 1 1 Two-hybrid
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 Two-hybrid
SAP1 YER047C Putative ATPase of the AAA family physical 1 1 1 Two-hybrid
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 1 1 1 Two-hybrid
YGR210C YGR210C Putative protein of unknown function physical 1 1 1 Two-hybrid
YIL092W YIL092W Putative protein of unknown function physical 1 1 1 Two-hybrid
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Two-hybrid
RTT106 YNL206C Histone chaperone physical 1 1 1 Two-hybrid
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme physical 1 1 1 Two-hybrid
STD1 YOR047C Protein involved in control of glucose-regulated gene expression physical 1 1 1 Two-hybrid
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-Western
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
UBP5 YER144C Putative ubiquitin-specific protease genetic 1 1 1 Dosage Rescue
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme genetic 1 1 1 Negative Genetic
PRY2 YKR013W Sterol binding protein involved in the export of acetylated sterols genetic 1 1 1 Positive Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Positive Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Positive Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Positive Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
YSC83 YHR017W Non-essential mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Negative Genetic
MET31 YPL038W Zinc-finger DNA-binding transcription factor physical 1 1 1 Two-hybrid
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein physical 1 1 1 Two-hybrid
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase physical 1 1 1 Two-hybrid
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Dosage Growth Defect
MET1 YKR069W S-adenosyl-L-methionine uroporphyrinogen III transmethylase physical 1 1 1 Two-hybrid
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 Two-hybrid
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
IMO32 YGR031W Conserved mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Positive Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Dosage Rescue
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Positive Genetic
DDI3 YFL061W Cyanamide hydratase that detoxifies cyanamide genetic 1 1 1 Negative Genetic