| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
12 |
5 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, FRET, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
8 |
3 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
7 |
3 |
6 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality |
| NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
7 |
4 |
5 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, FRET, FRET, Affinity Capture-Western, Affinity Capture-MS |
| ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
6 |
3 |
5 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
4 |
3 |
4 |
Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-MS |
| NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
3 |
3 |
3 |
Two-hybrid, Reconstituted Complex, Affinity Capture-MS |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
physical |
3 |
3 |
3 |
Two-hybrid, Affinity Capture-MS, Reconstituted Complex |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
3 |
3 |
2 |
Positive Genetic, Synthetic Growth Defect, Synthetic Lethality |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Two-hybrid |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| RNP1 |
YLL046C |
Ribonucleoprotein that contains two RNA recognition motifs (RRM) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Suppression |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG8 |
YBL078C |
Ub-like protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| HEH2 |
YDR458C |
Inner nuclear membrane (INM) protein |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Synthetic Growth Defect |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BLM10 |
YFL007W |
Proteasome activator |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PML1 |
YLR016C |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POM33 |
YLL023C |
Transmembrane nucleoporin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RTP1 |
YMR185W |
Protein required for the nuclear import and biogenesis of RNA pol II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC17 |
YJL011C |
RNA polymerase III subunit C17 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP54 |
YPR088C |
Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL086W |
YDL086W |
Putative carboxymethylenebutenolidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR289W |
YOR289W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Two-hybrid |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTL1 |
YMR180C |
RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ALF1 |
YNL148C |
Alpha-tubulin folding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP42 |
YDR192C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EKI1 |
YDR147W |
Ethanolamine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Negative Genetic |
