Standard name Systematic name Name description Description
GIS1 YDR096W Histone demethylase and transcription factor Histone demethylase and transcription factor; regulates genes during nutrient limitation; activity modulated by proteasome-mediated proteolysis; has JmjC and JmjN domain in N-terminus that interact, promoting stability and proper transcriptional activity; contains two transactivating domains downstream of Jmj domains and a C-terminal DNA binding domain; relocalizes to the cytosol in response to hypoxia; GIS1 has a paralog, RPH1, that arose from the whole genome duplication
Visualize the interactome of GIS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 160

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.062 NaN 0.099
Mito 0.233 0.186 NaN
Nucleolus 0.085 NaN NaN
Nucleus 0.868 0.881 0.818
SpindlePole NaN NaN 0.075

GFP localization & abundance

GFP localization GFP abundance
nucleus 432

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GIS1 6 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MSN4 YKL062W Stress-responsive transcriptional activator genetic 8 4 6 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
MSN2 YMR037C Stress-responsive transcriptional activator genetic 7 3 5 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
RPH1 YER169W JmjC domain-containing histone demethylase genetic 5 2 5 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 4 3 2 Phenotypic Suppression, Dosage Rescue, Synthetic Rescue, Phenotypic Suppression
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 3 3 3 Dosage Lethality, Dosage Rescue, Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 3 2 3 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression
HHF1 YBR009C Histone H4 genetic 3 3 2 Negative Genetic, Phenotypic Suppression, Phenotypic Enhancement
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 3 2 2 Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression
SSD1 YDR293C Translational repressor physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 2 1 2 Negative Genetic, Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MSC1 YML128C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
KIN1 YDR122W S/T protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
UBI4 YLL039C Ubiquitin genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 2 2 1 Two-hybrid, Affinity Capture-Western
JIP5 YPR169W Protein required for biogenesis of the large ribosomal subunit physical 2 2 1 Two-hybrid, Affinity Capture-Western
TAF8 YML114C TFIID subunit (65 kDa) physical 2 2 1 Two-hybrid, Affinity Capture-Western
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 2 2 1 Affinity Capture-Western, Biochemical Activity
MOT3 YMR070W Transcriptional repressor, activator physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PBP4 YDL053C Pbp1p binding protein physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Two-hybrid
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Positive Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-Western
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor physical 1 1 1 Affinity Capture-MS
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Affinity Capture-MS
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Dosage Lethality
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ATG18 YFR021W Phosphoinositide binding protein physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Affinity Capture-MS
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Negative Genetic
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase physical 1 1 1 Affinity Capture-MS
DLD3 YEL071W 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase physical 1 1 1 Affinity Capture-MS
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III physical 1 1 1 Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 Affinity Capture-MS
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
DUF1 YOL087C Ubiquitin-binding protein of unknown function physical 1 1 1 Affinity Capture-MS
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes physical 1 1 1 Two-hybrid
CSM3 YMR048W Replication fork associated factor physical 1 1 1 Two-hybrid
ATG34 YOL083W Receptor protein involved in selective autophagy during starvation genetic 1 1 1 Positive Genetic
BUD5 YCR038C GTP/GDP exchange factor for Rsr1p (Bud1p) physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
ERV41 YML067C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Two-hybrid
FIR1 YER032W Protein involved in 3' mRNA processing physical 1 1 1 Two-hybrid
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Negative Genetic
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase physical 1 1 1 Affinity Capture-MS
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
ADE12 YNL220W Adenylosuccinate synthase genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) physical 1 1 1 Affinity Capture-MS
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Negative Genetic
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector physical 1 1 1 Affinity Capture-MS
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Two-hybrid
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 1 1 1 Two-hybrid
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Two-hybrid
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Two-hybrid
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription physical 1 1 1 Two-hybrid
NIS1 YNL078W Protein involved in axial bud site selection physical 1 1 1 Two-hybrid
ZRG8 YER033C Protein of unknown function physical 1 1 1 Two-hybrid
PIG2 YIL045W Putative type-1 protein phosphatase targeting subunit physical 1 1 1 Two-hybrid
JIP4 YDR475C Protein of unknown function physical 1 1 1 Two-hybrid
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity physical 1 1 1 Two-hybrid
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Two-hybrid
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
GOR1 YNL274C Glyoxylate reductase physical 1 1 1 Affinity Capture-MS
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 Affinity Capture-MS
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs physical 1 1 1 Affinity Capture-MS
HIT1 YJR055W Protein involved in C/D snoRNP assembly physical 1 1 1 Affinity Capture-MS
HPA3 YEL066W D-Amino acid N-acetyltransferase that detoxifies D-amino acids physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex physical 1 1 1 Affinity Capture-MS
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase physical 1 1 1 Affinity Capture-MS
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Dosage Rescue
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPS12 YNR036C Mitochondrial protein physical 1 1 1 Affinity Capture-MS
MSC3 YLR219W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Affinity Capture-MS
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
OSH3 YHR073W Member of an oxysterol-binding protein family physical 1 1 1 Affinity Capture-MS
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Affinity Capture-MS
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
PHO8 YDR481C Repressible vacuolar alkaline phosphatase physical 1 1 1 Affinity Capture-MS
POL4 YCR014C DNA polymerase IV physical 1 1 1 Affinity Capture-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Affinity Capture-MS
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
SNX41 YDR425W Sorting nexin physical 1 1 1 Affinity Capture-MS
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Affinity Capture-MS
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response physical 1 1 1 Affinity Capture-MS
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
TOS1 YBR162C Covalently-bound cell wall protein of unknown function physical 1 1 1 Affinity Capture-MS
UTR1 YJR049C ATP-NADH kinase physical 1 1 1 Affinity Capture-MS
YBL081W YBL081W Non-essential protein of unknown function physical 1 1 1 Affinity Capture-MS
YCL020W YCL020W Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPK2 YMR104C AGC-type S/T protein kinase physical 1 1 1 Affinity Capture-MS
YPL247C YPL247C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles physical 1 1 1 Affinity Capture-MS
HEM15 YOR176W Ferrochelatase physical 1 1 1 Affinity Capture-MS
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor physical 1 1 1 Affinity Capture-MS
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 1 1 1 Affinity Capture-MS
IRC22 YEL001C Protein of unknown function physical 1 1 1 Affinity Capture-MS
IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 1 1 1 Affinity Capture-MS
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Affinity Capture-MS
MIG3 YER028C Transcriptional regulator physical 1 1 1 Affinity Capture-MS
MLF3 YNL074C Serine-rich protein of unknown function physical 1 1 1 Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase physical 1 1 1 Affinity Capture-MS
MSC1 YML128C Protein of unknown function physical 1 1 1 Affinity Capture-MS
NAM9 YNL137C Mitochondrial ribosomal component of the small subunit physical 1 1 1 Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Affinity Capture-MS
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate physical 1 1 1 Affinity Capture-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RNH1 YMR234W Ribonuclease H1 physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RRP3 YHR065C Protein involved in rRNA processing physical 1 1 1 Affinity Capture-MS
RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Affinity Capture-MS
SHE1 YBL031W Mitotic spindle protein physical 1 1 1 Affinity Capture-MS
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex physical 1 1 1 Affinity Capture-MS
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
SOK1 YDR006C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SRB4 YER022W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SSO1 YPL232W Plasma membrane t-SNARE physical 1 1 1 Affinity Capture-MS
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Affinity Capture-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
YBL086C YBL086C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YCR087C-A YCR087C-A Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
GUA1 YMR217W GMP synthase physical 1 1 1 Affinity Capture-MS
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Affinity Capture-MS
NMA1 YLR328W Nicotinic acid mononucleotide adenylyltransferase physical 1 1 1 Affinity Capture-MS
NMA2 YGR010W Nicotinic acid mononucleotide adenylyltransferase physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 Affinity Capture-MS
OPY1 YBR129C Protein of unknown function physical 1 1 1 Affinity Capture-MS
PAL2 YHR097C Protein involved in clathrin-mediated endocytosis physical 1 1 1 Affinity Capture-MS
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Dosage Rescue
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
SRV2 YNL138W CAP (cyclase-associated protein) physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Affinity Capture-MS
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-MS
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine physical 1 1 1 Affinity Capture-MS
YBR238C YBR238C Mitochondrial membrane protein physical 1 1 1 Affinity Capture-MS
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Affinity Capture-MS
YGR237C YGR237C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Dosage Lethality
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Dosage Rescue
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Dosage Rescue
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Dosage Rescue
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Synthetic Rescue
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
JHD1 YER051W JmjC domain family histone demethylase specific for H3-K36 genetic 1 1 1 Phenotypic Enhancement
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
YBR053C YBR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
MET13 YGL125W Major isozyme of methylenetetrahydrofolate reductase genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Negative Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Negative Genetic
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane genetic 1 1 1 Phenotypic Suppression
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
NOP13 YNL175C Nucleolar protein found in preribosomal complexes genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
AIM6 YDL237W Protein of unknown function physical 1 1 1 Affinity Capture-MS
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
ATG22 YCL038C Vacuolar integral membrane protein required for efflux of amino acids genetic 1 1 1 Negative Genetic
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly physical 1 1 1 Affinity Capture-MS